Oxyhemoglobins (Oxyhemoglobin)

A compound formed by the combination of hemoglobin and oxygen. It is a complex in which the oxygen is bound directly to the iron without causing a change from the ferrous to the ferric state.

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Networked: 720 relevant articles (25 outcomes, 65 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Gottlieb, Daniel J: 6 articles (01/2015 - 10/2006)
2.	Gozal, David: 5 articles (06/2013 - 03/2006)
3.	Querido, Jordan S: 5 articles (09/2012 - 03/2008)
4.	Tromberg, Bruce J: 5 articles (09/2012 - 06/2003)
5.	Dimsdale, Joel E: 5 articles (12/2008 - 04/2006)
6.	Sanders, Mark H: 5 articles (07/2008 - 02/2003)
7.	Tufik, Sergio: 4 articles (06/2015 - 10/2012)
8.	Redline, Susan: 4 articles (01/2015 - 05/2002)
9.	Katayama, Yoichi: 4 articles (01/2014 - 06/2006)
10.	Sakatani, Kaoru: 4 articles (01/2014 - 06/2006)

Related Diseases

1.	Apnea 04/01/1987 - "The comparison of a nocturnal polygraphic study performed during spontaneous breathing with a study during CPAP administration performed the following night showed a significant reduction in stage 1 and increase in REM, the abolition of obstructive apneas and a significant increase in mean oxyhemoglobin saturation. " 10/01/2001 - "Specifically, stimulation significantly reduced the mean apnea-hypopnea indices in non-rapid eye movement (mean +/- SD episodes per hour, 52.0 +/- 20.4 for baseline nights and 22.6 +/- 12.1 for stimulation nights; P<.001) and rapid eye movement (48.2 +/- 30.5 and 16.6 +/- 17.1, respectively; P<.001) sleep and reduced the severity of oxyhemoglobin desaturations. " 01/01/1984 - "Nasal CPAP of 5-10 cm H2O decreased apnea index (apneas per hour of sleep) (control 35.1, n-CPAP 5.7; p less than 0.001) and significantly improved oxyhemoglobin saturation (SaO2). " 04/01/2006 - "CPAP improved, to within normal limits, the apnea-hypopnea index, total arousal index, and mean oxyhemoglobin saturation (p < or = .001). " 06/01/2005 - "An improvement in both apnea-hypopnea index and minimum arterial oxyhemoglobin saturation occurred consistently in all subjects postnatally. "
2.	Anoxia (Hypoxia) 12/01/1989 - "Improved nocturnal hypoxemia: mean minimum oxyhemoglobin saturation (SAO2) before and after UPPP in NREM sleep 83 +/- 4% v. 90 +/- 4% in REM sleep 76 +/- 11% v. 85 +/- 7%. " 09/15/2014 - "The purpose of this study was to test the hypothesis that oxyhemoglobin equilibrium and tachycardiac responses during hypoxemia were enhanced after 14-day IH exposures. " 01/01/2013 - "The study was closed early due to significantly severe hypoxemia events (oxyhemoglobin saturation <70%) in the group titrated at 0.5 μg/ml. Forty-nine, 49 and 46 patients were enrolled into the 3 respective groups before study closure. " 01/01/2015 - "Significant OSA was defined as respiratory disturbance index ≥ 15, and nocturnal hypoxemia was defined as oxyhemoglobin saturation < 90% for ≥ 12% of total monitoring time. " 09/15/2014 - "Two-week normobaric intermittent hypoxia exposures enhance oxyhemoglobin equilibrium and cardiac responses during hypoxemia."
3.	Central Sleep Apnea (Central Sleep Apnea Syndrome) 12/15/1999 - "Treatment with O2 resulted in a significant reduction in AHI (49+/-19 vs 29+/-29, means+/-SD), central apnea index (28+/-23 vs 13+/-18 per hour), and the percent of total sleep time below an arterial oxyhemoglobin saturation of 90% (23+/-21% vs 0.8+/-2.3%). " 07/01/2003 - "SHHS methodologies have been previously reported and include performance of overnight, in-home polysomnography (PSG), which recorded variables reflecting sleep architecture and breathing, permitting identification of obstructive and central apneas, hypopneas, periodic breathing and oxyhemoglobin saturation (SpO(2)). " 05/01/2002 - "Relative to the first-night PSG, on the second PSG, we observed the following: shorter latency to rapid eye movement (REM) sleep (P<0.001), increased sleep efficiency (P<0.01), decreased wake after sleep onset (WASO) time (P<0.01), decreased percentage of non-REM time with oxyhemoglobin saturation by pulse oximetry (SpO(2))< or =90% (P<0.05), decreased number of central apneas per hour (P<0.05) and reduced respiratory rate in stage 2 sleep on night 2 (P<0.05). " 09/01/2012 - "In the ASV group, indices for apnea-hypopnea, central apnea, and oxyhemoglobin saturation were improved on ASV. " 03/01/2006 - "Snoring-associated arousals accounted exclusively for this relationship; spontaneous arousals and those that were associated with central apnea and oxyhemoglobin desaturation episodes (> or =4%) were not significantly correlated with MDI. "
4.	Chronic Obstructive Pulmonary Disease (COPD) 01/01/2001 - "According to our study we can conclude that (1) ET-1 levels are significantly higher in 'desaturator' COPD patients both during the day and during the night, and (2) ET-1 levels correlate negatively significant with the degree of the oxyhemoglobin desaturation. " 01/01/2001 - "The aim of this study was to examine a possible correlation between ET-1 levels and nocturnal, nonapneic, oxyhemoglobin desaturation during sleep, in patients with COPD. " 08/01/1991 - "We studied 31 clinically stable chronic obstructive pulmonary disease (COPD) patients with a PaO2 greater than or equal to 60 mm Hg using polysomnographic sleep study at baseline (between 1983 and 1986) and at a mean follow-up time of 42.5 months to examine the evolution of rapid-eye-movement (REM) sleep nocturnal oxyhemoglobin desaturation (NOD). " 01/01/1988 - "A polysomnographic study with noninvasive oxyhemoglobin saturation (HbSaO2) monitoring has been conducted in 11 consecutive male nonobese subjects with chronic obstructive pulmonary disease (COPD). " 03/01/2014 - "Kinetics of changes in oxyhemoglobin saturation during walking and cycling tests in COPD."
5.	Obstructive Sleep Apnea 06/20/2013 - "We hypothesized that, in children with the obstructive sleep apnea syndrome without prolonged oxyhemoglobin desaturation, early adenotonsillectomy, as compared with watchful waiting with supportive care, would result in improved outcomes. " 01/01/2009 - "To comprehensively evaluate the ability and reliability of the representative previously proposed oxyhemoglobin indexes derived automatically for predicting the severity of obstructive sleep apnea hypopnea syndrome (OSAHS). " 01/01/2009 - "Comparison of the indices of oxyhemoglobin saturation by pulse oximetry in obstructive sleep apnea hypopnea syndrome." 05/01/2005 - "Obstructive sleep apnea and hypopnea syndrome (OSAHS) are characterized by repeated pauses in breathing during sleep, usually associated with sleep interruption and decreased oxyhemoglobin saturation. " 06/01/2003 - "Obstructive sleep apnea (OSA) refers to the occurrence of episodes of complete or partial pharyngeal obstruction with oxyhemoglobin desaturation during sleep. "

Related Drugs and Biologics

1.	Oxygen
2.	Hemoglobins (Hemoglobin)
3.	deoxyhemoglobin
4.	Carbon Dioxide
5.	Nitric Oxide (Nitrogen Monoxide)
6.	Electron Transport Complex IV (Cytochrome c Oxidase)
7.	Acetazolamide (Diamox)
8.	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)
9.	Methylprednisolone
10.	Doxapram (Doxapram Hydrochloride)

Related Therapies and Procedures

1.	Warm Ischemia
2.	Aftercare (After-Treatment)
3.	Lasers (Laser)
4.	Hormone Replacement Therapy (Therapy, Hormone Replacement)
5.	Mandibular Advancement