Neuropeptides

01/01/2015 - "A rat model of trigeminal pain, utilizing tongue jerks evoked by electrical tooth pulp stimulation during perfusion of the cerebral ventricles with various neuropeptide solutions, can be used in the pharmacological studies of nociception in orofacial area. "
10/01/2010 - "Interesting findings in an initial clinical study of neuropeptides and pain."
09/01/2009 - "The results obtained show that the method provides adequate figures of merit to support targeted peptidomic studies aimed to determine neuropeptide regulation in animal neuropathic and chronic pain models."
12/12/2007 - "This study was designed to understand how neurons integrate these two signals to regulate the neuropeptide important for inflammatory pain. "
04/01/2005 - "Recent studies have demonstrated that pulpal pain can induce neurogenic inflammatory reactions in gingiva and the expression of pro-inflammatory neuropeptides in gingival crevicular fluid (GCF). "

11/20/2009 - "In this study we report an improved protocol that combines simplified sample preparation and micro-scale separation for mass spectrometric analysis of neuropeptides from individual neuroendocrine organs of crab Cancer borealis. "
10/08/2013 - "This study evaluated sequence coverage of different size neuropeptides in two crustacean species, blue crab Callinectes sapidus and Jonah crab Cancer borealis using conventional MS methodologies and revealed limitations to mid- and large-size peptide analysis. "
09/01/2001 - "In regard to factors predictive of patient prognosis expression of the 3 neuropeptides in tumor cells, Gleason score, tumor stage and PSA were closely related to patient survival in this study The growth of hyperplastic prostate tissue is related to neuroendocrine cell activity. "
03/01/1999 - "Recent studies emphasize the participation of neuropeptides in the control of organogenesis in embryonal, fetal and early postnatal periods as well as in tumor growth control. "
08/01/1994 - "This study was conducted to define the distribution of nerves and neuropeptides around these tumors. "

06/30/1999 - "Results of animal studies as well as those of clinical studies suggest that these neuropeptides may be beneficial in aging, neuropathy, memory disturbances and schizophrenia. "
01/01/2007 - "Finally, the only compounds that act directly on neuropeptide systems that have demonstrated therapeutic efficacy in schizophrenia are neurokinin receptor antagonists. "
11/01/1987 - "Recently much interest has been shown in the antipsychotic efficacy of neuroleptic-like neuropeptides in schizophrenia. "
11/01/1987 - "[Antipsychotic efficacy of neuroleptic neuropeptides in schizophrenia. "
04/01/2012 - "This study demonstrates, for the first time, a significant genetic association of these neuropeptides with schizophrenia and strongly supports this hypothesis. "

10/01/2014 - "This data suggests that some neuropeptides may play a beneficial role following stroke, whilst others such as SP are deleterious."
12/01/2013 - "Although CSD can also worsen strokes, this brief paper has excluded the possible connection between the neuropeptide and CSD associated with them. "
10/13/1997 - "Increases in immunoreactivity were observed in nerve terminals and fibers; changes in the neuropeptides were maximal 3 days after stroke. "
03/01/1992 - "Changes of neuropeptides and their receptors in experimental stroke gerbil brains."
03/01/1983 - "Neuropeptides and stroke: current status and potential application."

01/01/2013 - "Neuropeptide S (NPS) increasingly emerges as a potential novel treatment option for anxiety diseases like panic and posttraumatic stress disorder. "
05/01/2012 - "Experiments in rodents revealed neuropeptide S (NPS) to constitute a potential novel treatment option for anxiety diseases such as panic and post-traumatic stress disorder. "
06/01/2013 - "We also link specific symptoms of human PTSD with extant findings in the NPY field to reveal potential physiological contributions of the neuropeptide to the disorder. "
01/01/2015 - "Based on previous findings, we also examined whether intranasal delivery of neuropeptide S (NPS), which increasingly emerges as a potential novel treatment option for anxiety symptoms occurring in a variety of diseases like anxiety disorders, posttraumatic stress disorder, and major depression, impacts on the high-anxiety electrophysiological endophenotype in HAB mice. "
02/01/2012 - "In addition, the potential efficacy of targeting neuropeptide systems that have been implicated in stress responses and stress system neuroadaptation in order to treat comorbid PTSD and substance abuse will be discussed. "