Oral Submucous Fibrosis

Also Known As:
Fibroses, Oral Submucous; Fibrosis, Oral Submucous; Oral Submucous Fibroses; Submucous Fibroses, Oral; Submucous Fibrosis, Oral
Networked: 283 relevant articles (17 outcomes, 78 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Oral Leukoplakia
2. Mouth Neoplasms (Oral Cancer)
3. Oral Lichen Planus
4. Neoplasms (Cancer)
5. Precancerous Conditions


1. Chang, Yu-Chao: 10 articles (09/2014 - 02/2002)
2. Chen, Hsin-Ming: 8 articles (09/2015 - 07/2003)
3. Tsai, Chung-Hung: 8 articles (09/2013 - 07/2002)
4. Chiang, C P: 7 articles (08/2002 - 03/2000)
5. Yang, Shun-Fa: 6 articles (09/2014 - 02/2002)
6. Chou, Ming-Yung: 6 articles (10/2005 - 02/2002)
7. Chiang, Chun-Pin: 6 articles (04/2004 - 04/2002)
8. Li, Ning: 5 articles (06/2015 - 09/2008)
9. Kuo, Mark Yen-Ping: 5 articles (03/2013 - 07/2003)
10. Mehrotra, Ravi: 5 articles (11/2011 - 01/2010)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Oral Submucous Fibrosis:
1. lycopeneIBA
2. Hyaluronoglucosaminidase (Hyaluronidase)FDA Link
3. Triamcinolone Acetonide (Azmacort)FDA LinkGeneric
4. SteroidsIBA
01/01/2011 - "A rare ocular complication following treatment of oral submucous fibrosis with steroids."
10/01/2010 - "Efficacy of alpha lipoic acid in adjunct with intralesional steroids and hyaluronidase in the management of oral submucous fibrosis."
08/01/1991 - "Three hundred twenty-six patients with oral submucous fibrosis were divided into two groups and treated either with conventional submucosal injections of steroids and hyaluronidase, or with topical vitamin A, steroid applications, and oral iron preparations. "
01/01/2010 - "The drugs used to treat oral submucous fibrosis (OSF) were categorised into steroids, enzymes, cardiovascular drugs, antioxidants, vitamins and microelements. "
10/01/2010 - "Reliable evidence for management of oral submucous fibrosis is still limited; amifostine, hydrolytic enzymes, ice chips and Chinese medicine may be effective in preventing oral mucositis for patients with cancer receiving radiotherapy or chemotherapy; the evidence in treating oral mucositis with allopurinol mouthwash, granulocyte macrophage-colony stimulating factor, immunoglobulin or human placentral extract for patients with cancer receiving treatment is weak and unreliable yet; there is evidence that acyclovir is efficacious in prevention and treatment of herpes simplex virus infections in patients being treated for cancer; there is strong evidence that drugs absorbed or partially absorbed from the gastrointestinal tract prevent oral candidiasis in patients receiving treatment for cancer; relapses and adverse effects are common in using beta carotene, lycopene, vitamin A or retinoids to treat oral leukoplakia; only some weak evidence is provided in using cyclosporines, retinoids, steroids or phototherapy for treating oral lichen planus; the evidence about acyclovir for treating primary herpetic gingivostomatitis is insufficient; there is little research evidence for treatment of burning mouth syndrome. "
5. CopperIBA
6. CollagenIBA
7. IronIBA
8. ZincIBA
9. Dexamethasone (Maxidex)FDA LinkGeneric
10. salvianolic acid BIBA

Therapies and Procedures

1. Injections
2. Free Tissue Flaps
3. Solid-State Lasers
4. Drug Therapy (Chemotherapy)
5. Radiotherapy