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Methylergonovine (Methergine)

Subscribe to New Research on Methylergonovine

A homolog of ERGONOVINE containing one more CH2 group. (Merck Index, 11th ed)

Also Known As:

Methergine; Methylergometrine; Methergin; Methylergometrine Maleate; Methylergonovine Maleate; Méthergin; Novartis Brand of Methylergonovine Maleate; Methylergobasin; Methylergometrin; Ergoline-8-carboxamide, 9,10-didehydro-N-(1-(hydroxymethyl)propyl)-6-methyl-, (8beta(S))-

Networked: 145 relevant articles (10 outcomes, 21 trials/studies)

Relationship Network

Drug Context: Research Results

Heterocyclic Compounds: 60
- Alkaloids: 1065
  - Ergot Alkaloids: 156
    - Ergolines: 88
      - Ergonovine: 688
        Methylergonovine: 145
- Heterocyclic Compounds with 4 or More Rings
  - Ergolines: 88
    - Ergonovine: 688
      - Methylergonovine: 145

Experts

1.	Bateman, Brian T: 3 articles (05/2015 - 11/2013)
2.	Aboukhoudir, F: 2 articles (11/2015 - 11/2012)
3.	Pansieri, M: 2 articles (11/2015 - 11/2012)
4.	Rekik, S: 2 articles (11/2015 - 11/2012)
5.	Aboukhoudir, I: 2 articles (11/2015 - 11/2012)
6.	Butwick, Alexander J: 2 articles (05/2015 - 12/2014)
7.	Liu, Jun: 2 articles (12/2014 - 11/2013)
8.	Huybrechts, Krista F: 2 articles (12/2014 - 11/2013)
9.	Hung, Ming-Jui: 2 articles (08/2011 - 05/2008)
10.	Cheng, Chi-Wen: 2 articles (08/2011 - 05/2008)

Related Diseases

1.	Postpartum Hemorrhage 05/01/2011 - "Methylergonovine (MEV) is a semi-synthetic ergot alkaloid used in the prevention and control of postpartum hemorrhage. " 10/25/1957 - "[Directed methergine administration in prevention of postpartum hemorrhage]." 01/01/1952 - "[Methergine in prophylaxis of postpartum hemorrhage]." 06/15/2015 - "Cesarean Delivery in a Parturient with Left Ventricular Noncompaction Complicated by Acute Pulmonary Hypertension After Methylergonovine Administration for Postpartum Hemorrhage." 03/01/2008 - "To assess the efficacy of rectal misoprostol as second-line therapy in the management of primary postpartum hemorrhage (PPH) as compared to methylergonovine maleate. "
2.	Endometritis 01/01/2000 - "The women receiving methergine had a significant reduction in the rate of postoperative endometritis (10% vs. 36%, P < 0.005). " 01/01/2000 - "Methergine increases constriction of uterine musculature which may facilitate sloughing of endometrial debris, close uterine vessels, and prevent post-cesarean endometritis. " 01/01/2000 - "The objective of this study was to evaluate the efficacy of methergine in preventing endometritis in patients undergoing non-elective cesarean section delivery. " 01/01/2000 - "The use of methergine postpartum in women undergoing non-elective cesarean sections significantly reduces the incidence of postoperative endometritis and blood loss." 01/01/2000 - "Use of methergine for the prevention of postoperative endometritis in non-elective cesarean section patients."
3.	Hemorrhage 12/01/2008 - "We believe this is the first reported case of pulmonary alveolar hemorrhage caused by methylergometrin, confirmed by bronchoscopy." 12/01/2008 - "[A case of pulmonary alveolar hemorrhage caused by methylergometrine]." 01/01/2003 - "Methylergometrine is often used in the management of the third stage of labor and for treatment of prevention of puerperal hemorrhage. " 11/01/2001 - "[Acute anterior wall infarct in a 31-year-old patient after administration of methylergometrin for peripartal vaginal hemorrhage]." 05/01/1994 - "We discuss the role of methylergometrine, used for avoid the bleeding postpartum, in its etiopathology and its specific therapy."
4.	Migraine Disorders (Migraine) 01/01/2009 - "Although limited by the non-controlled design of the study, our data suggest that intravenous methylergonovine can be an effective and safe drug in the management of severe migraine attacks in the emergency room." 01/01/2009 - "Efficacy and tolerability of intravenous methylergonovine in migraine female patients attending the emergency department: a pilot open-label study." 03/01/2011 - "She had a history of migraines and received methylergonovine at delivery. " 01/01/2009 - "One hundred and twenty five female patients with migraine attending the emergency department received 0.15 mg of methylergonovine intravenously. " 01/01/2009 - "The purpose of the present study was to assess the potential therapeutic effectiveness of methylergonovine in the emergency treatment of severe migraine. "
5.	Headache (Headaches) 07/01/1993 - "It is concluded that methylergonovine maleate is effective in the initial control of drug induced refractory headache. " 07/01/1997 - "A review of methylergonovine's pharmacokinetic, molecular, and tolerability profile clarifies its mechanisms and clinical role in headache management." 02/01/2004 - "The history disclosed that obstetricians had used methylergometrine maleate for uterine contraction after delivery and then sumatriptan for her throbbing headache. " 07/01/1993 - "This study investigated the efficacy of methylergonovine maleate (Methergine) in the treatment of drug induced refractory headache (DIRH). " 07/01/1993 - "The use of methylergonovine (Methergine) in the initial control of drug induced refractory headache."

Related Drugs and Biologics

1.	Methylergonovine (Methergine)
2.	Oxytocin (Pitocin)
3.	Misoprostol (Cytotec)
4.	Analgesics (Analgesic Drugs)
5.	Nitroglycerin (Dynamite)
6.	Ergonovine (Ergometrine)
7.	Dinoprost
8.	Methysergide (Sansert)
9.	carboprost tromethamine
10.	Sodium Chloride (Saline Solution)

Related Therapies and Procedures

1.	Cesarean Section (Caesarean Section)
2.	Intravenous Infusions
3.	Emergency Treatment
4.	Intravenous Injections
5.	Heart Transplantation (Grafting, Heart)