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Naphazoline (Clear, All)

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An adrenergic vasoconstrictor agent used as a decongestant.

Also Known As:

Clear, All; All Clear; Idril; Privin; Albalon; Nafazair; Naphcon forte; Vasocon; AK-Con; Abbot Brand of Naphazoline Hydrochloride; Afazol Grin; Akorn Brand of Naphazoline Hydrochloride; Alcon Brand 1 of Naphazoline Hydrochloride; Alcon Brand 2 of Naphazoline Hydrochloride; Allergan Brand of Naphazoline Hydrochloride; Bausch & Lomb Brand 1 of Naphazoline Hydrochloride; Bausch & Lomb Brand 2 of Naphazoline Hydrochloride; Chauvin Brand of Naphazoline Hydrochloride; Ciba Vision Brand 1 of Naphazoline Hydrochloride; Ciba Vision Brand 2 of Naphazoline Hydrochloride; Clear Eyes; Colirio Alfa; Febena Brand of Naphazoline Hydrochloride; Grin Brand of Naphazoline Hydrochloride; Iquinosa Brand of Naphazoline Hydrochloride; Miraclar; Naphazoline Hydrochloride; Naphazoline Monohydrochloride; Naphazoline Nitrate; Naphcon; Novartis Brand 1 of Naphazoline Hydrochloride; Novartis Brand 2 of Naphazoline Hydrochloride; Optazine; Optima Brand of Naphazoline Hydrochloride; Privine; Proculin; Ross Brand of Naphazoline Hydrochloride; Siozwo; Stulln Brand of Naphazoline Hydrochloride; Tele-Stulln; VasoNit; Vasoclear; Vasocon Regular; Vasoconstrictor Pensa; Warner-Lambert Brand of Naphazoline Nitrate; Whitehall Brand of Naphazoline Hydrochloride; Winzer Brand of Naphazoline Hydrochloride; AK Con; AKCon; Alfa, Colirio; Eyes, Clear; Grin, Afazol; Hydrochloride, Naphazoline; Monohydrochloride, Naphazoline; Nitrate, Naphazoline; Pensa, Vasoconstrictor; Regular, Vasocon; Tele Stulln; TeleStulln; Warner Lambert Brand of Naphazoline Nitrate; forte, Naphcon; 1H-Imidazole, 4,5-dihydro-2-(1-naphthalenylmethyl)-

Networked: 163 relevant articles (7 outcomes, 14 trials/studies)

Relationship Network

Drug Context: Research Results

Heterocyclic Compounds: 60
- 1-Ring Heterocyclic Compounds
  - Azoles: 413
    - Imidazoles: 107
      - Naphazoline: 163
        nafimidone: 5
        naphazoline mononitrate drug combination antazoline sulfate: 2
        nafimidone alcohol: 1
        Naphcon A: 1
        Twen Pantocaine-Privin

Experts

1.	Tickoo, Satish K: 2 articles (05/2014 - 06/2010)
2.	Reuter, Victor E: 2 articles (05/2014 - 06/2010)
3.	Press, Gregory M: 2 articles (04/2013 - 11/2012)
4.	Radecki, Ryan P: 2 articles (04/2013 - 11/2012)
5.	Chathampally, Yashwant G: 2 articles (04/2013 - 11/2012)
6.	Greenberg, Richard E: 2 articles (01/2013 - 06/2004)
7.	Uzzo, Robert G: 2 articles (01/2013 - 06/2004)
8.	Mizutani, Nobuaki: 2 articles (09/2006 - 01/2003)
9.	Trujillo Orcha, Natalia: 1 article (10/2015)
10.	Martinez López, Constancio: 1 article (10/2015)

Related Diseases

1.	Pruritus (Itching) 04/01/1990 - "The results of this study indicate that the combination of naphazoline and antazoline was more effective in inhibiting redness than naphazoline and more effective in inhibiting itching than antazoline. " 08/01/1980 - "In two independent studies including 25 subjects each, naphazoline caused significant whitening (but did not prevent itching) in the histamine-induced red, itchy eye. " 08/01/1980 - "The combination of naphazoline and antazoline produced significant whitening and inhibition of itching in all eyes challenged by histamine. " 04/01/1990 - "Vasocon-A was found to significantly inhibit all five major signs and symptoms of allergic conjunctivitis: itching, redness, chemosis, lid swelling, and tearing, for more than 85% of the comparisons when compared over time with placebo, naphazoline alone, or antazoline alone. " 08/01/1975 - "Evaluation of response at various times after instillation of medication for lacrimation, conjunctival inflammation, pruritus, photophobia and pain showed naphazoline hydrochloride, antazoline phosphate and the combination product superior to placebo. "
2.	Intermittent Claudication 01/01/2003 - "This paper deals with an open no incomparable study of the efficacy of vasonit retard in the treatment of intermittent claudication in patients suffering from arterial pathology. " 01/01/2003 - "Thus, talking into account the clinical evidence and the data supplied by instrumental diagnostic techniques, it is necessary to admit that vasonit retard is an effective drug for the treatment of patients suffering from intermittent claudication." 01/01/2003 - "[Vasonit retard in the treatment of intermittent claudication in patients with obliterating diseases of the lower extremities]."
3.	Blepharoptosis (Ptosis, Eyelid) 07/01/2011 - "Topical naphazoline was evaluated as useful in the treatment of myasthenic blepharoptosis by >70% of the patients. " 07/01/2011 - "We examined the efficacy of topical naphazoline in the treatment of myasthenic blepharoptosis. " 07/01/2011 - "Sixty MG patients with blepharoptosis (32 with ocular symptoms only and 28 with mild generalized symptoms) were enrolled in a multicenter open trial of topical naphazoline. " 07/01/2011 - "Topical naphazoline was found to be an effective supplementary symptomatic treatment for myasthenic blepharoptosis." 07/01/2011 - "Topical naphazoline in the treatment of myasthenic blepharoptosis."
4.	Infection 05/01/1992 - "Our results show that (i) infection starts at the fetal stage and is maintained throughout adulthood, and (ii) this chronic infection of the thymus can be eliminated by transfer of virus-specific cytotoxic T lymphocytes (CTL) that infiltrate the thymus and clear all viral products from both medullary and cortical regions. " 01/01/2015 - "To attain the goal of elimination in Namibia, systems are being strengthened to identify and clear all infections, and significantly reduce human-mosquito contact. " 08/01/2006 - ""It feels good to be told that I'm all clear": patients' accounts of retesting following genital chlamydial infection." 01/01/2004 - "For example, the pro-inflammatory response is quite limited, and with the exception of the type I interferons, it is not at all clear what innate responses are necessary to provide protection from acute infection. " 09/01/2009 - "vivax merozoite surface protein 1 (PvMSP1(19)), would have a delay in the time to reinfection following treatment to clear all blood-stage malaria infections. "
5.	Headache (Headaches) 01/01/2013 - "The observation that naphazoline detoxification relieved the patient's headache, indicates that prolonged use of naphazoline may cause chronic headaches. " 01/01/2013 - "However, the patient did not suffer from sinusitis, but from a medication overuse headache (ICHD-II 8.3; ICD-10 44.41) that appeared to be due to excessive use of naphazoline. " 01/01/2013 - "Nasal decongestant and chronic headache: a case of naphazoline overuse headache?" 09/01/2004 - "This is a case report of a 44-year-old man, without previous morbidities, who presented a sudden onset headache and arterial hypertension 24 hours after use of naphazoline as nasal decongestant. " 01/01/2011 - "After the surgery, information about changes in the quality of headache in patients with dominant contact points in preoperative nasal endoscopy whose headache responded to topical anaesthesia with lidocaine 2%+naphazoline 0.5% was collected over a 2-year follow-up. "

Related Drugs and Biologics

1.	Antazoline (Antazoline Phosphate)
2.	Yohimbine (Yocon)
3.	efaroxan
4.	Naphazoline (Clear, All)
5.	Fluorometholone (FML)
6.	olopatadine (Patanol)
7.	Ophthalmic Solutions (Eye Drops)
8.	Lidocaine (Xylocaine)
9.	Oxymetazoline
10.	Histamine (Histamine Dihydrochloride)

Related Therapies and Procedures

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2.	First Aid (Aids, First)
3.	Cholecystectomy
4.	Laser In Situ Keratomileusis (LASIK)
5.	Heterologous Transplantation (Xenotransplantation)