N-Formylmethionine (Formylmethionine, N)

Effective in the initiation of protein synthesis. The initiating methionine residue enters the ribosome as N-formylmethionyl tRNA. This process occurs in Escherichia coli and other bacteria as well as in the mitochondria of eucaryotic cells.

Also Known As:

Networked: 14 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	An, Jie: 1 article (03/2022)
2.	Bai, Xinshu: 1 article (03/2022)
3.	Dong, Xiushan: 1 article (03/2022)
4.	Hu, Tianjiao: 1 article (03/2022)
5.	Li, Hongxia: 1 article (03/2022)
6.	Liu, Shuai: 1 article (03/2022)
7.	Xue, Xin: 1 article (03/2022)
8.	Yang, Chuanli: 1 article (03/2022)
9.	Zhang, Yan: 1 article (03/2022)
10.	Bazzano, Lydia A: 1 article (01/2020)

Related Diseases

1.	Inflammation (Inflammations) 01/01/2004 - "The objectives of this study were to evaluate the [3H]PK11195 binding parameters in a model of acute inflammation, the N-formylmethionine-leucine-phenylalanine (fMLP)-stimulated neutrophil cell membranes, and to analyze if alterations of peripheral-type benzodiazepine receptor (PBR) characteristics occurred in neutrophil cell membranes of patients affected by osteoarthritis (OA), rheumatoid arthritis (RA), and psoriasic arthritis (PA). " 01/01/2017 - "Metabolites that were altered in highly significant manner in both included, for example, kynurenine, kynurenate, citrulline, and mannitol/sorbitol under inflammation (all elevated) plus lactate (elevated) and N-formylmethionine (depressed) for hypoxia. "
2.	Critical Illness (Critically Ill) 10/19/2022 - "Circulating N-formylmethionine and metabolic shift in critical illness: a multicohort metabolomics study." 10/19/2022 - "We hypothesized that in critically ill adults, the response to N-formylmethionine is associated with increases in metabolomic shift-related metabolites and increases in 28-day mortality. "
3.	Osteoarthritis 01/01/2004 - "The objectives of this study were to evaluate the [3H]PK11195 binding parameters in a model of acute inflammation, the N-formylmethionine-leucine-phenylalanine (fMLP)-stimulated neutrophil cell membranes, and to analyze if alterations of peripheral-type benzodiazepine receptor (PBR) characteristics occurred in neutrophil cell membranes of patients affected by osteoarthritis (OA), rheumatoid arthritis (RA), and psoriasic arthritis (PA). "
4.	Rheumatoid Arthritis 01/01/2004 - "The objectives of this study were to evaluate the [3H]PK11195 binding parameters in a model of acute inflammation, the N-formylmethionine-leucine-phenylalanine (fMLP)-stimulated neutrophil cell membranes, and to analyze if alterations of peripheral-type benzodiazepine receptor (PBR) characteristics occurred in neutrophil cell membranes of patients affected by osteoarthritis (OA), rheumatoid arthritis (RA), and psoriasic arthritis (PA). "
5.	Arthritis (Polyarthritis) 01/01/2004 - "The objectives of this study were to evaluate the [3H]PK11195 binding parameters in a model of acute inflammation, the N-formylmethionine-leucine-phenylalanine (fMLP)-stimulated neutrophil cell membranes, and to analyze if alterations of peripheral-type benzodiazepine receptor (PBR) characteristics occurred in neutrophil cell membranes of patients affected by osteoarthritis (OA), rheumatoid arthritis (RA), and psoriasic arthritis (PA). "

Related Drugs and Biologics

1.	Phenylalanine (L-Phenylalanine)
2.	Leucine (L-Leucine)
3.	GABA-A Receptors (GABA(A) Receptor)
4.	PK 11195 (PK11195)
5.	GTP-Binding Proteins (G-Protein)
6.	Peptides (Polypeptides)
7.	Guanine Nucleotides
8.	Pertussis Toxin
9.	Type C Phospholipases
10.	N-Formylmethionine Leucyl-Phenylalanine

Related Therapies and Procedures

1.	Punctures
2.	Ligation