4-Aminobenzoic Acid (4 Aminobenzoic Acid)

A member of the VITAMIN B COMPLEX. It used to be common in SUNSCREENING AGENTS until found to also be a sensitizer. The potassium salt is used therapeutically in fibrotic skin disorders.

Also Known As:

Networked: 376 relevant articles (9 outcomes, 25 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Akberova, S I: 5 articles (09/2006 - 01/2000)
2.	Musaev Galbinur, P I: 4 articles (09/2006 - 01/2000)
3.	Hung, C F: 3 articles (10/2001 - 05/2000)
4.	Chung, J G: 3 articles (10/2001 - 05/2000)
5.	Mamedova, V M: 2 articles (09/2006 - 01/2001)
6.	Tazulakhova, E B: 2 articles (09/2006 - 01/2001)
7.	Yeh, C C: 2 articles (10/2001 - 03/2001)
8.	Stroeva, O G: 2 articles (07/2001 - 05/2000)
9.	Tinge, S A: 2 articles (06/2001 - 05/2001)
10.	Timoney, J F: 2 articles (06/2001 - 05/2001)

Related Diseases

1.	Exocrine Pancreatic Insufficiency 03/01/2000 - "Fifteen of these patients had pancreatic insufficiency (PI) established by urinary para-aminobenzoic acid test and fecal fat excretion. " 04/01/1997 - "The PABA/13C-PABA ratios in serum after 1.5 h were 2.64 +/- 0.14 (mean +/- SEM) in 10 healthy volunteers and 1.26 +/- 0.22 in 10 patients with exocrine pancreatic insufficiency. " 07/01/1992 - "A PABA excretion index (PEI) less than 55%, indicating moderate to severe exocrine pancreatic insufficiency (EPI), was found in 19% of the elderly group (95% confidence limits 5-42%). " 12/01/1990 - "In order to evaluate diagnostic sensitivity in relation to the degree of pancreatic insufficiency, results of NBT-PABA test were compared with the results of SPT. " 09/15/1988 - "The progressive decrease in plasma PABA levels indicated a potential for the late development of exocrine pancreatic insufficiency. "
2.	Malaria 12/01/2003 - "Our studies suggest that the PABA content in the diet will affect the host clearance of malaria parasites and may affect the efficacy of treatments that target the shikimate pathway." 12/01/2003 - "We show that, despite the presence of biosynthetic machinery to synthesize PABA, Plasmodium yoelii, a rodent malaria species, requires exogenous dietary PABA for survival. " 12/01/1966 - "[The importance of p-aminobenzoic acid to the course and immunity of malaria in animals (Plasmodium berghei) and in man (Pl. " 12/01/1966 - "[The importance of p-aminobenzoic acid to the course and immunity of malaria in animals (Plasmodium berghei) and in man (Pl. " 10/01/1966 - "[The importance of p-aminobenzoic acid to the course and immunity of malaria in animals (Plasmodium berghei) and in man (Pl. "
3.	Sunburn 09/01/1972 - "Tanning without sunburn with aminobenzoic acid-type sunscreen." 06/01/1950 - "[p-Aminobenzoic acid in the prevention of sunburn]." 12/01/1947 - "The sunburn-protecting effect of para-aminobenzoic acid." 01/01/1976 - "Pathak and Fitzpatrick showed that 5 % PABA in 70 % ethanol and 2,5 % Escalol 506 in 65 % ethanol is the most effective sunscreen against radiation of the sunburn spectrum. " 06/26/1969 - "Evaluation of topical agents that prevent sunburn--superiority of para-aminobenzoic acid and its ester in ethyl alcohol."
4.	Body Weight (Weight, Body) 09/15/1988 - "Weight loss was significantly greater in the irradiated dogs compared to the control (P less than 0.05) and the mean percentage of body weight loss correlated with the mean PABA values (P less than 0.01). " 12/01/1980 - "A solution of BT-PABA (1 g/100 ml) and d-xylose (10 g/100 ml) was given orally (5 ml/kg of body weight) to dogs in each group. " 05/01/1992 - "To study the pharmacokinetics of para-aminobenzoic acid (PABA), rats were subcutaneously injected with 3H-PABA (1 mkg/g body weight) at the stage (P7) when stimulation of outer segments of the photoreceptor cell morphogenesis is possible (Stroeva et al., 1990). " 12/01/1982 - "Plasma p-aminobenzoic acid (PABA) and xylose concentrations were determined before, and at 30, 60, 90, 120, 150, and 180 minutes after, a solution of bentiromide (1 g/100 ml) and D-xylose (10 g/100 ml) was given orally at a dosage of 5 ml/kg of body weight. "
5.	Erythema 12/01/1994 - "However, when mice were exposed to UVB radiation equivalent to 15 x MED, protection from erythema was observed only at the higher concentrations of each UVB absorber (10% 2-EHMC and 10% or 15% o-PABA). " 06/01/1987 - "Eight normal subjects, four of whom had been protected with the sunscreen para-aminobenzoic acid (sun protection factor 8), were exposed to one minimal erythema dose of UV radiation. " 11/01/1983 - "Topical application of IND 20 min prior to exposure to UVB in 2 human subjects resulted in an increase in the minimal erythema dose, giving a sun protection factor of 1.6, which is comparable to that produced by an equimolar concentration of para-aminobenzoic acid solution. " 02/01/1961 - "II. The effect of p-aminobenzoic acid and various derivatives on the development of ultraviolet erythema]." 10/01/1991 - "Topically applied 2-EHMC sunscreen protected totally from both forms of immunosuppression, but the o-PABA sunscreen failed to protect, although both sunscreens were equally effective in protection from UV radiation-induced erythema and edema."

Related Drugs and Biologics

1.	4-Aminobenzoic Acid (4 Aminobenzoic Acid)
2.	oxybenzone (Solbar)
3.	bentiromide
4.	Sunscreening Agents (Sunscreens)
5.	Vitamins
6.	Pancreatic Elastase (Elastase)
7.	Methoxsalen (Oxsoralen)
8.	octyl dimethyl 4-aminobenzoic acid
9.	sulisobenzone (Uval)
10.	Chymotrypsin

Related Therapies and Procedures

1.	Intravenous Injections
2.	Drug Therapy (Chemotherapy)
3.	Oral Administration
4.	Vocational Rehabilitation
5.	Total Parenteral Nutrition