Mepivacaine (Carbocaine)
A local anesthetic that is chemically related to BUPIVACAINE but pharmacologically related to LIDOCAINE. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)
Also Known As:
Carbocaine; Scandonest; Carbocaïne; Isocaine; Isogaine; Meaverin; Mecain; Mepihexal; Mepivacain-Injektopas; Mepivacaina Braun; Mepivacaine Hydrochloride; Mepivacaine Monohydrochloride; Mepivastesin; Polocaine; Scandicain; Scandicaine; Scandinibsa; Mepivacain Injektopas; 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-methyl-
Networked: 357
relevant articles (37 outcomes,
49 trials/studies)
Relationship Network
Drug Context: Research Results
Experts
1. | Casati, A:
5 articles
(09/2008 - 02/2000)
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2. | Fanelli, G:
4 articles
(09/2008 - 02/2000)
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3. | Abendschön, Nora:
3 articles
(04/2022 - 01/2020)
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4. | Baumgartner, Christine:
3 articles
(04/2022 - 01/2020)
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5. | Bergmann, Shana:
3 articles
(04/2022 - 01/2020)
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6. | Deffner, Pauline:
3 articles
(04/2022 - 01/2020)
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7. | Erhard, Michael H:
3 articles
(04/2022 - 01/2020)
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8. | Fischer, Johannes:
3 articles
(04/2022 - 01/2020)
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9. | Miller, Regina:
3 articles
(04/2022 - 01/2020)
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10. | Reiser, Judith:
3 articles
(04/2022 - 01/2020)
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Related Diseases
1. | Pain (Aches)
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2. | Pulpitis
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3. | Postoperative Pain
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4. | Wounds and Injuries (Trauma)
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5. | Edema (Dropsy)
12/01/2008
- " Mepivacaine effectively eliminated lameness within 45 minutes after injection, regardless of whether TA was also administered, whereas TA reduced lameness, edema, and concentration of synovial fluid protein after the second LPS injection, regardless of whether mepivacaine was also injected. " 09/01/2009
- " Both lidocaine and mepivacaine attenuate the increase of pulmonary arterial pressure (PAP) and lung edema development. " 11/01/1999
- " Facial edema, oral ulcers, and a cutaneous eruption following a dental procedure utilizing diflunisal and mepivacaine." 09/01/2009
- " Lidocaine and mepivacaine are more effective in reducing PAP and edema formation, but long-acting local anesthetics also inhibit ET-1 depletion and therefore have increased anti-inflammatory properties." 01/01/1988
- " Nerve fiber injury and endoneurial edema were induced by the injection of the local anesthetic 2-chloroprocaine, tetracaine, procaine, etidocaine or mepivacaine into the soft tissue and fascia surrounding the sciatic nerve of Sprague-Dawley rats. "
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