Ophthalmic Solutions (Eye Drops)

Sterile solutions, essentially free from foreign particles and suitably compounded and dispensed, for instillation into the eye. It does not include solutions for cleaning eyeglasses or CONTACT LENS SOLUTIONS. (From Dorland, 27th ed)

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Networked: 2232 relevant articles (256 outcomes, 308 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Babizhayev, Mark A: 17 articles (12/2015 - 01/2004)
2.	Ito, Yoshimasa: 17 articles (03/2015 - 07/2004)
3.	Nagai, Noriaki: 15 articles (03/2015 - 08/2007)
4.	Shimomura, Yoshikazu: 14 articles (03/2015 - 01/2002)
5.	Baudouin, C: 13 articles (12/2011 - 03/2001)
6.	Cursiefen, Claus: 12 articles (10/2015 - 12/2007)
7.	Nishida, Teruo: 11 articles (11/2015 - 04/2004)
8.	Baudouin, Christophe: 10 articles (01/2015 - 11/2002)
9.	Inoue, Kenji: 10 articles (01/2015 - 03/2003)
10.	Kinoshita, Shigeru: 9 articles (09/2015 - 04/2006)

Related Diseases

1.	Allergic Conjunctivitis (Giant Papillary Conjunctivitis) 11/01/2013 - "There was a significant reduction (mean difference, -61.16; 95% CI, -101.61 to -20.72; I(2) = 58%) in the use of steroid eye drops in patients with steroid-dependent allergic conjunctivitis. " 03/01/2008 - "The aim of this study was to evaluate the efficacy of Lactobacillus Acidophilus eye-drops in controlling signs and symptoms of vernal keratoconjunctivitis (VKC). " 03/01/2004 - "The aim of the study was to evaluate the occurrence of ocular adverse effects observed after administration of anti-allergic eye drops with and without a preservative in patients with allergic conjunctivitis. " 04/01/2003 - "To study the capability of nine antiallergic eyedrops commonly used in the treatment of allergic conjunctivitis to inhibit complement activation induced in vitro by pollutants. " 12/01/2015 - "Does allergic conjunctivitis always require prescription eyedrops?"
2.	Keratitis 01/01/2010 - "Despite existing evidence to suggest that the eye drops are effective in the treatment of fungal keratitis, more studies are needed, especially in relation to using the eye drops as first-line and stand-alone treatment, preparation of higher concentrations, and optimal dosing frequency." 03/01/2008 - "The AS eye drops application improved significantly the values of the Schirmer test, detritus and superficial punctate keratitis as well. " 05/01/1999 - "The findings in this pilot study suggest that HSV stromal keratitis can be treated successfully with CsA eyedrops, especially in non-necrotizing disease. " 02/01/1987 - "These results indicate that 2'NDG may be therapeutically effective in treatment of herpes keratitis, and further suggest that for use as eye drops or in an ophthalmic insert, 2'NDG may be effective even if applied once per day." 10/01/2011 - "The efficacy of 0.1% MCFG eye-drops appears to be comparable with that of 0.2% FCZ eye-drops in the treatment of Candida fungal keratitis."
3.	Cataract (Cataracts) 09/01/2015 - "The ability of SkQ1 eye drops to slow down the cataract development is demonstrated on the senescence-accelerated OXYS rats: the SkQ1 treatment leads to the considerable improvement of the lens condition as compared to the control group. " 09/01/2009 - "Eyedrops containing FGLM-amide and SSSR were effective for the prevention of SPK after cataract surgery in diabetic patients." 12/01/2001 - "To evaluate safety and antiinflammatory efficacy of placing two Surodex (Oculex Pharmaceuticals, Inc., Sunnyvale, CA) in the eye after cataract surgery in comparison with steroid eyedrops and to compare anterior versus posterior chamber placement. " 02/01/2015 - "The aim of the present study was the histomorphological examination of the influence of SkQ1 eye drops on the cataract development in OXYS rats. " 01/01/2015 - "This study aimed to evaluate the cost of Mydriasert compared with conventional mydriatic eye drops to induce pupil dilation prior to cataract surgery using a budget impact model. "
4.	Inflammation 09/01/2004 - "Experimental evidence has established the efficacy of corticosteroid eyedrops in treating intraocular inflammation. " 08/01/1998 - "Advances in therapy include improved nonpreserved artificial tears and therapies targeted at decreasing ocular surface inflammation." 09/01/2003 - "Based on the findings of these studies, which indicate that the preservative causes increased synthesis of PGs and other substances and intensified postoperative inflammation, the term pseudophakic preservative maculopathy is proposed for CME caused by antiglaucoma eyedrops." 09/01/2015 - "In most instances, the eye inflammation responds well to corticosteroid and mydriatic eye drops and without the need for additional therapy. " 06/01/2015 - "Here, we show using aged mice that 2-Hydroxypropyl-β-cyclodextrin, a sugar molecule given as eye drops over 3 months results in significant reductions in Aβ by 65% and inflammation by 75% in the aged mouse retina. "
5.	Glaucoma 06/01/2007 - "Because the efficacy of both drugs was equivalent, with an identical safety profile, the long-acting eye drops seem to be an efficacious formulation for clinical use in Japanese glaucoma patients." 01/01/2008 - "This study indicates that easily comprehensible patient education on the use of eye drops, the nature of glaucoma and the proper use of prescribed drugs is vital to improving the clinical efficacy of topical ophthalmic medication of glaucoma in adult patients." 08/01/1991 - "Preservative-free beta-blocking eye drops are a real improvement in the therapy of glaucoma patients with irritated eyes." 03/01/2015 - "The purpose of this study was to evaluate the stabilty of precorneal tear film in glaucoma patient prior and after administration of lubricant eye drops with different tipe of preservatives. " 02/01/2015 - "This study underlines the importance of hygienic handling of eyedrops and raises the question of whether single-use glaucoma medication might be preferred to reduce the risk of contamination."

Related Drugs and Biologics

1.	Cyclosporine (Ciclosporin)
2.	Dexamethasone (Maxidex)
3.	Ophthalmic Solutions (Eye Drops)
4.	Diclofenac (SR 38)
5.	Gentamicins (Gentamicin)
6.	Tobramycin (Nebcin)
7.	N-acetylcarnosine
8.	lodoxamide ethyl (lodoxamide)
9.	Mitomycin (Mitomycin-C)
10.	Ketotifen (Ketotifene)

Related Therapies and Procedures

1.	Trabeculectomy (Trabeculoplasty)
2.	Phacoemulsification
3.	Injections
4.	Contact Lenses
5.	Topical Administration