Myxosarcoma

A sarcoma, usually a liposarcoma or malignant fibrous histiocytoma, with an abundant component of myxoid tissue resembling primitive mesenchyme containing connective tissue mucin. (Stedman, 25th ed)

Also Known As:

Networked: 16 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Neoplasms (Cancer)
2.	Myxoma (Myxomas)
3.	Central Nervous System Cysts (Suprasellar Cyst)
4.	Adrenocortical Adenoma (Disease, Conn's)
5.	Thyroid Neoplasms (Thyroid Cancer)

Experts

1.	Boedeker, Nancy C: 1 article (09/2015)
2.	McNeill, Conor J: 1 article (09/2015)
3.	Hope, Katharine L: 1 article (09/2015)
4.	Sander, Samantha J: 1 article (09/2015)
5.	Roberts, John F: 1 article (09/2015)
6.	Murray, Suzan Z: 1 article (09/2015)
7.	Löhr, C V: 1 article (07/2013)
8.	Caswell, J L: 1 article (03/2010)
9.	Wood, G A: 1 article (03/2010)
10.	Hayes, G: 1 article (03/2010)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Myxosarcoma:

1.	Hyaluronic Acid (Hyaluronan)IBA 11/27/1965 - "Properties of hyaluronic acid from a human myxosarcoma." 01/01/1965 - "[HYALURONIC ACID OF HUMAN MYXOSARCOMA. " 01/01/1965 - "[HYALURONIC ACID OF HUMAN MYXOSARCOMA. "
2.	DNA Polymerase I (Klenow Fragment)IBA 01/01/1989 - "1. DNA polymerase alpha isolated from Norman murine myxosarcoma exhibited two isozyme forms, one with low specific activity and low DNA binding affinity (A1), and one with high specific activity and high DNA binding affinity (A2). " 01/01/1989 - "1. DNA polymerase alpha was isolated from Norman Murine Myxosarcoma cells using ion exchange, immunoaffinity, and DNA affinity chromatography, showing two distinct enzyme forms designated A1 and A2. "
3.	DNA (Deoxyribonucleic Acid)IBA 01/01/1989 - "1. DNA polymerase alpha isolated from Norman murine myxosarcoma exhibited two isozyme forms, one with low specific activity and low DNA binding affinity (A1), and one with high specific activity and high DNA binding affinity (A2). " 01/01/1989 - "1. DNA polymerase alpha was isolated from Norman Murine Myxosarcoma cells using ion exchange, immunoaffinity, and DNA affinity chromatography, showing two distinct enzyme forms designated A1 and A2. "
4.	Proliferating Cell Nuclear Antigen (PCNA)IBA 03/01/2002 - "Overexpression of proliferating cell nuclear antigen and low expression of nm23 in myxosarcoma are consistent with the high rate of recurrence and metastasis of this tumor. "
5.	Oncogene Proteins (Oncogene Protein)IBA 03/01/2002 - "The 5 cases of myxosarcoma and 18 randomly selected cases of myxoma were evaluated for proliferative activity, metastatic potential, and oncogene products by immunohistochemistry. "
6.	GossypolIBA 06/01/1987 - "Cytogenetic analysis of gossypol acetate-induced murine myxosarcoma demonstrated a stemline of 78 chromosomes and the presence of three marker (M) chromosomes produced by robertsonian translocation. " 06/01/1987 - "Cytogenetic analysis of a gossypol-induced murine myxosarcoma."
7.	GlycosaminoglycansIBA 06/01/2009 - "The neoplastic cells stained positive for mucopolysaccharides with Alcian blue, resulting in a final diagnosis of low-grade (grade 1) myxosarcoma. "
8.	Amyloid (Amyloid Fibrils)IBA 07/01/2013 - "Single cases of previously unreported caprine tumors included amyloid-producing odontogenic tumor, myxosarcoma, sebaceous carcinoma, apocrine sweat gland adenoma, and thyroid carcinoma. "
9.	Alcian BlueIBA 06/01/2009 - "The neoplastic cells stained positive for mucopolysaccharides with Alcian blue, resulting in a final diagnosis of low-grade (grade 1) myxosarcoma. "
10.	Adrenocorticotropic Hormone (ACTH)FDA Link 03/01/2010 - "The pathological evaluation revealed a left atrial ossifying myxosarcoma, bilateral adrenocortical adenomas, multifocal pituitary hyperplasia with expression of adrenocorticotrophic hormone, and multiple pituitary Rathke's cleft cysts. "

Therapies and Procedures

1.	Thoracotomy 12/01/1981 - "Thoracotomy and biopsy revealed an intrapericardial tumor, histologically myxosarcoma. "
2.	Radiotherapy 12/01/1979 - "Myxosarcoma, a variant of fibrosarcoma, and Ewing's sarcoma of the jaw, are very rare conditions, and since these lesions are usually very extensive radiotherapy is the treatment of choice."
3.	Palliative Care (Palliative Medicine) 05/01/2008 - "Myxomas and myxosarcomas are known to be infiltrative and not readily amenable to surgical removal but their clinical course seems to be slow, with a reasonable survival time with palliative treatment. "
4.	Euthanasia (Mercy Killing) 12/01/1986 - "The dog subsequently developed metastatic cutaneous myxosarcoma and euthanasia was requested by the owners."
5.	Drug Therapy (Chemotherapy) 09/01/2015 - "To our knowledge, this is the first report of a myxosarcoma in a bustard species and the first report of successful clinical application of metronomic chemotherapy in an avian species. " 09/01/2015 - "Metronomic Chemotherapy for Myxosarcoma Treatment in a Kori Bustard (Ardeotis kori)."