Naphthyridines

A group of two-ring heterocyclic compounds consisting of a NAPHTHALENES double ring in which two carbon atoms, one per each ring, are replaced with nitrogens.

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Debnath, Bikash: 1 article (11/2012)
2.	Ding, Jian: 1 article (11/2012)
3.	Kazemi, Roza: 1 article (11/2012)
4.	Long, Ya-Qiu: 1 article (11/2012)
5.	Neamati, Nouri: 1 article (11/2012)
6.	Odde, Srinivas: 1 article (11/2012)
7.	Sanchez, Tino W: 1 article (11/2012)
8.	Wang, Yong: 1 article (11/2012)
9.	Xie, Hua: 1 article (11/2012)
10.	Xu, Shili: 1 article (11/2012)

Related Diseases

1.

Neoplasms (Cancer) 11/26/2012 - "Further optimization of the 5,8-disubstituted-[1,6]naphthyridines with structural variation on 7-carboxamide delivered novel compounds with significant cytotoxicity in a panel of cancer cell lines and effective inhibition against select oncogenic kinases." 11/01/2007 - "Now, quinazoline related chemical classes such as quinolines and naphthyridines are being exploited in cancer chemotherapy and a number of molecules such as compounds EKB-569 (52), HKI-272 (78) and SNS-595 (127a) are in different phases of clinical trials. "

Related Drugs and Biologics

1.	Quinolines
2.	Quinazolines
3.	neratinib
4.	vosaroxin
5.	EKB 569
6.	Phosphotransferases (Kinase)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)