Organotin Compounds

02/01/1998 - "Electrostatic inhibition of hemolysis induced by organotin compounds."
02/01/1998 - "The studies performed indicate that hemolysis induced by organotin compounds is inhibited due to electrostatic interaction between the cations selected and erythrocyte membrane."
02/01/1998 - "The ions used in the investigation diminish or totally inhibit hemolysis of red cells induced by organotin compounds. "
02/01/1998 - "The effect of cations on the kinetics of hemolysis caused by organotin compounds was studied. "
02/01/1998 - "The study has also shown the monovalent ions K+ and trimethyldodecylammonium bromide are less potent inhibitors of hemolysis than divalent ions, which is not the case for two non-ionic organotin compounds only. "

10/30/2023 - "In this study, organotin compounds known as triphenyltin ethyl phenyl dithiocarbamate and triphenyltin butyl phenyl dithiocarbamate were investigated for their toxicity on leukemia cell line (K562) and non-cancerous cell line (Chang liver cell and lung fibroblast, V79 cell). "

01/01/1991 - "When taken together with our previous study demonstrating spindle inhibiting effects of the same organotin compounds by an indirect method (Jensen et al., 1989), the present study strongly indicates that organotin compounds are able to induce aneuploidy, probably by affecting spindle function."
01/01/1991 - "Organotin compounds induce aneuploidy in human peripheral lymphocytes in vitro."

09/01/2009 - "It follows that these increases in cell death induced by these organotin compounds likely contributed to the thymic atrophy observed in the rats here."
09/01/2009 - "Organotin compounds are known to cause thymic atrophy and an accompanying deficiency of cell-mediated immunity. "
08/01/2009 - "Reduction in peripheral lymphocytes and thymus atrophy induced by organotin compounds in vivo."
12/01/1997 - "Thus, although apoptosis is involved in the in vitro cytotoxic effects of both organotin compounds, it seems not involved in thymus atrophy at a dose that selectively inhibits immature thymocyte proliferation."
07/01/1994 - "In the mid-seventies it appeared that some organotin compounds selectively caused thymus atrophy. "

06/01/2011 - "Cytotoxic effects of two organotin compounds and their mode of inflicting cell death on four mammalian cancer cells."
01/01/1994 - "The organotin compounds inhibit tumor cells by its [SnR2]2+, and inhibit G1-->S phases of HL-60 cell cycle. "
10/30/2020 - "Organotin compounds represent potential cancer therapeutics due to their pro-apoptotic action. "
09/01/2022 - "The cytotoxicity of both the organotin(IV) compounds and the tin-functionalized SBA-15 materials are studied against different cancer cell lines observing that the materials have similar cytotoxic activity in comparison with the free organotin compounds in terms of mass. "