Methylcellulose (BFL)

Methylester of cellulose. Methylcellulose is used as an emulsifying and suspending agent in cosmetics, pharmaceutics and the chemical industry. It is used therapeutically as a bulk laxative.

Also Known As:

Networked: 735 relevant articles (40 outcomes, 79 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Shoichet, Molly S: 8 articles (01/2019 - 09/2009)
2.	Ohtani, Yoshio: 7 articles (12/2008 - 05/2003)
3.	Yoshizawa, Yasuyuki: 7 articles (12/2008 - 05/2003)
4.	Millon, Laurence: 6 articles (07/2022 - 01/2014)
5.	Reboux, Gabriel: 6 articles (07/2022 - 01/2014)
6.	Rouzet, Adeline: 6 articles (07/2022 - 01/2014)
7.	Inase, Naohiko: 6 articles (12/2008 - 05/2003)
8.	Cammalleri, Maurizio: 4 articles (11/2023 - 03/2020)
9.	Dal Monte, Massimo: 4 articles (11/2023 - 03/2020)
10.	Rusciano, Dario: 4 articles (01/2023 - 03/2020)

Related Diseases

1.	Body Weight (Weight, Body) 10/01/2008 - "In conclusion, heavy housework, walking (faster pace), sports/recreational activities, and overall total participation in low-impact PA were beneficial for bone and for achieving more favorable body weight and fat but were not associated with BFL. " 01/01/2012 - "In the sub-chronic oral toxicity study, the animals were orally administered with CS extract (1000, 2000 and 3000mg/kg body weight) daily for 28 days whereas; vehicle control group received 0.5 % carboxy methyl cellulose. " 02/01/1999 - "2-YEAR STUDIES: AZT Groups of 95 male and 95 female mice received AZT in 0.5% methylcellulose by gavage at daily doses of 0, 30, 60, or 120 mg/kg body weight, administered as two equal doses at least 6 hours apart, 5 days per week for 105 weeks. " 01/01/2021 - "Group A was run as control and given single oral dose of 1% methyl-cellulose (10mg/100gm body weight of rat). " 10/01/2018 - "Group A (control) was provided with single oral dose of 10 mg/100 gm body weight of 1% methyl cellulose. "
2.	Neoplasms (Cancer) 06/05/2022 - "Mechanistic studies show that 12 inhibited BFL-1/PUMA interaction in cell lysate and is effective in cancer cells that harboring high expression level of BFL-1. " 01/01/2023 - "While increasing evidence suggests BFL-1/A1 is a resistance factor for diverse chemotherapeutic agents and BH3-mimetic drugs in haematological malignancies, few studies have explored the role of BCL-W in the development, expansion, and therapeutic responses of cancer. " 12/01/2020 - "These studies lay a foundation for developing more advanced dual Mcl-1/Bfl-1 inhibitors that have potential to provide greater single agent efficacy and broader coverage to combat resistance in several types of cancer than selective Mcl-1 inhibitors alone." 10/01/2020 - "Ultimately, the combination significantly decreased colony formation in a semisolid methylcellulose medium and tumor mass in xenografted zebrafish compared to each compound alone. " 05/01/2019 - "The treatment with 100 μg/μL of either native or recombinant BfL (nBfL or rBfL) significantly reduced the proliferation of both cancer cell lines (p < 0.01). "
3.	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 12/01/2004 - "MOZ-TIF2-transduced progenitors could be serially replated in methylcellulose cultures and continuously propagated in liquid culture, and resulted in an acute myeloid leukemia in vivo that could be serially transplanted. " 05/01/1993 - "Leukemic blast progenitors in acute myeloid leukemia (AML) undergo terminal divisions giving rise to colonies in methylcellulose. " 12/01/1990 - "In order to evaluate whether BCM might contain an activity inhibiting the growth of normal marrow progenitors, BCM from 13 consecutive patients with ANLL were tested on normal bone marrow in methylcellulose assays. " 12/01/1989 - "Mononuclear normal bone marrow cells, blasts from patients with ANLL, and HL-60 cells were incubated at room temperature (control) and at 42 degrees-44 degrees C for 0-120 min prior to assay in methylcellulose. " 01/01/1988 - "For monitoring the effect of chemotherapy in acute myeloid leukemia (AML), we attempt to detect minimal numbers of AML clonogenic cells (CFU-L) during remission using light density gradients combined with PHA-LCM methyl cellulose assay. "
4.	Wounds and Injuries (Trauma) 05/01/2016 - "The goal of the present study was to evaluate the effects of hydroalcoholic extract-based carboxy methyl cellulose (CMC) gel of Punica granatum peel (PCMC) and CMC on healing of full-thickness skin wounds. " 01/01/1990 - "A time course study was performed of full thickness 6 mm punch wounds placed on the backs of anesthetized pigs and treated once with either 3% methylcellulose or rhTGF-beta 1 in 3% methylcellulose or left untreated. " 02/01/2024 - "A novel designed nanofibrous mat based on hydroxypropyl methyl cellulose incorporating mango peel extract for potential use in wound care system." 05/02/2017 - "It also healed wounds more quickly, with the average expected healed weeks 34.4 in the SBG gel group, compared with 24.7 methylcellulose dressing group. " 03/01/2013 - "The L exercises load the proximal regions of the BFl and AM. These findings may have relevance when designing protocols for prevention and rehabilitation of hamstring injuries."
5.	Infections 05/01/1992 - "In this study, normal bone marrow mononuclear cells were infected in vitro with HHV-6, and a methylcellulose-based colony formation assay was used to evaluate the impact of the infection on marrow cell differentiation and proliferation. " 02/01/1989 - "This combination of marrow cell infection by coculture and colony-forming unit (CFU) assessment by methylcellulose assay provides a reliable in vitro technique for studies of mechanisms involved in retrovirus-induced marrow aplasias." 01/01/2022 - "Multi-lineage colony formation in methylcellulose assays and repetitive replating of transduced cells provided functional proof of susceptibility of primitive HSPCs to HIV-1 infection. " 04/01/2011 - "First, we have confirmed that upon infection virulent strain H37Rv retain Bfl-1/A1 for longer period and impose autophagosome maturation block within infected cells as evident from confocal microscopy. " 04/01/2011 - "Present work was undertaken to deduce the significance of differential expression of Bfl-1/A1 in the outcome of mycobacterial infection. "

Related Drugs and Biologics

1.	Hyaluronic Acid (Hyaluronan)
2.	Hydrogels
3.	Methylcellulose (BFL)
4.	Psyllium (Metamucil)
5.	Sodium
6.	Carboxymethylcellulose Sodium (Polycell)
7.	Polymers
8.	Conditioned Culture Media
9.	Chitosan
10.	Tablets

Related Therapies and Procedures

1.	Therapeutics
2.	Injections
3.	Drug Therapy (Chemotherapy)
4.	Induced Labor
5.	Aftercare (After-Treatment)