Cystinyl Aminopeptidase

01/01/2008 - "Notable among the neuropituitary disorders that can occur throughout pregnancy is diabetes insipidus, which occurs as a consequence of increased vasopressinase activity."
05/01/2005 - "Two cases of diabetes insipidus, believed to be due to excess vasopressinase, are presented to demonstrate the clinical features, pathogenesis, and treatment of this syndrome. "
03/01/1995 - "Posterior pituitary problems in pregnancy usually manifest by diabetes insipidus, with a pregnancy-specific variety resulting from excessive degradation of AVP by placental vasopressinase. "
06/01/1993 - "Serum vasopressinase activity was measured during one of the pregnancies affected with diabetes insipidus and compared with that obtained between 26 and 38 weeks from 13 normal pregnancies. "
02/01/1991 - "These increases (MCR of AVP and plasma vasopressinase) may explain certain syndromes of transient diabetes insipidus (DI) that complicate gestation. "

08/01/2005 - "Oxytocinase serum level during pregnancy rises with the fetal development and arrest of oxytocinase serum growth might indicate the its development impairment, what might result in spontaneous abortion. "
04/01/2001 - "Serum oxytocinase and isosoxytocinase levels were evaluated in 157 women who delivered and in 77 women who had spontaneous miscarriage. "
04/01/2001 - "The aim of our study was to compare serum levels of oxytocinase (CAP1) and isooxytocinase (CAP2) in the first trimester of pregnancy between women who had miscarriage and those who delivered healthy babies. "
08/01/2005 - "Changes of maternal ACTH and oxytocinase plasma concentrations during the first trimester of spontaneous abortion."

12/15/1980 - "The aim of this study was to correlate the relationship between serum cystine aminopeptidase (CAP) activity in normal patients and that in patients with primary ovarian cancer of recurrence. "
12/15/1980 - "Early primary diagnosis of ovarian cancer and detection of recurrence by serum cystine aminopeptidase assay."

03/01/2014 - "This study highlights the importance of the oxytocin system in the pathogenesis of obesity and suggests oxytocinase inhibition as a candidate approach in the therapy of obesity. "

01/01/1995 - "This association between excessive vasopressinase production and pre-eclampsia might be explained if the products of AVP degradation by vasopressinase retained pressor activity even after anti-diuretic activity had been destroyed. "
01/01/1993 - "Oxytocinase (EC 3.4.11.3) activity was determined in 80 amniotic fluid samples obtained from 40 normotensive primigravidas (median age 27 years) and 40 primigravidas (median age 29 years) with pregnancies complicated by preeclampsia between 32 and 39 weeks of gestation. "
01/01/1993 - "Decreased levels of amniotic fluid oxytocinase activity in preeclampsia."
09/01/1983 - "However, elevated maternal ADH secondary to fetal hypothalamic ADH production and a genetic defect in maternal vasopressinase may be a cause of preeclampsia."
11/01/1964 - "PREECLAMPSIA ASSOCIATED WITH DECREASE IN SERUM OXYTOCINASE."