Neurotic Disorders (Neuroses)

Disorders in which the symptoms are distressing to the individual and recognized by him or her as being unacceptable. Social relationships may be greatly affected but usually remain within acceptable limits. The disturbance is relatively enduring or recurrent without treatment.

Also Known As:

Networked: 533 relevant articles (18 outcomes, 28 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Mental Disorders (Mental Disorder)
2.	Personality Disorders (Personality Disorder)
3.	Depressive Disorder (Melancholia)
4.	Anxiety Disorders (Anxiety Disorder)
5.	Psychotic Disorders (Schizoaffective Disorder)

Experts

1.	Leichsenring, Falk: 3 articles (01/2007 - 10/2002)
2.	Skurikhin, E G: 3 articles (11/2005 - 04/2000)
3.	Cooke, Lara: 2 articles (05/2018 - 03/2016)
4.	Duncan, Diane: 2 articles (05/2018 - 03/2016)
5.	Pringsheim, Tamara: 2 articles (05/2018 - 03/2016)
6.	Symonds, Chris: 2 articles (05/2018 - 03/2016)
7.	D'Arcy, Carl: 2 articles (12/2012 - 07/2012)
8.	Kou, Changgui: 2 articles (12/2012 - 07/2012)
9.	Meng, Xiangfei: 2 articles (12/2012 - 07/2012)
10.	Shi, Jieping: 2 articles (12/2012 - 07/2012)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Neurotic Disorders:

1.	Antidepressive Agents (Antidepressants)IBA 12/01/1995 - "[Antidepressive agents and neuroses]." 04/01/1993 - "Increases in prescriptions for antidepressants were particularly evident for male patients, young adult patients, and patients with neurotic disorders. " 04/01/1990 - "Therefore neuroses may be treated effectively with antidepressants." 02/06/1987 - "Treatment of neuroses with antidepressive agents]." 11/01/1981 - "[Personality, antidepressant and neuroses]."
2.	Diazepam (Valium)FDA LinkGeneric 01/01/1989 - "1. The therapeutic efficacy on several neuroses between CM6912 and diazepam (DZP) was comparatively investigated by means of intergroup comparison method in a double-blind trials. " 05/01/1975 - "[A controlled double-blind crossover study of the efficacy of mepiprazol (EMD 16.923) and of diazepam in the treatment of neurotic disorders]." 05/01/1975 - "After a preliminary encouraging trial of mepiprazol (EMD 16.923) on 8 patients, a double-blind cross-over study of mepiprazol and diazepam was performed in order to compare their effect in the treatment of neurotic disorders, particularly on various forms of anxiety." 05/01/1989 - "[Intro- and extraversion in patients with neuroses as factors differentiating the effect of diazepam on psychomotor function]." 11/01/1988 - "[Effect of diazepam on cognitive and psychomotor functions in patients with neuroses in relation to various anxiety levels]."
3.	BenzodiazepinesIBA 04/01/1988 - "Large scale trials in the neuroses indicate that benzodiazepines are ineffective in depression, and transiently and partially effective in anxiety. " 05/01/2009 - "Since the literature on benzodiazepine use in elderly patients with anxiety disorders is limited, a large cross-sectional review of psychotropic prescriptions in 796 patients with neurotic disorders (ICD-10) (age range=11-91 years) was conducted across 30 sites in Japan. " 05/01/2011 - "The benzodiazepines became the most widely prescribed drugs worldwide, provided truly effective treatment for "minor forms" (neuroses) of mental disorders for the first time, increased the quality of scientific methodology in clinical research, and enabled the development of new etiopathogenic theories for anxiety disorders, especially after the discovery in 1977 of their high-affinity receptor complex." 11/01/1972 - "[Polygraphic studies of nocturnal sleep of subjects with phobic-obsessive neuroses treated with a new benzodiazepine (RO 5-3350)]." 05/13/1982 - "The anxiolytic activity of a new benzodiazepine derivative, bomazepam, was investigated in 30 ambulatory patients treated for psychotic or neurotic disorders. "
4.	Anti-Anxiety Agents (Anxiolytics)IBA 07/01/1982 - "Anxiolytics may be used in the neuroses and as adjuncts in other disorders (ex. " 05/13/1982 - "The anxiolytic activity of a new benzodiazepine derivative, bomazepam, was investigated in 30 ambulatory patients treated for psychotic or neurotic disorders. " 01/01/1982 - "The results of treatment of neurotic disorders with single or divided daily doses of the anxiolytic drug clobazam have been compared. " 01/01/2019 - "Specifically, they had significantly greater odds of being treated for neuroses (aOR 1.35; 95% CI 1.09-1.69) and having a prescription for anxiolytics/hypnotics (aOR 1.36; 95% CI 1.18-1.58) or antidepressants (aOR 1.35; 95% CI 1.17-1.55). " 01/01/2018 - "Ketamine is swiftly effective in a range of neurotic disorders that are resistant to conventional antidepressant and anxiolytic drugs. "
5.	Hypnotics and Sedatives (Sedatives)IBA 01/01/1959 - "[Physiology of the hypnotic state as an exact basis for the study of neuroses]." 04/01/1981 - "An experimental hypnotic approach to teaching the psychoanalytic theory of the neuroses: a brief communication." 01/01/2019 - "The long-term prescription was significantly associated with mood and neurotic disorder, cancer, prescription by psychiatrists, multiple prescriptions, hypnotics and medium half-life BZD in the initial prescription. " 11/01/1957 - "[Results of treatment of psychoneuroses & dysthymia with a new hypnotic-sedative preparation]." 01/01/1955 - "Treatment of psychoses and psychoneuroses with a new sedative (suavitil)."
6.	Opioid Analgesics (Opioids)IBA 01/01/2012 - "The prevalence and types of comorbid neurotic disorders among opioid-dependent patients in sustained full and partial remission are described." 09/01/2003 - "The objectives of this study were to assess the rate of neurotic disorders among opioid addicts, and reassess the rate of those neurotic disorders two weeks after complete detoxification of the patients. " 01/01/2012 - "[Comorbid neurotic disorders in opioid-dependent patients]." 09/01/2003 - "Present findings indicated that the rate of neurotic disorders in opioid dependants is high and (except for depression) was not significantly different before detoxification and two weeks after detoxification. "
7.	ethyl loflazepateIBA 01/01/1989 - "Comparison of therapeutic efficacy of neuroses between CM6912 (ethyl loflazepate) and diazepam in a double-blind trial."
8.	CatecholaminesIBA 09/01/1981 - "[Catecholamine metabolism in men with neuroses]." 01/01/1986 - "Comparison of the clinical findings with the results of dynamic assays for peripheral levels of acetylcholine and catecholamine in dogs exposed to special psychogenic and physiogenic impacts has helped to form an understanding about some common mechanisms of the formation of neuroses and neurosis-like states. " 05/01/1983 - "Effect of a test with administration of 0.1 g L-DOPA, reflecting the synthetic processes in sympathoadrenal system and its reactivity, on dynamics of catecholamine and DOPA excretion with urine was studied in patients with neuroses and neurosis-like states, namely, in women with climacteric syndrome, in men with sexual deteriorations, in patients with general neuroses and in patients with initial manifestations of brain circulation insufficiency. " 08/01/1984 - "[Catecholamine concentration and adenyl cyclase and phosphodiesterase activities of the sarcolemma of myocardial cells during hypokinesia and in experimental information neuroses]." 01/01/1985 - "The 24-hour pattern of prolactin, cortisol and growth hormone (GH) secretion, and the diurnal variations of plasma catecholamine levels, were tested in a sample of DSM III schizophrenics and in a control population of patients hospitalized in the same ward and diagnosed as suffering from neurotic disorders. "
9.	AntioxidantsIBA 03/01/1997 - "The positive results on treatment of the experimental and clinical neuroses with antioxidants which have antihypoxic properties are presented. " 09/01/1992 - "Is demonstrated a high efficiency of prophylaxis and therapy of neuroses using the anti-oxidants of anti-hypoxic action."
10.	Acetylcholine (Acetylcholine Chloride)FDA Link 06/26/1954 - "Intravenous acetylcholine in treatment of the neuroses." 01/01/1986 - "Comparison of the clinical findings with the results of dynamic assays for peripheral levels of acetylcholine and catecholamine in dogs exposed to special psychogenic and physiogenic impacts has helped to form an understanding about some common mechanisms of the formation of neuroses and neurosis-like states. "

Therapies and Procedures

1.	Therapeutics 01/01/2015 - "Intensive, short-term group psychotherapy with elements of individual therapy is an effective treatment for neurotic disorders. " 01/01/1990 - "An individual approach, comprehensive use of the treatment methods, drug-free therapy developed at the Clinic of Neuroses are based on a profound study of the neurohormonal, immunological and psychological status of patients." 08/01/1984 - "Cost-benefit analysis of a controlled trial of nurse therapy for neuroses in primary care." 05/01/1961 - "[A study of the effect of the Morita therapy of neuroses as evaluated by the Rorschach Test]." 01/01/2017 - "In patients with neuroses, improvement was more considerable in the short-term therapy groups during the first year of follow-up, and in higher level borderline patients LPP was more effective after 3 years of follow-up. "
2.	Laughter Therapy 01/01/2018 - "To evaluate the efficacy of gelototherapy (laughter therapy) in the complex treatment of borderline (neurotic) disorders. "
3.	Acupressure (Shiatsu) 01/01/2003 - "[Efficacy of acupressure therapy in combined treatment of psycho-autonomic neurotic disorders in children]."
4.	Aftercare (After-Treatment) 01/01/1979 - "At 2 1/2 to 5 years after treatment at a psychiatric hospital, 68 of the 100 patients followed up were considered improved: 60% were of upper socioeconomic status, 64% were men, and 72% had received diagnoses of psychoneuroses or personality disorders."
5.	Ambulatory Care (Outpatient Care) 12/01/1986 - "[Chronification of neuroses--on the critical phase of the inpatient-ambulatory care transition]." 03/01/1973 - "[Incidence of functional and neurotic disorders in rural ambulatory care]." 05/12/1979 - "Because outpatient care is more economical of time and personnel it should be preferred to psychiatric day care for many neurotic disorders." 08/01/2001 - "This study deals with the utilization of in- and outpatient care due to non-psychotic/non-organic disorders (ICD-9 300-307: neuroses, personality disorders, sexual disturbances, alcohol and substance dependencies, drug abuse and functional disorders). "