Hormone-Dependent Neoplasms (Neoplasms, Hormone Dependent)

Certain tumors that 1, arise in organs that are normally dependent on specific hormones and 2, are stimulated or caused to regress by manipulation of the endocrine environment.

Also Known As:

Networked: 13 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Precocious Puberty
2.	Endometriosis (Adenomyosis)
3.	Fibroadenoma
4.	Endometrial Neoplasms (Endometrial Cancer)
5.	Porphyrias

Experts

1.	Nakamura, Noriaki: 1 article (05/2007)
2.	Tanaka, Shinji: 1 article (05/2007)
3.	Kawamura, Toru: 1 article (05/2007)
4.	Arii, Shigeki: 1 article (05/2007)
5.	Teramoto, Kenichi: 1 article (05/2007)
6.	Washio, Masakazu: 1 article (06/2005)
7.	Hayashi, Kyohei: 1 article (06/2005)
8.	Suzuki, Koji: 1 article (06/2005)
9.	Ozasa, Kotaro: 1 article (06/2005)
10.	Tamakoshi, Akiko: 1 article (06/2005)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Hormone-Dependent Neoplasms:

1.	HormonesIBA 04/10/1996 - "[Sex hormone substitution in hormone-dependent neoplasms--oil into the fire?]." 07/01/1979 - "The existence of five specific steroid receptors within a single tissue is unique and provides a novel model for studying the interrelated actions of all steroid hormones and their therapeutic responses in a hormone-dependent neoplasm." 01/01/1986 - "Clinical and experimental evidence indicates that carcinoid tumours of the stomach fundic mucosa represent another example of hormone-dependent neoplasm, gastrin being the hormone involved in tumour induction. "
2.	Estrogens (Estrogen)FDA Link 08/01/1999 - "[The significance of estrogen metabolism for hormone-dependent neoplasms from the clinical-pharmacological viewpoint]." 07/01/2003 - "Since a fibroadenoma is a benign hormone-dependent neoplasm which contains estrogen receptor (ER) levels higher than in the mammary lobule, an evaluation of the effect of this drug on the proliferative activity of both the epithelium and the stroma of fibroadenomas in premenopausal women following the administration of 10 or 20 mg/day over 22 days was proposed. " 05/01/2007 - "Hormone replacement therapy (HRT) containing estrogens is generally used to relieve climacteric symptoms and to prevent osteoporosis and coronary heart disease [1], however, there has been increasing evidence of the HRT as the risk of hormone-dependent neoplasms including breast cancer [2], uterine endometrial cancer [3], ovarian cancer [4], and even lung cancer [5]. "
3.	Gonadotropin-Releasing Hormone (GnRH)FDA Link 02/01/1986 - "Thus, GnRH analogs are an attractive class of compounds for achieving a medical castration in the treatment of hormone-dependent neoplasms. " 06/01/1985 - "These results show for the first time that antagonists of LH-RH can be administered by routes other than parenteral, increasing their potential clinical use in conditions in which inhibition of gonadotropins is desired, as in contraception and in therapy for endometriosis, precocious puberty, and hormone-dependent neoplasms."
4.	Phytoestrogens (Phytoestrogen)IBA 06/01/2005 - "Phytoestrogens may be associated with a reduced risk of hormone dependent neoplasms such as prostate and breast cancers. "
5.	Biological Markers (Surrogate Marker)IBA 01/01/1981 - "[Cyclic nucleotides and estrogen receptors as biologic markers in hormone-dependent neoplasms]."
6.	Steroid Receptors (Steroid Receptor)IBA 07/01/1979 - "The existence of five specific steroid receptors within a single tissue is unique and provides a novel model for studying the interrelated actions of all steroid hormones and their therapeutic responses in a hormone-dependent neoplasm."
7.	Estrogen ReceptorsIBA 01/01/1981 - "[Cyclic nucleotides and estrogen receptors as biologic markers in hormone-dependent neoplasms]."
8.	Cyclic NucleotidesIBA 01/01/1981 - "[Cyclic nucleotides and estrogen receptors as biologic markers in hormone-dependent neoplasms]."
9.	InterferonsIBA 03/15/1982 - "These results suggest that one of the mechanisms by which interferon treatment may affect the growth of hormone-dependent neoplasms could be the interaction with production and/or function of circulating hormonal compounds."
10.	GonadotropinsIBA 06/01/1985 - "These results show for the first time that antagonists of LH-RH can be administered by routes other than parenteral, increasing their potential clinical use in conditions in which inhibition of gonadotropins is desired, as in contraception and in therapy for endometriosis, precocious puberty, and hormone-dependent neoplasms."

Therapies and Procedures

1.	Contraception (Birth Control) 12/05/1987 - "These agents find application in contraception, the treatment of hormone-dependent neoplasms, precocious puberty, endometriosis, porphyria and disturbances of the menstrual cycle. " 06/01/1985 - "These results show for the first time that antagonists of LH-RH can be administered by routes other than parenteral, increasing their potential clinical use in conditions in which inhibition of gonadotropins is desired, as in contraception and in therapy for endometriosis, precocious puberty, and hormone-dependent neoplasms."
2.	Hormone Replacement Therapy (Therapy, Hormone Replacement) 05/01/2007 - "Hormone replacement therapy (HRT) containing estrogens is generally used to relieve climacteric symptoms and to prevent osteoporosis and coronary heart disease [1], however, there has been increasing evidence of the HRT as the risk of hormone-dependent neoplasms including breast cancer [2], uterine endometrial cancer [3], ovarian cancer [4], and even lung cancer [5]. "
3.	X-Ray Therapy 03/28/1959 - "[Roentgenotherapy complementary to endocrinosurgical operations in certain hormone-dependent neoplasms; experimental research & preliminary clinical results]."
4.	Castration 02/01/1986 - "Thus, GnRH analogs are an attractive class of compounds for achieving a medical castration in the treatment of hormone-dependent neoplasms. "