Myoglobinuria

11/01/2014 - "The diagnosis is confirmed by myoglobinuria, and an elevated serum Creatinine Phosphokinase (CPK) level, usually 10 times the normal range. "
11/01/1995 - "Characteristic laboratory features include elevated serum creatinine phosphokinase (CPK) (in excess of 90,000 IU/L) and myoglobinuria. "
02/16/1991 - "At the time of admission there were increased plasma creatinine level and phosphokinase activity, with myoglobinuria and increased transaminase activity. "
12/01/2004 - "The sequential addition of admission laboratory values for serum creatinine > or =1.5 mg/dL (positive predictive value [PPV] = 33%), base deficit < or = -4 (PPV = 52%), serum CK level > or =5,000 U/L (PPV = 80%), and myoglobinuria increases the ability to predict which patients will develop dialysis-requiring acute renal failure after an episode of rhabdomyolysis. "
06/01/1993 - "The finding of focal ischemic changes in the pelvic area of a patient with increasing serum creatinine phosphokinase activity, leukocytosis, myoglobinuria and paraplegia following infected aortic graft removal signals a grave and fatal prognosis."

07/01/1993 - "From a history of use of succinylcholine as a muscle relaxant during operation, myoglobinuria appears to be secondary to muscle damage caused by succinylcholine."
07/01/1993 - "Myoglobinuria following the use of succinylcholine."
11/01/1968 - "Myoglobinuria following the use of suxamethonium chloride. "
05/01/1968 - "Myoglobinuria following anaesthesia including suxamethonium."
05/01/1983 - "Following an uneventful anaesthetic, which included succinylcholine, myoglobinuria developed and led to renal failure which fortunately reversed with conservative treatment. "

10/01/1990 - "Certain clinical features were found to be of more value as predictors than others; these included a high creative kinase and myoglobinuria. "
05/01/2015 - "Compared with DMD, BMD is clinically more heterogeneous, with initial presentation in the teenage years and loss of ambulation beyond the age of 16 and a wide spectrum of clinical presentations, ranging from only myalgias and muscle cramps to exercise intolerance and myoglobinuria, asymptomatic elevation of serum creatin-kinase, or mild limb-girdle weakness and quadriceps myopathy. "
03/01/1999 - "Laboratory tests revealed marked elevation of creatinine kinase(CK) levels and myoglobinuria. "
06/06/1992 - "These diseases are usually recognized when exercise-induced myalgias, myoglobinuria and raised creatinine kinase (CK) levels are present. "
05/01/2008 - "Myoglobinuria cleared with hydration and creatinine kinase levels returned to normal; however, the patient ultimately developed gangrene of both lower extremities. "

04/01/1989 - "The elevated CK levels initially decreased, serum potassium levels were found to be within normal limits, and myoglobinuria was not detected during the further course. "
01/01/1989 - "The poor clinical features contrasted with the severe biological disturbances: 1 mmol.l-1 serum potassium, pH 7.26, 19 mmHg PaCO2, 8 mmol.l-1 bicarbonate, myoglobinaemia and myoglobinuria. "
10/22/1966 - "[Potassium depletion and myoglobinuria caused by the use of licorice]."
01/31/1987 - "Symptoms linked with serum Potassium depletion: asthenia, paralysis (due to Potassium deficiency), myopathy with myoglobinuria. "
07/01/1976 - "Electrocardiographic changes, venous and arterial plasma potassium and calcium levels, CPK changes (12 patients) and appearance of myoglobinuria (35 patients) were followed. "

08/14/1992 - "The cause of the symptoms was rhabdomyolysis with an increased creatinine activity of 1000 U/l and marked myoglobinuria (1600 micrograms/l), as well as renal failure with normal uric acid and a creatinine clearance of 3 ml/min per 1.73 m2. "
08/01/2008 - "Laboratory examinations showed acute renal failure due to myoglobinuria and revealed alanine transaminase 428 U/l, aspartate transaminase 1,400 U/l, blood urea nitrogen 119 mg/dl, creatinin 3.6 mg/dl, uric acid 13 mg/dl, and serum creatinine kinase (CK) 33,766 U/l. "

10/01/1994 - "We recommend performing a medical history, physical examination, SMA-7, calcium, CPK if there is possible myoglobinuria, alcohol and drug screens, computed tomography scan, and lumbar puncture as part of the medical clearance of these patients."
07/01/1976 - "Electrocardiographic changes, venous and arterial plasma potassium and calcium levels, CPK changes (12 patients) and appearance of myoglobinuria (35 patients) were followed. "

07/01/1976 - "Pretreatment with a small dose of d-tubocurarine is effective in preventing or decreasing fasciculations, plasma potassium and CPK changes and myoglobinuria described after the intravenous administration of succinylcholine. "

01/01/2012 - "Despite rapid clearance of the parasitemia with intravenous artesunate and aggressive hydration maintaining good urine output, his myoglobinuria and acidosis worsened, progressing to uremia requiring renal replacement therapy. "

08/01/2014 - "Laboratory studies were notable for myoglobinuria and markedly elevated plasma creatine kinase (CK) level of 7315 U/L. "
01/01/2012 - "To address this, a six-minute ambulation assay, serum creatine kinase, and myoglobinuria were investigated for the mdx mouse, a dystrophinopathy mouse model commonly used in pre-clinical studies. "
12/01/2014 - "Laboratory findings revealed highly increased creatine phosphokinase and myoglobinuria. "
11/01/2014 - "Patients with myoglobinuria were more likely to be symptomatic (Fisher's exact test, p = 0.006), whereas neither myoglobinuria (Mann-Whitney test, p > 0.10) nor symptoms (Mann-Whitney test, p = 0.64) were related to the magnitude of the creatine kinase (CK) elevation. "
01/01/2014 - "Secondary outcome measures included metabolic changes (such as reduced plasma creatine kinase and a reduction in the frequency of myoglobinuria), subjective measures (including quality of life scores and indices of disability) and serious adverse events.Data"

10/21/2013 - "In this study, we report a case with adult myopathic form of CPT II deficiency presenting recurrent exercise-induced myoglobinuria. "
03/15/2008 - "Carnitine palmitoyltransferase II (CPT II) deficiency is the most common inherited disorder of lipid metabolism characterized in its adult form by attacks of myalgia and myoglobinuria. "
08/01/2005 - "Carnitine palmitoyltransferase II (CPT II) deficiency is an autosomal recessive disorder which presents with recurrent myoglobinuria. "
02/25/2005 - "CPT II deficiency should be suspected in patients with persistent exertional myalgia who have one or more episodes of myoglobinuria. "
02/25/2005 - "Recurrent myoglobinuria due to carnitine palmitoyltransferase II deficiency: clinical, biochemical, and genetic features of adult-onset cases."

10/01/1993 - "Myoglobinuria was documented in all five patients and cleared within 24 hours of physiologic amputation in four patients. "
07/01/2005 - "Patients with gross myoglobinuria are at higher risk of requiring fasciotomy and/or amputation."
07/01/2005 - "Amputation was predicted by a logistic model incorporating myoglobinuria, undergoing a previous fasciotomy, and age, with an overall accuracy of 73.3%. "
10/01/1993 - "Physiologic amputation prevents myoglobinuria from lower extremity myonecrosis."
10/01/1993 - "Physiologic amputation may be appropriately used in patients with myoglobinuria due to extremity myonecrosis who are deemed too critically ill to survive emergency amputation."

12/01/2008 - "Urgent fasciotomies were performed and the patient underwent urgent renal replacement therapy with continuous hemodialysis for acute renal failure due to myoglobinuria. "
01/01/2012 - "Despite rapid clearance of the parasitemia with intravenous artesunate and aggressive hydration maintaining good urine output, his myoglobinuria and acidosis worsened, progressing to uremia requiring renal replacement therapy. "

03/01/1982 - "In a 11 1/2 year-old boy, acute myolysis with myoglobinuria followed anesthesia and had a favourable outcome. "
03/01/1982 - "[Myoglobinuria following anesthesia (author's transl)]."
11/01/1968 - "[Episode of paroxysmal myoglobinuria in anesthesia]."
02/01/1988 - "The neuroleptic malignant syndrome (NMS) is similar to anesthesia-induced malignant hyperthermia (MH) in three major clinical features: hyperthermia, muscular rigidity, and myoglobinuria. "
04/02/1979 - "[Myoglobinuria after halothane-suxamethone anesthesia]."

07/01/2013 - "The disease went unrecognized despite previous symptoms (myalgia, exercise intolerance and single myoglobinuria episode) until an episode of rhabdomyolisis complicated with oliguric acute kidney injury requiring hemodialysis. "
02/01/2006 - "Hemodialysis was begun 3 days after the onset of myoglobinuria when acute renal failure was noted, despite aggressive fluid supplementation and alkaline diuresis. "
12/01/2008 - "Urgent fasciotomies were performed and the patient underwent urgent renal replacement therapy with continuous hemodialysis for acute renal failure due to myoglobinuria. "
06/01/1989 - "One patient died during hemodialysis for renal failure resulting from prolonged shock and myoglobinuria. "
06/01/1997 - "Another patient with high serum creatine kinase levels and myoglobinuria developed renal failure requiring hemodialysis. "

08/01/2014 - "Present case describes an interesting report of myoglobinuria in a patient with post transplant diabetic nephropathy mimicking acute graft rejection. "
05/01/2004 - "After a few hours the patient showed myoglobinuria, rhabdomyolysis and a fast-deteriorating graft function. "
08/01/2014 - "Myoglobinuria masquerading as acute rejection in a renal allograft recipient with recurrent post transplant diabetic nephropathy."
03/01/2006 - "An evolving list of indications for subatmospheric pressure therapy is discussed including its use in chronic wounds, traumatic wounds and orthopedic salvage, infected sternal wounds, management of the open abdomen, enterocutaneous fistulae, burn wounds, skin grafts and dermal substitutes, as well as systemic disease processes, such as myoglobinuria. "
06/01/1993 - "The finding of focal ischemic changes in the pelvic area of a patient with increasing serum creatinine phosphokinase activity, leukocytosis, myoglobinuria and paraplegia following infected aortic graft removal signals a grave and fatal prognosis."