Mercaptoethanol (2 Mercaptoethanol)

04/01/2012 - "Studies on BALB/c mice with EC9706 solid tumors demonstrated significantly greater inhibition of tumor growth following treatment with 2-ME nanosuspension than 2-ME solution at the same dosage. "
09/30/2002 - "In vivo, 2-ME caused a slight inhibition of tumor growth, with no tumors cured. "
09/01/2001 - "2-ME administration suppressed tumor growth and improved the efficacy of RIT in comparison to RIT alone. "
01/01/2015 - "Herein, the anti-cancer effects, the results from the clinical trial development programs and the synthetic studies towards 2-ME, are reviewed. "
01/01/2009 - "Our previous studies have shown that 2-ME can suppress growth of pancreatic tumor cells in vitro and in vivo by the induction of apoptosis (Cancer Res 66: 4309-18, 2006). "

03/01/2010 - "Follow-up standard agglutination and 2-mercaptoethanol tests in 175 clinically cured cases of human brucellosis."
05/01/1978 - "The relative efficacy of the card test in the diagnosis of human brucellosis was evaluated by comparison with four other tests: the standard tube agglutination test, centrifugation agglutination test, 2-mercaptoethanol degradation technique, and 2-mercaptoethanol centrifugation agglutination test. "
05/01/1991 - "The serum agglutination test (SAT) and 2-mercaptoethanol (2ME) agglutination were used in studies of the sera of 214 patients in whom brucellosis was suspected. "
08/01/1972 - "[Studies on the usefulness of the mercaptoethanol test for the identification of unspecific brucellosis reactors]."
09/01/2013 - "A case with STA titer ≥ 1:80, 2-mercaptoethanol (2ME) agglutination ≥ 40 and compatible signs and symptoms was considered positive for brucellosis. "

01/01/2013 - "In this study, we investigated the effects of 2-ME on cell viability, proliferation, cell cycle, and apoptosis in human urothelial carcinoma (UC) cell lines. "
03/01/2012 - "In this study, we determined the antitumour activities of 2-ME on the well-differentiated EC9706 esophageal carcinoma cells in vitro. "
01/01/2011 - "In the present study, we investigated the effects of 2-ME on cell proliferation and cell cycle of two human colon carcinoma cell lines, namely HCT116 and SW613-B3. "
03/01/2005 - "In this study, we investigated the antitumoral effects of 2-ME on human cervical carcinoma in severe combined immune deficient (SCID) mice. "
08/01/2001 - "Thus, another objective of this study was to evaluate the relation between cell cycle arrest, ROS formation, and caspase activity levels after 2-Me treatment in gastric carcinoma cells. "

09/30/2002 - "2-ME has already shown actions in pharmacological dosages which led already to a first trial to prove its suitability for treating human breast cancer."
04/01/2000 - "In addition, MCF-7 breast cancer cells were also radiosensitized by 2 microM 2-ME (DER = 2.1). "
01/01/1997 - "In vitro screening has determined that breast cancer cell lines are most sensitive to inhibition by 2-ME. "
04/01/2012 - "So 2-ME microspheres are acceptable for controlled release devices for effective treatment of breast cancer."
05/01/2011 - "By monitoring tumor volume and CD31 immunohistochemical staining in mouse orthotopic breast tumor (MDA-MB-231) model, it was found that the hydrogel containing a relatively low concentration (15 mg/kg) of 2-ME showed the improved antitumor and antiangiogenic activity relative to the original formulation. "

03/01/1978 - "Both procedures successfully related antibody titres to time post-infection, but it was considered that a 2 M 2-ME HI procedure showed the greater promise for field investigations."
07/01/1994 - "The 2-mercaptoethanol test which gave positive results in 63.8% of cases provided additional information characterizing the course of infections process."
04/01/2013 - "Standard agglutination test (SAT) with titers > 1:160 and the 2-mercaptoethanol (2ME) test ≥ 1:80 are suggestive of active infection. "
01/01/2011 - " canis infection using the rapid slide agglutination test (RSAT), the microagglutination test (MAT), and the 2-mercaptoethanol RSAT test (2ME-RSAT). "
11/01/2007 - "The all experimentally infected dogs were positive in ICA, HC and 2-ME RSAT from 5 weeks, 7 weeks, and 3 weeks after infection, respectively. "