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Neural Tube Defects (Exencephaly)

Congenital malformations of the central nervous system and adjacent structures related to defective neural tube closure during the first trimester of pregnancy generally occurring between days 18-29 of gestation. Ectodermal and mesodermal malformations (mainly involving the skull and vertebrae) may occur as a result of defects of neural tube closure. (From Joynt, Clinical Neurology, 1992, Ch55, pp31-41)
Also Known As:
Exencephaly; Diastematomyelia; Iniencephaly; Neural Tube Defect; Craniorachischisis; Acrania; Developmental Neural Tube Defects; Neural Tube Developmental Defects; Neuroenteric Cyst; Occult Spinal Dysraphism; Occult Spinal Dysraphism Sequence; Tethered Spinal Cord Syndrome; Acranias; Craniorachischises; Cyst, Neurenteric; Cyst, Neuroenteric; Cysts, Neurenteric; Cysts, Neuroenteric; Defect, Neural Tube; Defects, Neural Tube; Diastematomyelias; Dysraphism, Occult Spinal; Dysraphisms, Occult Spinal; Exencephalies; Iniencephalies; Myelodysplasia, Spinal Cord; Myelodysplasias, Spinal Cord; Neurenteric Cysts; Neuroenteric Cysts; Occult Spinal Dysraphisms; Spinal Cord Myelodysplasias; Spinal Dysraphism, Occult; Spinal Dysraphisms, Occult; Tethered Cord Syndromes; Developmental Defects, Neural Tube; Neurenteric Cyst; Spinal Cord Myelodysplasia; Tethered Cord Syndrome
Networked: 4299 relevant articles (137 outcomes, 454 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Congenital Abnormalities (Deformity)
2. Neural Tube Defects (Exencephaly)
3. Spinal Dysraphism (Spina Bifida)
4. Congenital Heart Defects (Congenital Heart Defect)
5. Neoplasms (Cancer)

Experts

1. Ren, Aiguo: 69 articles (01/2022 - 11/2003)
2. Finnell, Richard H: 68 articles (01/2022 - 01/2002)
3. Li, Zhiwen: 56 articles (01/2022 - 06/2005)
4. Jin, Lei: 45 articles (01/2022 - 08/2011)
5. Zhang, Ting: 45 articles (12/2021 - 01/2008)
6. Greene, Nicholas D E: 36 articles (01/2022 - 02/2002)
7. Shaw, Gary M: 36 articles (01/2019 - 01/2002)
8. Wang, Linlin: 35 articles (01/2022 - 06/2013)
9. Molloy, Anne M: 35 articles (10/2021 - 01/2002)
10. Koren, Gideon: 34 articles (01/2020 - 01/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Neural Tube Defects:
1. Folic Acid (Vitamin M)FDA LinkGeneric
2. alpha-Fetoproteins (alpha-Fetoprotein)IBA
3. VitaminsIBA
4. Valproic Acid (Depakote)FDA LinkGeneric
5. Anticonvulsants (Antiepileptic Drugs)IBA
6. Inositol (Myoinositol)IBA
7. Glucose (Dextrose)FDA LinkGeneric
8. Methionine (L-Methionine)FDA Link
9. dolutegravirIBA
10. Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric

Therapies and Procedures

1. Induced Hyperthermia (Thermotherapy)
2. Art Therapy
3. Osteotomy
4. Catheters
5. Prenatal Care (Care, Prenatal)