Osteoma

A benign tumor composed of bone tissue or a hard tumor of bonelike structure developing on a bone (homoplastic osteoma) or on other structures (heteroplastic osteoma). (From Dorland, 27th ed)

Also Known As:

Networked: 282 relevant articles (11 outcomes, 9 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Choroidal Neovascularization
2.	Hemorrhage
3.	Cicatrix (Scar)
4.	Wounds and Injuries (Trauma)
5.	Headache (Headaches)

Experts

1.	Shields, Carol L: 6 articles (03/2015 - 12/2007)
2.	Shields, Jerry A: 6 articles (03/2015 - 12/2007)
3.	Ceran, Basak Bostanci: 2 articles (05/2015 - 09/2014)
4.	Coban, Deniz Turgut: 2 articles (05/2015 - 09/2014)
5.	Hasanreisoglu, Murat: 2 articles (03/2015 - 01/2015)
6.	Tuncer, Samuray: 2 articles (07/2014 - 01/2014)
7.	Ramakrishnan, Vijay R: 2 articles (03/2014 - 05/2013)
8.	Lai, Timothy Y Y: 2 articles (01/2014 - 05/2012)
9.	Sisk, Robert A: 2 articles (01/2014 - 01/2013)
10.	Ahmadieh, Hamid: 2 articles (01/2014 - 11/2007)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Osteoma:

1.	bevacizumabFDA Link 03/01/2014 - "Intravitreal bevacizumab can be used to successfully treat subretinal fluid associated with choroidal osteomas and may lead to an improvement in BCVA." 05/01/2008 - "To describe a patient with choroidal neovascular membrane (CNVM) secondary to choroidal osteoma treated successfully with intravitreal bevacizumab. " 07/01/2014 - "CNV secondary to choroidal osteoma was treated with intravitreal bevacizumab and it responded well. " 07/01/2014 - "Bilateral choroidal osteoma with choroidal neovascular membrane treated with bevacizumab in a child." 04/01/2011 - "Intravitreal Bevacizumab may be an effective alternative in the management of CNVM secondary to choroidal osteoma. "
2.	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/01/2014 - "We conclude that intravitreal anti-VEGF injections improve vision in majority of eyes with CNV from choroidal osteoma. " 03/01/2014 - "The authors report the use of an anti-VEGF agent in the resolution of subretinal fluid and hemorrhage with improvement in best corrected visual acuity (BCVA) in a patient with choroidal osteoma. " 09/01/2014 - "Outcomes of anti-vascular endothelial growth factor therapy in the management of choroidal neovascularization associated with choroidal osteoma." 03/01/2014 - "Successful use of anti-VEGF treatment for subretinal hemorrhage and fluid in a young patient with choroidal osteoma." 01/01/2008 - "Therapy with intravitreal anti-VEGF medications might be an alternative for patients with choroidal neovascularization overlying choroidal osteoma."
3.	CosmeticsIBA 04/01/2014 - "Treatment is indicated for symptomatic osteomas or cosmetic reasons." 03/01/2013 - "Ten of the 149 patients underwent surgery for cosmetic and/or rapidly growing osteomas. " 04/01/2012 - "UBA was used to successfully remove a forehead osteoma without injury to adjacent nerves and with a satisfactory cosmetic outcome. " 03/01/2012 - "The purpose of this article was to present the successful surgical removal of ethmoid osteoma through lamina papyracea and transcaruncular approach, resulting in both successful surgical correction and good cosmetic outcome." 07/01/2011 - "Diagnosis of frontal osteoma is usually by chance, but rarely these can produce exceptional ophthalmologic and neurological complications apart from cosmetic disfigurement. "
4.	Retinaldehyde (Retinal)IBA 12/01/1995 - "Additional studies revealed that he also had minor dental abnormalities, a small osteoma on the right mandible, and unilateral, ocular, pigmented retinal macules. " 01/01/2015 - "Spectral domain optical coherence tomography of the left macula showed preserved retinal layers and RPE with underlying calcified choroidal osteoma. " 04/01/2010 - "Macular choroidal osteoma with progressive widespread outer-retinal dysfunction." 12/01/2007 - "Retinal status over the calcified and decalcified portions of choroidal osteoma. " 12/01/2007 - "To evaluate the retinal status overlying choroidal osteoma using optical coherence tomography (OCT). "
5.	Cyclosporine (Ciclosporin)FDA LinkGeneric 11/01/1985 - "During the course of a long-term oral study in OF-1 mice for the assessment of any carcinogenic potential of the immunosuppressive agent cyclosporine (CS-A), a high incidence of osteomas was found in all treatment groups as well as in controls. " 11/01/1985 - "Osteomas in OF-1 mice: no alteration in biologic behavior during long-term treatment with cyclosporine."
6.	DNA (Deoxyribonucleic Acid)IBA 01/01/2011 - "The aim of this study was to find differences in gene expression patterns in canine mammary osteosarcomas (malignant) versus osteomas (benign) using DNA microarrays. "
7.	Fumigant 93 (D-D)IBA 03/01/2014 - "The medical records of patients with primary (originating from orbital bone) and secondary (originating from the paranasal sinuses) orbital osteoma from the academic practices of 4 surgeons (A.V.C., M.J.L., P.J.D., V.D.D.) were reviewed for clinical presentation and course, pathologic study, and radiologic reports. "
8.	Albright's hereditary osteodystrophyIBA 08/01/2013 - "Osteoma cutis in a patient with Albright hereditary osteodystrophy (AHO)." 03/01/2010 - "POH is at the severe end of a spectrum of GNAS-associated ossification disorders that include osteoma cutis and Albright Hereditary Osteodystrophy (AHO). " 10/01/2008 - "Albright hereditary osteodystrophy is a rare syndrome, in which cutaneous and superficial soft tissue lesions traditionally include osteomas and calcifications. " 01/01/1994 - "[Cutaneous osteoma and Albright's hereditary osteodystrophy]." 03/01/1992 - "Osteoma cutis is a common sign of Albright hereditary osteodystrophy in infancy and childhood, and its significance should not be overlooked, even in the normocalcemic patient."
9.	Fluorescein (Funduscein)FDA LinkGeneric 05/01/2014 - "Upon a complete ophthalmologic examination, including fundus fluorescein angiography and optical coherence tomography, he was diagnosed with choroidal osteoma-related subfoveal CNV in the left eye. " 10/01/1994 - "During follow-up observation, fluorescein angiography confirmed the extension of the osteoma into this area. " 10/01/1992 - "All three osteomas were demonstrated by ocular ultrasound (US), fluorescein angiography (FA) and computed tomography (CT) but none by plain radiography. " 11/01/1984 - "Two patients with choroidal osteoma, one with bilateral involvement, diagnosed by fluorescein angiography, ultrasonography and CT scanning are presented. " 01/01/2014 - "The article presents a case of a 26-year-old woman with bilateral choroidal osteoma complicated by subretinal hemorrhage; the diagnosis was based on clinical examination (biomicroscopy and indirect ophthalmoscopy) as well as specialised tests including: ultrasonography, optical coherence tomography, and fluorescein angiography."
10.	ranibizumab (Lucentis)FDA Link 09/01/2014 - "We report the case of a 28-year-old female with CNV secondary to choroidal osteoma, who developed RPE tear after intravitreal ranibizumab treatment." 05/01/2012 - "Our findings suggest that intravitreal ranibizumab may be an effective therapeutic option for treating CNV secondary to choroidal osteoma." 05/01/2012 - "We present a case of CNV secondary to choroidal osteoma treated with intravitreal ranibizumab. " 01/01/2012 - "Paediatric choroidal osteoma treated with ranibizumab." 05/01/2014 - "This report shows the favorable outcome of intravitreal injection of ranibizumab in choroidal osteoma-related CNV in a child. "

Therapies and Procedures

1.	Craniotomy 09/01/2008 - "The main surgical procedure was resection of the osteoma using orbitotomy and/or craniotomy followed by orbital reconstruction and cranioplasty. " 08/01/2004 - "Through a right frontal craniotomy, the air cavity was evacuated, the osteoma partially excised, and the dural defect closed using a vascularized pericranial flap. " 12/01/1998 - "Through a wide bilateral frontal craniotomy, the cauliflower-like osteoma was found to be protruding intracranially through the skull base and the overlying dura mater. " 10/01/1992 - "The four panorbital osteomas required large frontotemporal craniotomies in association with superolateral orbitotomy and zygomatic and/or malar osteotomy, when necessary. " 12/01/2009 - "The osteoma was resected by combining endoscopic sinus surgery with bifrontal craniotomy and the patient was relieved of headaches."
2.	Surgical Equipment 01/01/2013 - "While the extranasal approach is still a part of the treatment concept for removing osteomas; over the last years, in suitable cases, the endoscopically controlled endonasal approach has greatly gained importance due to the improved surgical equipment and experience." 04/01/2011 - "While the extranasal approach is still a part of the treatment concept for removing osteomas at this localization, over the last years the endoscopically controlled endonasal approach has greatly gained in importance due to the improved surgical equipment. "
3.	Endoscopes 05/01/2006 - "The authors have found that excision of forehead osteoma using an endoscope coupled with proper instruments to be very safe and effective with minimal morbidity." 05/01/2006 - "The purpose of this study is to present our clinical experience with 12 consecutive forehead osteomas that were excised with the aid of an endoscope. " 01/01/2013 - "During surgery, the complete surgical field was within the view of the endoscope, thereby enabling the surgeon to easily resection the osteoma with the piezosurgery device. " 11/01/2012 - "Two-hole trephination was planned to remove the osteoma using nasal endoscope and a drill in each hole. " 02/01/2011 - "The ethmoid osteoma in all 19 patients was removed successfully with endoscope and navigation system. "
4.	Sutures (Suture) 01/01/2001 - "The technique of scalpel incision over visible lesions, curette extraction of bony fragments, and primary suture repair was used to remove multiple lesions of primary miliary osteoma cutis on the cheeks of an affected patient. " 02/01/1991 - "In a retrospective analysis of 12 osteomas, we found that the localisation influences the histological architecture: In osteomas of suture origin, the fibrovascular component is significantly reduced. " 02/01/1991 - "The sites of osteomas of the frontal and temporal bone are mostly the sutures and only rarely the flat bones. " 05/01/1982 - "The solitary osteoma is an uncommon unilateral lesion, attached to the tympanosquamous or tympanomastoid suture line, almost always in the outer half of the ear canal. " 04/01/1982 - "Osteomas are usually solitary, pedunculated, bony growths attached to the tympanosquamous or tympanomastoid suture line, characterized histologically by an internal structure of abundant discrete fibrovascular channels surrounded by irregularly oriented lamellated bone. "
5.	Injections 08/01/1986 - "Newborn female strain NMRI mice were given injections of a mouse retrovirus (OA MuLV) known to induce osteopetrosis, osteoma, and lymphoma. " 01/01/2014 - "We conclude that intravitreal anti-VEGF injections improve vision in majority of eyes with CNV from choroidal osteoma. " 09/01/2014 - "To investigate the efficacy of serial anti-vascular endothelial growth factor injections for choroidal neovascularization associated with choroidal osteoma. " 05/01/2015 - "Nine eyes (75%) developed RPE tears during ranibizumab injections for choroidal neovascularization (eight eyes with vascularized PED and one eye with choroidal osteoma), and tears occurred in three eyes before any injections. " 01/01/2014 - "Role of Intravitreal Antivascular Endothelial Growth Factor Injections for Choroidal Neovascularization due to Choroidal Osteoma."