Osmium Tetroxide

(T-4)-Osmium oxide (OsO4). A highly toxic and volatile oxide of osmium used in industry as an oxidizing agent. It is also used as a histological fixative and stain and as a synovectomy agent in arthritic joints. Its vapor can cause eye, skin, and lung damage.

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Networked: 140 relevant articles (4 outcomes, 12 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Gorgani-Firouzjaee, T: 1 article (10/2015)
2.	Naem, S: 1 article (10/2015)
3.	Farshid, A A: 1 article (10/2015)
4.	Schneider, Jan Philipp: 1 article (02/2014)
5.	Ochs, Matthias: 1 article (02/2014)
6.	Stouffer, Mark H: 1 article (01/2013)
7.	Gayton, J Christopher: 1 article (01/2013)
8.	Rubino, L Joseph: 1 article (01/2013)
9.	Rich, Mark M: 1 article (01/2013)
10.	Wang, Qingbo: 1 article (01/2013)

Related Diseases

1.	Synovitis 07/01/1976 - "When an immune synovitis was induced in both knees of 16 rabbits, the osmic acid treated joint demonstrated a significantly greater synovitis and progressive aberrations compared to the untreated knee." 06/01/1975 - "On the basis of previous investigations and this study osmic acid is one alternative to radiation or surgical synovectomy in rheumatoid synovitis. " 09/01/2003 - "Chemical synovectomy with osmic acid has been used for many years in the treatment of chronic synovitis that is unresponsive to systemic treatment and intra-articular corticosteroid. " 01/01/1981 - "Osmic acid versus yttrium-90 in rheumatoid synovitis of the knee." 01/01/1980 - "chemical synovectomy with osmic acid was performed in 3 children because of persistent synovitis in the knee joint. "
2.	Hemophilia A (Haemophilia) 07/01/2001 - "Chemical synoviorthesis with osmic acid in haemophilia." 04/01/1998 - "The clinical efficacy of synovectomy done, using radiocolloids or osmic acid in arthropathy due to von Willebrand's disease, seems similar to that in hemophilia." 07/01/2001 - "Based on previous experience in inflammatory arthritis, a small number of open studies have evaluated the usefulness of chemical synoviorthesis with osmic acid in haemophilia, with various assessment criteria and a wide range of follow-up periods. "
3.	Knee Osteoarthritis 02/01/1996 - "The objective of this retrospective study was to compare the efficacy of osmic acid or radiation synovectomy with that of joint lavage for the treatment of knee osteoarthritis with effusions. "
4.	von Willebrand Diseases (von Willebrand's Disease) 04/01/1998 - "The clinical efficacy of synovectomy done, using radiocolloids or osmic acid in arthropathy due to von Willebrand's disease, seems similar to that in hemophilia."
5.	Malaria 10/01/1986 - "With the osmium tetroxide-zinc iodide impregnation technique the visualization of the internal organization of the exoerythrocytic form of the rodent malaria parasite Plasmodium berghei was improved. "

Related Drugs and Biologics

1.	zinc iodide
2.	Glutaral (Glutaraldehyde)
3.	Yttrium
4.	uranyl acetate
5.	Formaldehyde (Formol)
6.	Ruthenium Red
7.	Polyvinyl Chloride (PVC)
8.	hydroxyethyl methacrylate (HEMA)
9.	Ethanol (Ethyl Alcohol)
10.	Acetone

Related Therapies and Procedures

1.	Intra-Articular Injections
2.	Injections
3.	Aftercare (After-Treatment)
4.	Lenses
5.	Prostatectomy (Retropubic Prostatectomy)