Miliaria (Prickly Heat)

A syndrome of cutaneous changes associated with sweat retention and extravasation of sweat at different levels in the skin. Miliaria rubra, or prickly heat, results from apocrine duct obstruction. The sweat then seeps into the epidermis, producing pruritic erythematous papulovesicles. (From Dorland, 27th ed)

Also Known As:

Networked: 30 relevant articles (1 outcomes, 3 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Skin Diseases
2.	Scabies (Sarcoptic Mange)
3.	Seborrheic Dermatitis
4.	Impetigo
5.	Furunculosis (Boils)

Experts

1.	Davis, Mark D P: 1 article (12/2015)
2.	Andersen, Louise K: 1 article (12/2015)
3.	Cusack, Carrie Ann: 1 article (04/2013)
4.	Allen, Herbert B: 1 article (04/2013)
5.	Haque, Maryam S: 1 article (04/2013)
6.	Pritchett, Ellen: 1 article (04/2013)
7.	Hailu, Tesfu: 1 article (04/2013)
8.	Keskindemirci, Gonca: 1 article (01/2012)
9.	Onal, Zerrin: 1 article (01/2012)
10.	Adal, Erdal: 1 article (01/2012)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Miliaria:

1.	Papular urticariaIBA 04/01/2004 - "Insect bite reactions (papular urticaria) (5.27%) and miliaria (4.1%) were attributed to the tropical weather conditions in this coastal area. " 01/01/2010 - "The top six skin diseases in our study were impetigo, miliaria, scabies, furunculosis, seborrheic dermatitis and papular urticaria. " 12/01/2015 - "El Niño has been associated with increases in the occurrence of actinic keratosis, tinea, pityriasis versicolor, miliaria, folliculitis, rosacea, dermatitis by Paederus irritans and Paederus sabaeus, and certain vector-borne and waterborne diseases, such as dengue fever, leishmaniasis, Chagas' disease, Barmah Forest virus, and leptospirosis, and with decreases in the occurrence of dermatitis, scabies, psoriasis, and papular urticaria. "
2.	Periodic AcidIBA 04/01/2013 - "The study also confirmed the findings by earlier investigators about the blockage of sweat ducts in miliaria, showing eosinophilic material in the ducts that was positive for periodic acid-Schiff. " 11/01/1995 - "An accumulation of periodic acid-Schiff (PAS)-positive material has been described as blocking the sweat duct in miliaria. "
3.	CoagulaseIBA 11/01/1995 - "Previous studies have indicated that cutaneous bacteria, particularly coagulase-negative staphylococci, play a role in the pathogenesis of miliaria. " 11/01/1995 - "We evaluated the relative ability of various species of coagulase-negative staphylococci to induce miliaria with particular reference to the potential role of EPS. "
4.	Isotretinoin (Accutane)FDA LinkGeneric 10/01/1986 - "To our knowledge, the association of miliaria crystallina with isotretinoin therapy has not been previously reported." 10/01/1986 - "Miliaria crystallina occurring in a patient treated with isotretinoin." 10/01/1986 - "A case of miliaria crystallina occurring with isotretinoin therapy in a patient with lamellar ichthyosis is described. " 11/01/1996 - "We describe a patient with miliaria profunda who responded to therapy with anhydrous lanolin and isotretinoin. " 05/01/2005 - "In addition to known predisposing factors such as heat, humidity, and fever, a few drugs (eg, isotretinoin and bethanechol) can also precipitate miliaria. "
5.	Bethanechol (Duvoid)FDA LinkGeneric 05/01/1967 - "Iatrogenic miliaria crystallina due to bethanechol." 05/01/2005 - "In addition to known predisposing factors such as heat, humidity, and fever, a few drugs (eg, isotretinoin and bethanechol) can also precipitate miliaria. "
6.	NeomycinFDA LinkGeneric 05/01/1955 - "The treatment of miliaria rubra with neomycin lotion." 06/01/1956 - "Neomycin lotion in the treatment of miliaria rubra (prickly heat)."
7.	Ascorbic Acid (Vitamin C)FDA LinkGeneric 07/20/1968 - "Ascorbic acid for prickly heat." 06/22/1968 - "Ascorbic acid for prickly heat."
8.	Cytochromes b (Cytochrome b)IBA 06/01/2008 - "The phylogeny of the avian genus Emberiza and the monotypic genera Latoucheornis, Melophus and Miliaria (collectively the Old World Emberizini), as well as representatives for the New World Emberizini, the circumpolar genera Calcarius and Plectrophenax and the four other generally recognized tribes in the subfamily Emberizinae was estimated based on the mitochondrial cytochrome b gene and introns 6-7 of the nuclear ornithine decarboxylase (ODC) gene. "
9.	Polyethylene (Polythene)IBA 09/01/1980 - "Miliaria rubra (heat rash) was then induced on the experimental subjects by wrapping them for 3 days in polyethylene plastic. "
10.	Vitamin A (Retinol)FDA LinkGeneric 10/01/1951 - "Generalized miliaria rubra associated with abnormal vitamin A metabolism."

Therapies and Procedures

1.	Aftercare (After-Treatment) 05/01/2005 - "We report an autosomal recessive PHA-I in a 4-year-old girl, with cutaneous lesions mimicking miliaria rubra, that improved after treatment with astringent solutions and avoidance of profuse sweating."
2.	Intensive Care (Surgical Intensive Care) 01/01/2004 - "We present two febrile intensive care patients in whom enhanced alpha-adrenergic stimulation of sweat gland myoepithelia may have led to miliaria crystallina." 01/01/2004 - "Miliaria crystallina in an intensive care setting."
3.	Radiotherapy 06/01/1988 - "Keratotic miliaria precipitated by radiotherapy."
4.	Drug Therapy (Chemotherapy) 07/01/2011 - "Miliaria-rash after neutropenic fever and induction chemotherapy for acute myelogenous leukemia."