Nitrogen Dioxide

Nitrogen oxide (NO2). A highly poisonous gas. Exposure produces inflammation of lungs that may only cause slight pain or pass unnoticed, but resulting edema several days later may cause death. (From Merck, 11th ed) It is a major atmospheric pollutant that is able to absorb UV light that does not reach the earth's surface.

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Networked: 578 relevant articles (2 outcomes, 100 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	McConnell, Rob: 8 articles (11/2014 - 02/2002)
2.	Künzli, Nino: 7 articles (07/2015 - 12/2006)
3.	Brunekreef, Bert: 7 articles (03/2015 - 09/2012)
4.	Jerrett, Michael: 7 articles (04/2014 - 05/2009)
5.	Poynter, Matthew E: 7 articles (05/2013 - 12/2002)
6.	Burnett, Richard T: 7 articles (01/2010 - 11/2003)
7.	Lurmann, Fred: 6 articles (11/2014 - 10/2003)
8.	Lebedeva, E S: 6 articles (09/2014 - 03/2010)
9.	Kuzubova, N A: 6 articles (09/2014 - 03/2010)
10.	Stieb, David M: 6 articles (04/2014 - 06/2004)

Related Diseases

1.	Pulmonary Edema 01/01/2011 - "To establish the rats model of acute pulmonary edema induced by inhalation of high concentrations of nitrogen dioxide (NO2). " 01/01/2011 - "[Establishment of acute pulmonary edema model induced by high concentrations of nitrogen dioxide in rats]." 11/01/2010 - "[Preliminary experimental research on glucocorticoid for treatment of nitrogen dioxide induced acute pulmonary edema in rats]." 02/01/1999 - "[Pulmonary edema caused by nitrogen dioxide inhalation]." 07/01/1994 - "[Biochemical mechanisms of developing toxic pulmonary edema upon exposure to nitrogen dioxide]."
2.	Adult Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 10/01/1998 - "Acute respiratory distress syndrome following nitrogen dioxide exposure." 03/01/2003 - "Exposure of intensive care unit nurses to nitric oxide and nitrogen dioxide during therapeutic use of inhaled nitric oxide in adults with acute respiratory distress syndrome." 10/01/2009 - "Inhalation of nitric acid fumes and its decomposition gases such as nitrogen dioxide results in delayed onset of acute respiratory distress syndrome. "
3.	Asthma (Bronchial Asthma) 01/01/2012 - "In this study, we analysed the association between environmental nitrogen dioxide (NO(2)) exposure and single nucleotide polymorphisms (SNP) in NFE2L2 and KEAP1 genes and their common impact on asthma risk. " 05/01/2006 - "The purpose of this study was to investigate dose-response relationships between asthma symptoms and indoor nitrogen dioxide (NO2) and house dust mite allergen (HDM) in children. " 12/01/2005 - "Although elevated nitrogen dioxide (NO2) exposures may exacerbate asthma, few studies have examined indoor NO2 levels in low-income, urban neighborhoods, where asthma prevalence is high. " 03/01/2005 - "Using a case-control design both easy to use and manage, the study confirms the significant association between hospital emergency admissions for asthma and exposure to nitrogen dioxide and total suspended particulate pollutants." 02/01/2004 - "Previous studies do not provide a clear picture of the relationship between nitrogen dioxide (NO(2)) exposure and asthma. "
4.	Infection 03/01/1989 - "To determine if there is scientific evidence for the possible relation of nitrogen dioxide exposure to human respiratory infection, our studies were performed to assess the impact of nitrogen dioxide on respiratory tract susceptibility to initial, or primary, infection, as well as to recurrent infection, or reinfection, with the identical virus. " 11/01/1988 - "The investigations in animals suggest a relationship between nitrogen dioxide and increased susceptibility to respiratory infection, but studies in which functional parameters of host resistance to such infections have been used are few. " 01/01/1988 - "The interaction between nitrogen dioxide (NO2) exposure and human susceptibility to respiratory virus infection was investigated in a placebo-controlled, randomized, blinded trial that was conducted in an environmentally controlled research chamber over a three-year period. " 07/01/1980 - "[An ultrastructural study on pathologic alterations and early response to infection due to Klebsiella pneumoniae in the lungs of mice exposed to nitrogen dioxide (author's transl)]." 02/01/2004 - "Nitrogen dioxide is not associated with respiratory infection during the first year of life."
5.	Respiratory Tract Infections (Respiratory Tract Infection) 01/01/2013 - "Temperature, nitrogen dioxide, circulating respiratory viruses and acute upper respiratory infections among children in Taipei, Taiwan: a population-based study." 02/01/2004 - "Nitrogen dioxide (NO(2)) has been related to respiratory infections in experimental studies but its role remains controversial in general population studies of children. " 06/01/1993 - "Between January 1988 and June 1990, 1,315 infants were enrolled into the study at birth and followed with prospective surveillance for the occurrence of respiratory infections and monitoring of nitrogen dioxide concentrations in their homes. " 09/01/1989 - "Laboratory and human studies have raised concern that exposure to nitrogen dioxide may increase the frequency and severity of respiratory infections in children and adults. " 06/01/1993 - "We have carried out a prospective cohort study to test the hypothesis that exposure to nitrogen dioxide increases the incidence and severity of respiratory infections during the first 18 months of life. "

Related Drugs and Biologics

1.	Ozone
2.	Gases
3.	Nitric Acid
4.	Emetine
5.	Cycloheximide (Cicloheximide)
6.	Particulate Matter
7.	Carbon Monoxide
8.	Sulfur Dioxide
9.	Air Pollutants (Pollutants, Air)
10.	Smoke

Related Therapies and Procedures

1.	Mechanical Ventilators (Ventilator)
2.	Lung Transplantation
3.	Power Plants
4.	Decompression
5.	Cardiopulmonary Bypass (Heart-Lung Bypass)