Neurocirculatory Asthenia

A clinical syndrome characterized by palpitation, SHORTNESS OF BREATH, labored breathing, subjective complaints of effort and discomfort, all following slight PHYSICAL EXERTION. Other symptoms may be DIZZINESS, tremulousness, SWEATING, and INSOMNIA. Neurocirculatory asthenia is most typically seen as a form of anxiety disorder.
Also Known As:
Asthenia, Neurocirculatory; Asthenias, Neurocirculatory; Cardiac Neuroses; Heart Syndrome, Hyperkinetic; Neurocirculatory Asthenias; Neuroses, Cardiac; Neurosis, Cardiac; Syndrome, Effort; Syndrome, Hyperkinetic Heart; Cardiac Neurosis; Effort Syndrome; Hyperkinetic Heart Syndrome
Networked: 65 relevant articles (1 outcomes, 5 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Neurocirculatory Asthenia
2. Hypertension (High Blood Pressure)
3. Thyrotoxicosis
4. Mitral Valve Prolapse
5. Persian Gulf Syndrome (Gulf War Syndrome)


1. Engel, Charles C: 2 articles (01/2004 - 01/2004)
2. Lu, Yu-Ying: 1 article (06/2008)
3. Mu, Guang-Mei: 1 article (06/2008)
4. Nguyen, Lim: 1 article (12/2007)
5. Hinton, Devon E: 1 article (12/2007)
6. Pollack, Mark H: 1 article (12/2007)
7. Hinton, Ladson: 1 article (12/2007)
8. Hsia, Curtis: 1 article (12/2007)
9. Tran, Minh: 1 article (12/2007)
10. Nguyen, Men: 1 article (12/2007)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Neurocirculatory Asthenia:
1. Diazepam (Valium)FDA LinkGeneric
2. Bisoprolol (Concor)FDA LinkGeneric
3. Irritable heartIBA
01/01/2004 - "These syndromes have gone by a variety of names such as Da Costa's syndrome, irritable heart, shell shock, neurocirculatory asthenia, and battle fatigue. "
11/01/1982 - "the study of which is equally interesting to the civil practitioner" was described in his 1871 paper "On Irritable Heart; A Clinical Study of a Form of Functional Cardiac Disorder and Its Consequences." Soon labeled DaCosta's syndrome, the irritable heart lineage can be traced through the soldier's heart, the effort syndrome, and neurocirculatory asthenia in World War I, anxiety neurosis in World War II, and the mitral valve prolapse syndrome in the second half of the 20th century."
12/01/2007 - "Viewed historically and cross-culturally, orthostatic-induced dizziness, i.e., dizziness caused by standing up from a sitting or a lying position, forms a key aspect of many syndromes: irritable heart (American Civil War), effort syndrome (World War I and World War II), chronic fatigue syndrome (contemporary USA), Gulf War syndrome (contemporary USA), and orthostatic dysregulation (contemporary Japan). "
01/01/2004 - "The 20th century offered many examples of post-war syndromes such as Da Costa's syndrome, irritable heart, shell shock, effort syndrome, medical evacuation syndrome, post-traumatic stress disorder, and Gulf War syndrome. "
09/01/1983 - "Various labels such as "effort syndrome," "anxiety neurosis," "neurocirculatory asthenia," "vasoregulatory asthenia," and "irritable heart," have been employed over the past century to describe this syndrome. "
4. Norepinephrine (Noradrenaline)FDA LinkGeneric
5. Thiamine PyrophosphateIBA
6. Epinephrine (Adrenaline)FDA LinkGeneric
7. Keto AcidsIBA
8. GasesIBA
9. ElectrolytesIBA
10. Propranolol (Inderal)FDA LinkGeneric

Therapies and Procedures

1. Baths
2. Ear Acupuncture
3. Gamma Cameras (Gamma Camera)
4. Thyroidectomy
5. Climatotherapy