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Meningomyelocele (Myelomeningocele)

Congenital, or rarely acquired, herniation of meningeal and spinal cord tissue through a bony defect in the vertebral column. The majority of these defects occur in the lumbosacral region. Clinical features include PARAPLEGIA, loss of sensation in the lower body, and incontinence. This condition may be associated with the ARNOLD-CHIARI MALFORMATION and HYDROCEPHALUS. (From Joynt, Clinical Neurology, 1992, Ch55, pp35-6)
Also Known As:
Myelomeningocele; Acquired Meningomyelocele; Myelomeningocele, Acquired; Acquired Meningomyeloceles; Acquired Myelomeningocele; Acquired Myelomeningoceles; Meningomyelocele, Acquired; Meningomyeloceles; Meningomyeloceles, Acquired; Myeloceles; Myelomeningoceles; Myelomeningoceles, Acquired; Myelocele
Networked: 1008 relevant articles (55 outcomes, 130 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Neurogenic Urinary Bladder (Bladder, Neurogenic)
2. Hydrocephalus (Hydrocephaly)
3. Spinal Dysraphism (Spina Bifida)
4. Spinal Cord Injuries (Spinal Cord Injury)
5. Abnormal Reflex (Hyperreflexia)

Experts

1. Belfort, Michael A: 13 articles (12/2021 - 10/2013)
2. Au, Kit Sing: 13 articles (11/2020 - 08/2010)
3. Northrup, Hope: 13 articles (11/2020 - 08/2010)
4. Nejat, Farideh: 11 articles (01/2021 - 06/2006)
5. Whitehead, William E: 10 articles (07/2021 - 07/2011)
6. Shamshirsaz, Alireza A: 8 articles (07/2021 - 10/2015)
7. Morrison, Alanna C: 8 articles (11/2020 - 08/2010)
8. Flake, Alan W: 8 articles (01/2020 - 01/2007)
9. Kajbafzadeh, Abdol-Mohammad: 8 articles (01/2020 - 06/2006)
10. Meuli, Martin: 7 articles (04/2022 - 04/2013)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Meningomyelocele:
1. Type A Botulinum Toxins (Botox)FDA Link
2. cytidylyl-(3'-5')-cytidine (CpC)IBA
3. incobotulinumtoxinAFDA Link
4. Botulinum Toxins (Botulinum Toxin)IBA
5. Folic Acid (Vitamin M)FDA LinkGeneric
6. onabotulinum toxin AIBA
7. Cholinergic Antagonists (Anticholinergics)IBA
8. Anti-Bacterial Agents (Antibiotics)IBA
9. Oxygen (Dioxygen)IBA
10. MagnesiumIBA

Therapies and Procedures

1. Therapeutics
2. Injections
3. Hysterotomy
4. Ventriculoperitoneal Shunt
5. Decompression