P Blood-Group System

A blood group related to the ABO, Lewis and I systems. At least five different erythrocyte antigens are possible, some very rare, others almost universal. Multiple alleles are involved in this blood group.

Also Known As:

Blood-Group System, P; Blood-Group Systems, P; P Blood Group System; P Blood-Group Systems; System, P Blood-Group; Systems, P Blood-Group

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Biological Factors: 2472
- Antigens: 143924
  - Surface Antigens: 5813
    - Blood Group Antigens: 5213
      - P Blood-Group System: 6
  - Isoantigens: 1221
    - Blood Group Antigens: 5213
      - P Blood-Group System: 6

Experts

1.	Bovin, Nicolai V: 1 article (12/2011)
2.	Caduff, Rosemarie: 1 article (12/2011)
3.	Chinarev, Alexander: 1 article (12/2011)
4.	Fink, Daniel: 1 article (12/2011)
5.	Goldstein, Darlene R: 1 article (12/2011)
6.	Hacker, Neville: 1 article (12/2011)
7.	Heinzelmann-Schwarz, Viola: 1 article (12/2011)
8.	Huflejt, Margaret E: 1 article (12/2011)
9.	Jacob, Francis: 1 article (12/2011)
10.	Pochechueva, Tatiana: 1 article (12/2011)

Related Diseases

1.	Teratocarcinoma 12/01/1987 - "The predominant glycolipid antigens expressed by EC cells of both humans and mice have globoseries core structures; in humans they are terminally modified to yield the monoclonal antibody-defined stage-specific embryonic antigens SSEA-3 and SSEA-4, and also globo-ABH antigens; in the mouse terminal modification yields the Forssman antigen rather than SSEA-3 and -4. These observations focus attention on the possible role of the P-blood group system, which regulates synthesis of globoseries oligosaccharides, in the behavior of cells in the early embryo and in teratocarcinomas. "
2.	Zoonoses 01/01/1982 - "Abstract This paper suggests that the P2 allele of the P blood group system serves as an adaptation to a hypothesized Generalized Helminthic Antigenic Complex shared by many helminthic zoonoses. " 01/01/1982 - "Part 6: The P blood group system: Genetic adaptation to helminthic zoonoses."
3.	Pyelonephritis 01/01/1980 - "coli strains from children with acute febrile pyelonephritis failed to agglutinate human erythrocytes lacking the antigens within the P blood group system. "
4.	Ovarian Neoplasms (Ovarian Cancer) 12/01/2011 - "As another ligand we selected P(1), a member of the P blood group system recently identified by PGA as a potential ovarian cancer biomarker. "
5.	Rheumatoid Arthritis 11/01/1978 - "The illegitimate glycosphingolipid antigens of the P blood group system and of the Forssman (Fs) tissue antigen in adenocarcinoma which are foreign to the host suggest the self-nonself concept which applies also to numerous other diseases such as rheumatoid arthritis, lupus, gluomerulonephritis, and idiopathic acute hemolytic anemia. "

Related Drugs and Biologics

1.	Antigens
2.	Glycolipids
3.	Stage-Specific Embryonic Antigens
4.	Biomarkers (Surrogate Marker)
5.	Prostaglandins A
6.	Oligosaccharides
7.	Ligands
8.	Glycosphingolipids
9.	Forssman Antigen
10.	Monoclonal Antibodies