Nitrofurazone (Nitrofural)

A topical anti-infective agent effective against gram-negative and gram-positive bacteria. It is used for superficial WOUNDS AND INJURIES and skin infections. Nitrofurazone has also been administered orally in the treatment of TRYPANOSOMIASIS.

Also Known As:

Networked: 206 relevant articles (7 outcomes, 10 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1.	Bayat, Mohammad: 8 articles (09/2011 - 02/2005)
2.	Vasheghani, Mohammad Mehdi: 5 articles (12/2009 - 02/2005)
3.	Khoshvaghti, Amir: 2 articles (09/2011 - 10/2010)
4.	Ezzati, Ali: 2 articles (10/2010 - 01/2009)
5.	Krishna, V: 2 articles (08/2010 - 08/2009)
6.	Schumm, K: 2 articles (01/2008 - 01/2008)
7.	Lam, T B L: 2 articles (01/2008 - 01/2008)
8.	Doi, Kunio: 2 articles (04/2005 - 11/2003)
9.	Ito, Kyoko: 2 articles (04/2005 - 11/2003)
10.	Tuo, Xiaoye: 1 article (04/2015)

Related Diseases

1.	Wounds and Injuries (Trauma) 10/01/2013 - "Topical treatment with the EO (1%) increased the wound contraction from the third day of treatment (compared with nitrofurazone 0.2%), while systemic treatment (50 mg/kg/day) increased granulation tissue formation and reduced the water content. " 04/01/2012 - "Each wound of mice test group were treated topically with 50 microL of 0.1% natural or compounded DS black mud or 50 microL of 0.2% nitrofurazone once a day for 2 consecutive days and the mice control group were left untreated. " 01/01/2012 - "Healing was assessed by the rate of wound contraction in skin wound sites in rats treated with simple ointment base, 10% (w/w) LJEE ointment, or the reference standard drug, 0.2% (w/w) nitrofurazone ointment. " 12/01/2011 - "The parameters studied were tensile strength on incision wound model and in terms of wound contraction for excision wound model were compared with standard Nitrofurazone (NFZ) ointment (0.2% w/w). " 09/01/2009 - "The Nitrofurazone ointment treated group showed a significant (p < 0.001) reduction in the wound breaking strength when compared to control group in incision type of wound model. "
2.	Infection 09/01/1983 - "Human Antitetanus toxin and Pseudomonas hyper Immune globulin seem to have a definite role in the prevention and control of infection with Clostridium tetani and Pseudomonas aeruginosa 'Furacin' was found to be a valuable topical agent." 01/01/1979 - "After collection, the uteri were infused with nitrofurazone to reduce the chances of infection due to the procedure. " 03/01/1970 - "Nitrofurazone in the treatment of bacterial ear infections: re-evaluation after twenty years." 09/01/1959 - "The effect of nitrofurazone on Trypanosoma rhodesiense infections in mice." 02/01/1954 - "Nitrofurazone for the prevention of experimentally induced Eimeria tenella infections in chickens."
3.	Urinary Tract Infections (Urinary Tract Infection) 09/01/2004 - "The efficacy of nitrofurazone-coated urinary catheter in inhibitory activity of catheter-associated urinary tract infection (CAUTI) was evaluated. " 09/01/2004 - "A comparative multicentre study on the incidence of catheter-associated urinary tract infection between nitrofurazone-coated and silicone catheters." 09/01/2012 - "In vitro comparison of nitrofurazone- and silver alloy-coated foley catheters for contact-dependent and diffusible inhibition of urinary tract infection-associated microorganisms." 12/01/1999 - "The in vitro inhibitory activity of a nitrofurazone-coated urinary catheter (NFC) against 86 recently obtained susceptible and multidrug-resistant (MDR) clinical isolates of Escherichia coli, Klebsiella pneumoniae, Citrobacter freundii, Staphylococcus aureus, coagulase-negative staphylococci, and Enterococcus faecium, which are species implicated in catheter-associated urinary tract infection and which traditionally have been susceptible to nitrofuran derivatives, was determined using an agar diffusion assay. " 12/01/1999 - "Activities of a nitrofurazone-containing urinary catheter and a silver hydrogel catheter against multidrug-resistant bacteria characteristic of catheter-associated urinary tract infection."
4.	Wound Infection (Wound Infections) 10/01/1953 - "Treatment of wound infections with furacin soluble powder." 01/01/1983 - "This paper discusses the use of nitrofurazone in the treatment, or prophylaxis, of wound infection, various pyodermas and second and third degree burns, as well as its prophylactic use in skin grafting and donor sites. " 02/01/2008 - "This work was conducted to study the prophylactic efficacy of 2 topical antibiotic ointments (mupirocin and nitrofurazone) against wound infection in experimental contaminated crush wounds. "
5.	Inflammation 01/01/2013 - "Additionally, the histopathological results demonstrated that there was inflammation in Nitrofurazone group through twelveth day, somehow the epithelium was formed and abundant vessels were visible. " 06/25/1956 - "[Furacin in the treatment of inflammations of the lower segment of the urinary tract]." 01/01/2004 - "In addition to clinical picture of acute purulent maxillary inflammation (APMI), radionuclide tests data were examined to assess maxillary clearance by function of mucociliary system and forced nasal breathing in APMI patients treated with sodium chloride (crystalline and liquid) or furacin. " 01/01/2008 - "LLLT on the experimental third-degree burns significantly increased the total number of mast cells during the inflammation phase of wound healing; also, topical application of 0.2% nitrofurazone ointment on the same burns significantly increased the total number of mast cells during the proliferation phase of burn healing." 12/01/1994 - "Treatment consisting of stall confinement for 7 to 14 days, topical administration of a solution of furacin, dimethyl sulfoxide, glycerin, and prednisolone, and systemic administration of nonsteroidal anti-inflammatory drugs and corticosteroids was effective in controlling epiglottic edema and inflammation. "

Related Drugs and Biologics

1.	Nitrofurazone (Nitrofural)
2.	Hydrocortisone (Cortisol)
3.	Mupirocin (Bactroban)
4.	Ointments (Pastes)
5.	Suppositories (Vaginal Suppositories)
6.	Furazolidone (Furoxone)
7.	Nitrofurans
8.	Dimethyl Sulfoxide (DMSO)
9.	Prednisolone (Predate)
10.	Glycerol (Glycerine)

Related Therapies and Procedures

1.	Catheters
2.	Topical Administration
3.	Transplants (Transplant)
4.	Lasers (Laser)
5.	Drug Therapy (Chemotherapy)