Neomycin

07/01/1977 - "There was a significant reduction in the incidence of infections in foals given neomycin and framomycin during the first 30 days of life."
07/01/2014 - "Infection assessed on detached calamondin leaves revealed that application of CaCl2 or neomycin 24 h prior to inoculation provided protection against Alt. "
06/01/1998 - "Our studies revealed that (i) a low-level rescue and autonomous replication of the wild-type AAV genome occurred in 293 but not in HeLa cells; (ii) mutations in the RBS resulted in augmented expression from the p5 promoter, leading to more efficient rescue and/or replication of the AAV genome in 293 but not in HeLa cells; (iii) little rescue and/or replication occurred from plasmids containing mutations in the YBS alone in the absence of coinfection with adenovirus; (iv) expression of the adenovirus E1A gene products was insufficient to mediate rescue and/or replication of the AAV genome in HeLa cells; (v) autonomously replicated AAV genomes in 293 cells were successfully encapsidated in mature progeny virions that were biologically active in secondary infection of HeLa cells in the presence of adenovirus; and (vi) stable transfection of recombinant AAV plasmids containing a gene for resistance to neomycin significantly affected stable integration only in 293 cells, presumably because rescue and autonomous replication of the AAV genome from these plasmids occurred in 293 cells but not in HeLa or KB cells. "
07/01/1997 - "Although the application of neomycin has been limited by its high toxicity, this study suggested that this drug might be useful as a topical agent for cutaneous infections by M. "
06/01/1979 - "Neomycin ointment is shown to be no more effective than placebo ointment in preventing site infection after biopsy according to a double-blind, placebo controlled study, analyzed according to an armitage restricted design, two-sided test, sequential analysis."

07/28/2001 - "Neomycin should not be used to treat hepatic encephalopathy."
12/01/1992 - "The time elapsed between the initiation of the therapeutic procedure and regression to grade zero of hepatic encephalopathy was 39.11 +/- 23.04 hours for the group of active neomycin, and 49.47 +/- 21.92 hours for the placebo group, but this difference did not achieve statistical significance."
12/01/1992 - "The therapy for hepatic encephalopathy consisted in the control of precipitating factors associated with 6 g of neomycin sulfate "per os" or placebo. "
12/01/1992 - "Over a period of five years, 102 cirrhotic patients developed hepatic encephalopathy at admission or during hospitalization, and 39 were randomized for treatment with either neomycin sulfate or placebo. "
12/01/1992 - "Double-blind randomized clinical trial comparing neomycin and placebo in the treatment of exogenous hepatic encephalopathy."

12/01/1992 - "Contact allergic external otitis may occur during long lasting local therapy with various substances including vehicles, the most common allergen being neomycin. "
07/01/1963 - "Neomycin undecylenate: combined antibacterial-antifungal therapy in otitis externa."
04/01/1956 - "[Attempted local therapy of otorrhea and external otitis with auricular instillations of neomycin]."
01/10/1966 - "Neomycin contact dermatitis superimposed on otitis externa."
04/09/1983 - "The miconazole cream proved as effective as the preparation containing neomycin in the first-line treatment of otitis externa. "

09/01/2011 - "The herbal formulation Jena(®) systematically designed and formulated based on two Ugandan medicinal plants is according to this study better than neomycin and probably other imported products for wound management in Uganda. "
05/01/2014 - "Furthermore, the wound healing potential and skin irritation activity of the formulated nanoemulsion in Wistar rats, suggested non-irritant and higher wound contraction rate with respect to control and neomycin treated rats. "
01/23/2014 - "Among the formulations, NaCMC wafer containing neomycin trisulphate exhibited the most desirable wound dressing characteristics (i.e., flexibility, sponginess, uniform wafer texture, high content drug uniformity) with the highest in vitro drug release and the greatest inhibition against both Gram positive and Gram negative bacteria. "
09/01/2011 - "The herbal formulation (Jena) had a significantly higher rate of wound closure than neomycin (p<0.05) which itself was better than distilled water. "
09/01/2011 - "The wounds were treated topically with distilled water (group I), Jena(®) (group II)and Neomycin sulfate cream (group III). "

05/01/2012 - "By early diagnosis, using triple-topical therapy (polyhexamid, propamidinisoethionat, neomycin) acanthamoeba keratitis often heals appropriately. "
01/01/1995 - "A combination of Brolene and Neomycin is the best approach in treating Acanthamoeba keratitis. "
05/01/1999 - "Propamidine isethionate and neomycin are an effective treatment for Acanthamoeba keratitis. "
05/01/1999 - "Results of a trial of combined propamidine isethionate and neomycin therapy for Acanthamoeba keratitis. "
12/01/2013 - "After early diagnosis acanthamoeba keratitis can often be successfully treated using triple topical therapy with polyhexamide, propamidine isethionate and neomycin. "