Metalloproteins

01/01/2007 - "For an improved diagnosis and therapy of neurodegenerative diseases, new methodologies have to be developed that enable a well-defined differentiation between properly folded and inactive metalloproteins in clinical samples. "
10/01/2008 - "In this review, we highlight how biological XAS is being used in concert with crystallography, spectroscopy and computational chemistry to study metalloproteins in crystals, and report recent applications on relatively rare trace elements utilised by living organisms and metals involved in neurodegenerative diseases."
03/01/2000 - "These included the molecular and cellular basis of copper transport, molecular advances in Menkes and Wilson's diseases, the involvement of copper in neurodegenerative diseases, the structure and function of copper metalloproteins."
01/01/2010 - "Especially, in brain research metalloproteins are in the focus of targeted therapy approaches of neurodegenerative diseases such as Alzheimer's and Parkinson's disease, or stroke, or tumor growth. "

12/01/2007 - "The aim of this study was to investigate the relationship between metalloproteins distributions and cancer development in human liver tissues. "
03/01/2013 - "In addition, the anti-tumor active CP remained in plasma for more than 50 min. Furthermore, NAC (but not CP) adversely affected the integrity of Fe and Zn plasma metalloproteins in a dose and a time dependent manner. "
01/01/1975 - "[Level of certain metalloproteins of blood in development and treatment of neoplasms of the uveal tract]."
12/01/2007 - "Expression of particular metalloproteins has correlation with lymph node metastasis, tumor invasiveness, and overall prognosis in HNSCC."
02/01/2007 - "A number of metalloproteins are important medicinal targets for conditions ranging from pathogenic infections to cancer. "

07/01/2001 - "Cellular response of antioxidant metalloproteins in Cu/Zn SOD transgenic mice exposed to hyperoxia."
07/01/2001 - "In this study, we have used copper- and zinc-containing superoxide dismutase (Cu/Zn SOD) transgenic-overexpressing and gene knockout mice and hyperoxia to investigate the effects of chronic and acute oxidative stress on the expression of these metalloproteins and to identify their influence on copper, zinc, and iron homeostasis. "

05/29/2013 - "This study opens up a new avenue to investigating the rupture mechanism of metal centers in metalloproteins with unprecedented resolution by using single molecule force spectroscopy techniques."

02/01/2007 - "A number of metalloproteins are important medicinal targets for conditions ranging from pathogenic infections to cancer. "
03/01/2001 - "In this review the authors summarize the experimental data on the role of a selected group of metalloproteins, particularly viral (v) and cellular (c) zinc finger proteins (ZFP) and iron containing proteins which are involved in cell proliferation, neovascularization, apoptosis, and viral infection. "
08/10/1978 - "T4D phage infection was found to shut off the synthesis of all bacterial host zinc metalloproteins while allowing the formation of viral-induced zinc proteins. "