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Meningocele

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A congenital or acquired protrusion of the meninges, unaccompanied by neural tissue, through a bony defect in the skull or vertebral column.

Also Known As:

Acquired Meningocele; Meningocele, Traumatic; Rudimentary Meningocele; Acquired Meningoceles; Herniation, Meningeal; Herniations, Meningeal; Meningeal Herniations; Meninges Herniation; Meninges Herniations; Meningocele, Acquired; Meningocele, Rudimentary; Meningoceles; Meningoceles, Acquired; Meningoceles, Rudimentary; Meningoceles, Traumatic; Rudimentary Meningoceles; Traumatic Meningocele; Traumatic Meningoceles; Herniation of Meninges; Meningeal Herniation

Networked: 179 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Dermoid Cyst (Dermoid)
2.	Pathologic Constriction (Stenosis)
3.	Meningomyelocele (Myelomeningocele)
4.	Spinal Dysraphism (Spina Bifida)
5.	Teratoma (Teratoid Tumor)

Experts

1.	Elmaci, Ilhan: 2 articles (08/2010 - 07/2008)
2.	Balak, Naci: 2 articles (08/2010 - 07/2008)
3.	Gönül, Engin: 2 articles (11/2008 - 01/2008)
4.	Cama, Armando: 2 articles (03/2006 - 05/2004)
5.	Rossi, A: 2 articles (01/2004 - 12/2001)
6.	Cama, A: 2 articles (01/2004 - 12/2001)
7.	Biancheri, R: 2 articles (01/2004 - 12/2001)
8.	Tortori-Donati, P: 2 articles (01/2004 - 12/2001)
9.	Simon, Teresa A: 1 article (12/2015)
10.	Vemuri, Sudha: 1 article (12/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Meningocele:

1.	CholesterolIBA 02/01/2007 - "Here we report a case of cholesterol granuloma arising in the posterior ethmoid sinus mimicking meningocele. " 02/01/2007 - "Cholesterol granuloma of the posterior ethmoid sinus mimicking meningocele." 11/01/2010 - "Lumbar puncture revealed cholesterol crystals in the CSF and imaging studies revealed a sickle-shaped sacrum, partial rectal stenosis, and a communicating presacral meningocele with an epidermoid-dermoid mass. "
2.	Currarino triadIBA 03/01/2014 - "When an anterior sacral meningocele is encountered, Currarino syndrome should be taken into consideration. " 07/01/2008 - "Our aim is to report the effectiveness of a simple surgical technique in the treatment of anterior sacral meningocele in the Currarino Syndrome. " 03/01/2004 - "Currarino triad as an anterior sacral meningocele." 07/01/2000 - "Posterior sagittal approach for Currarino syndrome with anterior sacral meningocele: a case report." 03/01/2014 - "Anterior meningocele pouch associated with Currarino syndrome will regresses over time following transdural ligation of its neck."
3.	Anorectal atresiaIBA 01/01/2006 - "We report the case of a 3 year old boy with a combination of anorectal malformation, sacral agenesia and anterior meningocele (Currarino's triad) and provide a review of the literature of this rare syndrome." 08/01/2010 - "If it is an anterior sacral meningocele or a solid tumor without severe anorectal malformation, it can be managed with posterior lumbar and sacral procedures. " 01/01/2009 - "Currarino's syndrome is an autosomal dominant hereditary disease known by the triad of anorectal stenosis, anterior sacral defect, and a presacral mass that is most often an anterior sacral meningocele. " 04/01/2004 - "sacrococcygeal defect, presacral mass = anterior meningocele and/or tumor, anorectal malformation) was only found in the five index patients and three further relatives. " 01/01/2003 - "A female infant is presented in whom anomalies not commonly seen in amniotic band syndrome (ABS) included non-anatomic lumbopedal union by a skin pedicle, anorectal malformation, meningocele, vertebral segmentation defects, longitudinal limb defects, vestigial feet and skin papillae. "
4.	LipomyelomeningoceleIBA 08/01/2013 - "The designed prototype successfully simulated several scenarios commonly found in pediatric neurosurgery, such as tethered spinal cord, retethered spinal cord, and fatty terminal filum, as well as meningocele, myelomeningocele, and lipomyelomeningocele. " 01/01/2013 - "Using a web-based, SB-specific electronic medical record, 10 SB clinics collected health-related information for patients diagnosed with myelomeningocele, lipomyelomeningocele, fatty filum, or meningocele. " 05/01/2004 - "Closed spinal dysraphisms with mass are represented by lipomyelocele, lipomyelomeningocele, meningocele, and myelocystocele. " 01/01/2004 - "Closed spinal dysraphisms with mass comprise lipomyelocele, lipomyelomeningocele, meningocele, and myelocystocele. " 12/01/2001 - "Closed spinal dysraphisms with mass comprise lipomyeloschisis, lipomyelomeningocele, meningocele, and myelocystocele. "
5.	Sacral agenesisIBA 05/01/2013 - "We present the first case in the literature describing a delayed presentation of terminal (posterior) meningocele in an adult patient born with sacral agenesis. " 05/01/2013 - "Meningocele is commonly found among patients with sacral agenesis. " 05/01/2013 - "A tail of sacral agenesis: delayed presentation of meningocele in sacral agenesis." 09/01/2005 - "Presacral meningocele in hereditary sacral agenesis is a complex and unusual spinal dysgenetic syndrome. " 09/01/2005 - "Presacral meningocele associated with hereditary sacral agenesis and treated surgically: evaluation in three members of the same family."
6.	Cerebrospinal fluid leakIBA 04/01/2014 - "Endoscopic endonasal repair of spontaneous sphenoid sinus lateral wall meningocele presenting with cerebrospinal fluid leak." 04/01/2007 - "Clinical examination showed a cerebrospinal fluid leak, meningeal herniation in the superior part of the middle ear, and an audible noise from her ear when she stood up due to the entrance of air into the cranium. " 01/01/2009 - "This led to the postoperative meningocele, the cerebrospinal fluid leak, and bacterial meningitis despite the successful abscess drainage. " 10/01/2006 - "The presence of a skull base defect can lead to major complications such as cerebrospinal fluid leak, meningocele, encephalocele and meningitis. " 01/01/1998 - "These included a Mondini dysplasia with persistent cerebrospinal fluid leak, an atretic mastoid with meningocele, chronic otitis media, a transverse petrous bone fracture, and a temporal bone adenoma. "
7.	PlasticsIBA 10/01/1988 - "Initially, two surgical interventions were done to remove the tumour and meningocele and three months later a gracilis plastic operation was performed successfully." 01/01/2002 - "Endoscopic endonasal plastic repair of cerebrospinal-fluid fistulas and meningocele of the anterior regions of the skull base is an effective and miniinvasive procedure as compared with transcranial interventions. " 08/01/1960 - "[Plastic closure of a retro-auricular cerebrospinal fluid fistula with cerebral prolapse and meningocele]." 04/01/1989 - "Between 1979 and 1985 plastic closures with lyophilised softened dura mater were performed in 45 children with the following indications: gastrochisis: 8; omphaloceles: 2; meningomyeloceles: 29; meningoceles: 3; diaphragmatic aplasia: 1; oesophageal atresia with tracheo-oesophageal fistula: 2. Infection as well as rejection of the implants were never observed. "
8.	Metrizamide FDA Link 04/01/1984 - "This report details our experience with CT metrizamide myelography in a case of multiple bilateral intrathoracic meningoceles." 04/01/1984 - "CT metrizamide myelography in multiple bilateral intrathoracic meningoceles." 01/01/1984 - "Metrizamide examination of traumatic lumbar nerve root meningocele." 10/01/1980 - "CSF rhinorrhea from a transclival meningocele demonstrated with metrizamide CT cisternography. " 08/01/1989 - "Metrizamide myelography disclosed a bony defect at the S2 level through which contrast material entered the pelvic cyst, confirming the diagnosis of anterior sacral meningocele. "
9.	Lateral meningocele syndromeIBA 05/01/2015 - "Lehman syndrome, or lateral meningocele syndrome, is characterized by facial dysmorphism, multiple lateral meningoceles, and skeletal abnormalities. " 02/01/2015 - "Lateral meningocele syndrome (LMS, OMIM%130720), also known as Lehman syndrome, is a very rare skeletal disorder with facial anomalies, hypotonia and meningocele-related neurologic dysfunction. " 02/01/2014 - "Lateral meningocele syndrome (LMS) is a rare hereditary connective tissue disorder characterized by pan-spinal meningoceles, specific facial dysmorphism, skeletal and soft tissue abnormalities, and hypotonia and/or muscle weakness. " 03/01/2008 - "This article provides a comprehensive review of syndromes, disorders, and maternal risk factors associated with NTDs, such as Currarino syndrome, sacral defect with anterior meningocele, Jarcho-Levin syndrome (spondylocostal dysostosis), lateral meningocele syndrome, neurofibromatosis type I, Marfan syndrome, and hyperthermia. "
10.	Caudal regression syndromeIBA 11/01/2010 - "Cerebrospinal fluid analysis confirmed bacterial meningitis and a spinal magnetic resonance imaging scan revealed a dermal sinus tract with an anterior spinal meningocele, caudal regression syndrome, and a tethered spinal cord. " 03/01/2011 - "Images of the normal spinal cord, normal variants (ventriculus terminalis, cyst of filum terminale) and spinal cord abnormalities (myelomeningocele, meningocele, diastematomyelia, tethered spinal cord and caudal regression syndrome) are presented. " 01/01/2011 - "The cases of diastematomyelia, myelomeningocele, tethered cord, caudal regression syndrome, anterior meningocele, cystic sacrococcygeal teratoma and syringohydromyelia are demonstrated." 07/01/2000 - "US allows detection of congenital malformations, such as myelocele or myelomeningocele, spinal lipoma, dorsal dermal sinus, tight filum terminale syndrome, diastematomyelia, terminal myelocystocele, lateral meningocele, caudal regression syndrome, and hydromyelia or syringomyelia. "

Therapies and Procedures

1.	Transplants (Transplant) 05/01/1994 - "After any existing meningoceles or meningoencephaloceles have been cauterized or amputated, small grafts of autogenous fascia or cartilage are used to plug defects found. " 01/01/2014 - "Surgical treatment via a right thoracotomy with primary repair of the meningocele and spinal fusion with fibula graft resulted in good outcome. " 05/01/2003 - "The fistula between the meningocele and the spinal subarachnoid space was obliterated with multiple fat grafts harvested from the abdomen. " 12/11/1969 - "Posterior ilio-psoas transplants for paralytic dislocation of the hips in a child with a lumbo-sacral meningocele." 05/01/1997 - "A wide range of surgery was encompassed, with neurosurgery accounting for 17 (2%) of the total operations: compound depressed fractured skull, 5; intracranial pressure monitor, 2; burr holes for acute head injury and chronic subdural hematoma, 2; skull osteomyelitis debridement, 1; rib-graft cranioplasty, 2; scalp rotation flap, 1; congenital myelomeningocele, 2; occipital meningocele, 1; craniofacial approach to Le Fort III fracture, 1. A broad range of neurosurgical procedures have been performed. "
2.	Thoracotomy 05/01/2008 - "Because of the long-existing hemithoracic meningocele, we assumed that this patient actually had only 1 functional lung, and so, left-sided thoracotomy with resection of the meningocele and closure of the defect included a high operative mortality. " 08/01/1992 - "The meningocele was diagnosed preoperatively and resected surgically by left thoracotomy. " 09/01/1990 - "With the preoperative diagnosis established and the severity of the meningocele known, the surgeons safely employed a subpleural approach at thoracotomy." 01/01/2014 - "Surgical treatment via a right thoracotomy with primary repair of the meningocele and spinal fusion with fibula graft resulted in good outcome. "
3.	Spinal Fusion (Spondylosyndesis) 03/01/2003 - "For this reason, spinal fusion should have been conducted during surgery for the patient's meningocele." 11/01/1985 - "The meningocele was excised to permit anterior spinal cord decompression and spinal fusion. " 01/01/2014 - "Surgical treatment via a right thoracotomy with primary repair of the meningocele and spinal fusion with fibula graft resulted in good outcome. "
4.	Laminectomy 02/01/2008 - "After posterior laminectomy and dural opening, communication between meningocele and intrathecal compartment was obliterated. " 03/01/2003 - "A wide laminectomy from T2 to T5 was performed and the meningocele was resected. " 10/01/1999 - "Posterolateral extradural approach with laminectomy was done and dural plasty to close the connection between the meningocele and the subarachnoidal space was carried out. " 08/01/1996 - "More recently decompressive laminectomy, subarachnoid space reconstruction and formation of surgical meningocele have been used. " 10/01/1990 - "Pseudo-meningocele post-laminectomy is a non-frequent complication of this surgical technique. "
5.	Ligation 04/01/2003 - "The first patient underwent excision of her large sacral meningocele and simple ligation of the neck, resulting in resolution of all her associated symptoms. " 11/01/1999 - "Surgical repair was performed by dissection of the base of the meningocele followed by ligation. " 10/01/1993 - "Surgical treatment through the posterior transsacral approach failed, because the neck and orifice of the meningocele were too large to perform a simple neck ligation. " 07/01/2008 - "We performed a posterior procedure via lumbar and sacral partial laminectomy and transdural ligation of the neck of the meningocele mass. " 12/01/2013 - "After the final diagnosis of anterior sacral meningocele was established, a second operation was performed for the ligation of the cyst neck through a posterior approach. "