Methylprednisolone

10/01/1994 - "The National Acute Spinal Cord Injury Study II concluded in 1990 that high-dose methylprednisolone (MP) improved neurologic recovery after acute spinal cord injury (ASCI). "
11/01/1985 - "A multi-center double-blind randomized clinical trial was conducted by the National Acute Spinal Cord Injury Study Group to examine the efficacy of high-dose methylprednisolone (1000-mg bolus and 1000 mg daily thereafter for 10 days) compared with that of a standard dose (100-mg bolus and 100 mg daily for 10 days). "
01/06/1984 - "A multicenter double-blind randomized trial was conducted to examine the efficacy of a high dose of methylprednisolone (1,000-mg bolus and daily thereafter for ten days) compared with a standard dose (100-mg bolus and daily thereafter for ten days) in 330 patients with acute spinal cord injury. "
01/01/2000 - "High-dose intravenously administered methylprednisolone has been shown to improve outcome after spinal cord injury. "
07/01/1999 - "Clinically, high-dose treatment with the glucocorticosteroid, methylprednisolone (MP), within 8 h after spinal cord injury, has been shown to improve neurological recovery. "

03/01/2007 - "In the case of lumbar radicular pain, ESI with low dose (40 mg) methylprednisolone is as effective as high dose (80 mg) with comparable results and less adverse profile."
06/05/1997 - "After six weeks, the only significant difference was the improvement in leg pain, which was greater in the methylprednisolone group (P=0.03). "
03/01/1987 - "In both groups a statistically significant improvement of pain on mobilisation and pain index was noted, but the number of clinical remissions was significantly higher in the methylprednisolone group. "
09/01/2015 - "Methylprednisolone was not shown to be effective for reducing pain. "
01/01/2002 - "These results suggest that periarticular injection of methylprednisolone may be effective in the treatment of pain in the region of the SIJ in non-spondylarthropathic patients."

03/01/1999 - "This study was done to determine the efficacy of oral high dose methylprednisolone (HDMP) therapy in the treatment of childhood nephrotic syndrome (NS). "
01/01/2015 - "Methylprednisolone therapy is effective in KD associated with nephrotic syndrome, and long-term administration of methylprednisolone at maintenance dose may be a way to prevent relapses of KD."
01/01/2015 - "Twenty-seven days after the three methylprednisolone pulses, her acute renal dysfunction was improved, but the nephrotic syndrome was not improved. "
03/01/2009 - "The steroid resistance of nephrotic syndrome is defined by the absence of remission after a full dose of oral corticosteroid therapy for 1 month followed by 3 pulses of intravenous methylprednisolone. "
11/01/2004 - "Efficacy of methylprednisolone pulse therapy in steroid-resistant nephrotic syndrome."

06/01/1995 - "It is important for medical-surgical nurses to understand the pathophysiology of multiple sclerosis, as well as recent evidence suggesting that intravenous methylprednisolone treatment may be effective for treating exacerbations of the disease. "
02/01/1988 - "This study confirms that high dose methylprednisolone is a safe therapeutic option in multiple sclerosis."
06/01/2015 - "High-dose, intravenous methylprednisolone (MP) is the only recommended first-line treatment for multiple sclerosis relapses. "
11/01/2014 - "Short-term, high-dose intravenous methylprednisolone therapy (IVMP), which is called steroid pulse therapy, is widely used as the standard treatment for acute exacerbations of multiple sclerosis (MS), and has been shown to improve neurological symptoms. "
03/01/2002 - "To investigate the efficacy of two different high doses of intravenous methylprednisolone (IVMP) during Multiple Sclerosis (MS) relapses. "

09/01/2012 - "Within 72 hours of intravenous methylprednisolone treatment, the orbital inflammation dramatically improved. "
04/01/2002 - "Since sequential MRI studies showed prompt reduction of the cord swelling, the high-dose methylprednisolone therapy employed seemed to have been effective for improvement of inflammation. "
01/01/2007 - "High-dose intravenous methylprednisolone pulse therapy may be beneficial in the prompt control of severe ocular inflammation and in preventing visual loss."
05/01/1993 - "Bronchial lavages with methylprednisolone were effective in some patients with severe airway inflammation. "
06/01/2013 - "Methylprednisolone in neonatal cardiac surgery: reduced inflammation without improved clinical outcome."