Oxides

06/21/1996 - "The OMe-substituted N-oxides all showed greater metabolic stability than 2 in hypoxic AA8 cell cultures, and the 4-OMe compound 6 had improved activity in EMT6 multicellular spheroids suggesting that this metabolic stabilization may allow more efficient diffusion in tumor tissue. "
03/01/2015 - "The aim of this study was to investigate the reaction of normal and tumor cells to genotoxic effect of widespread environmental factors - exogenous nitric oxides and ionizing radiation. "
01/15/2004 - "This study demonstrates that benzotriazine mono-N-oxides have potential use for improving the therapeutic utility of TPZ as a hypoxic cytotoxin in cancer treatment."
03/01/2016 - "The metals and metal oxides were investigated with respect to their antimicrobial and anticancer effects towards bacteria and cancer cell line. "
07/28/2015 - "Metal oxides are receiving an incremental attention in recent years for their potential applications in ablation of cancer cells due to their efficient photothermal conversion and good biocompatibility, but the large sizes and poor photo-stability will seriously limit their practical application. "

03/01/2011 - "There is now increasing recognition that some staple and widely consumed foods are sometimes contaminated by dehydroPAs and their N-oxides at levels that, while insufficient to cause acute poisoning, greatly exceed maximum tolerable daily intakes and/or maximum levels determined by a number of independent risk assessment authorities. "
06/28/2010 - "With growing interest in the oxidation activity of metal oxides, it is important to understand and ultimately to learn to bypass surface poisoning. "
01/01/1991 - "4. The resistance of guinea-pigs to PA poisoning is attributed to the high metabolism of PAs to N-oxides combined with a corresponding low conversion to pyrrolic metabolites."
07/28/1893 - "THREE SHIPS WITH BERIBERI OUTBREAKS SHOWN TO HAVE HAD EXTENSIVE FORMATION OF CARBONIC OXIDES DURING THE VOYAGE -- ANALYSIS OF BERIBERI BLOOD --CONCLUSION THAT BERIBERI IS NOTHING BUT CARBONIC POISONING OF THE BLOOD."
12/01/2014 - "Product analysis and surface chemistry investigations using high-resolution X-ray photoelectron spectroscopy (HR-XPS) reveal that NO3(-) decreased particle reactivity mainly due to progressive formation of passivating oxides, whereas SO4(2-) and phosphate elicited rapid deactivation as a result of specific poisoning of the surface nickel sites. "

07/01/2002 - "[The effect of dose distribution on risk of lung cancer after inhalation of actinide oxides]."
03/01/2012 - "This resulted in the predominant occurrence of skeletal cancers in animals exposed to 238Pu oxides but lung cancers in those with exposures to 239Pu oxides. "
03/01/2009 - "This study did not detect any relationship between exposure to iron oxides and lung cancer mortality. "
03/01/2009 - "Among males, observed mortality was lower than expected for lung cancer compared to the local population (233 deaths, SMR 0.89, 95% CI 0.78 to 1.01) and higher than expected compared to the French population (SMR 1.30, 95% CI 1.15 to 1.48) No lung cancer excess was observed for exposure to iron oxides (RR 0.80, 95% CI 0.55 to 1.17) and no dose-response relationship with intensity, duration of exposure or cumulative index was found. "
01/01/2009 - "A weak but consistent lung cancer excess in many populations exposed to iron oxides but it is not possible to state on causality. "

07/01/2014 - "In addition to cholesterol, PS can also be oxidized during food processing or storage, and the oxidized derivatives, known as phytosterol oxidation products (POPs), can make an important contribution to the negative effects of both cholesterol and cholesterol oxidation oxides (COPs) in relation to inflammatory disease onset and the development of atherosclerosis. "
01/01/2014 - "However other N-oxides, such as furoxans with anti-inflammatory and anti-atherosclerosis activities, seem to lack mutagenicity. "
08/01/2009 - "Higher plasma concentrations of the endogenous nitric oxides synthase inhibitor asymmetrical dimethylarginine (ADMA) are associated with increased risk of cardiovascular and cerebrovascular events and death, presumably by promoting endothelial dysfunction and subclinical atherosclerosis. "
02/01/2000 - "Cholesterol feeding after balloon injury in a rabbit model of atherosclerosis is known to result in the accumulation of cholesterol oxides. "
02/01/2000 - "The ability of cholesterol and its oxides to induce apoptosis in vascular smooth muscle cells in tissue culture and in a rabbit model of atherosclerosis was evaluated. "

03/15/2013 - "N-Oxides have the tendency to form abundant 'non-classical' dimers under ESI, which fragment via dehydration rather than giving their corresponding monomer. "
03/28/2012 - "Besides, special interest was given to In-Zn mixed oxides for their enhanced basicity: this series of catalysts displays important basic features of high strength (q(diff) (SO₂ ads.) > 200 kJ mol(SO₂)⁻¹ in substantial amounts (1 - 2 μmol m(catalyst)⁻²), whose impact on efficiency or selectivity in catalytic dehydration/dehydrogenation can be valuable."
07/23/1975 - "Letter: Novel rearraNgements during dehydration of nucleophile adducts of arene oxides. "
03/01/2001 - "The mechanical stability of the oxides was evaluated by ultrasonication in distilled water followed by dehydration and rehydration. "
07/05/2010 - "Partial dehydration of the two precursors leads to new phases [Dy(2)(H(2)O)(6)](Mo(8)O(27)) and [Nd(2)(H(2)O)(6)]Mo(8)O(27) x 3 H(2)O, respectively, prior to complete dehydration, which leads to initially amorphous and eventually crystalline rare-earth molybdenum mixed metal oxides. "