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Medroxyprogesterone

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(6 alpha)-17-Hydroxy-6-methylpregn-4-ene-3,20-dione. A synthetic progestational hormone used in veterinary practice as an estrus regulator.

Also Known As:

17 alpha-Hydroxy-6 alpha-Methylprogesterone; Adgyn Medro; Strakan Brand of Medroxyprogesterone; 17 alpha Hydroxy 6 alpha Methylprogesterone; Medroxyprogesterone Strakan Brand; Methylhydroxyprogesterone; Pregn-4-ene-3,20-dione, 17-hydroxy-6-methyl-, (6alpha)-

Networked: 274 relevant articles (20 outcomes, 44 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Polycyclic Compounds: 56
- Steroids: 18537
  - Pregnanes: 3
    - Pregnenes
      - Pregnenediones
        Progesterone: 8924
        Medroxyprogesterone: 274
        Medroxyprogesterone Acetate: 1694
        divina: 2
        ACM protocol
        klimaxil
        medroxyprogesterone-17-hemisuccinate
        VAC-MAP protocol

Experts

1.	Herold, Betsy C: 3 articles (01/2014 - 12/2005)
2.	Saaresranta, Tarja: 3 articles (01/2005 - 02/2004)
3.	Polo, Olli: 3 articles (01/2005 - 02/2004)
4.	Arnes, M: 2 articles (03/2014 - 12/2003)
5.	Straume, B: 2 articles (03/2014 - 12/2003)
6.	Yin, Yuzhi: 2 articles (03/2012 - 09/2005)
7.	Glazer, Robert I: 2 articles (03/2012 - 09/2005)
8.	Kopelovich, Levy: 2 articles (03/2012 - 09/2005)
9.	Chlebowski, Rowan T: 2 articles (02/2012 - 10/2009)
10.	Aragaki, Aaron K: 2 articles (02/2012 - 10/2009)

Related Diseases

1.	Chronic Obstructive Pulmonary Disease (COPD) 01/01/2005 - "Medroxyprogesterone improves nocturnal breathing in postmenopausal women with chronic obstructive pulmonary disease." 10/01/2004 - "Significant improvement in arterial blood gas and ventilatory parameters was reported in COPD patients after acetazolamide and medroxyprogesterone treatment; however, with no improvement in survival or quality of life, the place of these drugs in therapy remains unknown." 10/01/2004 - "Trials are reviewed evaluating ventilatory parameters with acetazolamide and/or medroxyprogesterone in patients with COPD. " 11/01/2002 - "Combined treatment with acetazolamide and medroxyprogesterone in chronic obstructive pulmonary disease patients." 08/01/1986 - "Previous studies have shown that some patients with chronic obstructive lung disease and hypercapnia will respond to medroxyprogesterone with improvement in arterial blood gases. "
2.	Neoplasms (Cancer) 01/01/1992 - "In the first approach medroxyprogesterone dosage increased up to 400 mg a day, achieved better results in curative as well as adjuvant treatment of advanced or early gynecologic cancers. " 08/01/1986 - "In this selected group of patients, oral medroxyprogesterone at a dose level of 400 mg/day appeared to provide a significant frequency of tumor response." 02/01/1981 - "Inhibition of tumor growth, vascularization, and collagenolysis in the rabbit cornea by medroxyprogesterone." 10/02/1976 - " In December 1974, a tumor was discovered and treated with medroxyprogesterone 250 mg/day. " 01/01/1991 - "In spite of the fact that progestagene receptors were not evidenced in two of our cases, one presented complete remission of the tumor after treatment with medroxyprogesterone. "
3.	Endometriosis (Adenomyosis) 01/01/2013 - "Treatment with Medroxyprogesterone was 100% effective in terms of relapse, while Triptorelinum could not prevent recurrence of endometriosis." 07/01/2000 - "Efficacy of medroxyprogesterone treatment in infertile women with endometriosis: a prospective, randomized, placebo-controlled study." 12/01/1961 - " The 19-norsteroids and medroxyprogesterone are being used in the treatment of endometriosis. " 04/01/2007 - "We collected the samples of endometrium from patients with endometriosis before operation or after insertion of levenorgestrel releasing intrauterine system (LNG-IUS), administration of oral medroxyprogesterone (MPA), or injection of gonadotrophic hormone releasing hormone agonist (GnRHa). " 04/01/2007 - "To investigate the apoptosis-related mechanisms of levenorgestrel-releasing intrauterine system (LNG-IUS), oral medroxyprogesterone (MPA), and injective gonadotrophic hormone releasing hormone agonist (GnRHa) on eutopic endometrium of patients with endometriosis. "
4.	Amenorrhea 12/01/1997 - "Uncomplicated amenorrhea in PCOS is managed with monthly or bimonthly administration of medroxyprogesterone. " 06/01/1994 - "Cyclic medroxyprogesterone increased spinal bone density in physically active women experiencing amenorrhea or ovulatory disturbances. " 04/15/1964 - "PROLONGED AMENORRHEA FOLLOWING MEDROXYPROGESTERONE." 10/01/1999 - "[Evaluation of safety in Chinese women with amenorrhea following injection of depot-medroxyprogesterone for contraception]." 05/01/1995 - "The role of orally administered medroxyprogesterone at a dose of 10 mg per day, 10 days per month, in improving BMD in teenage girls with hypothalamic amenorrhea or oligomenorrhea remains to be established. "
5.	Respiratory Insufficiency (Respiratory Failure) 02/01/2004 - "This case documents successful control of chronic respiratory failure with medroxyprogesterone in a postmenopausal woman during 1-year follow-up." 02/01/2004 - "Medroxyprogesterone improves cardiac autonomic control in postmenopausal women with respiratory insufficiency." 08/01/2000 - "Prolonged endocrine responses to medroxyprogesterone in postmenopausal women with respiratory insufficiency." 09/01/2002 - "This case documents the treatment of chronic type II respiratory failure secondary to central hypoventilation with medroxyprogesterone, a new treatment option." 07/01/1999 - "Two of these patients appeared to stabilise with no appreciable change clinically or in lung function on medroxyprogesterone and/or tamoxifen, but the remaining patients all deteriorated with two dying of respiratory insufficiency and one of infection following lung transplantation. "

Related Drugs and Biologics

1.	Gases
2.	Estrogens (Estrogen)
3.	Acetazolamide (Diamox)
4.	Levonorgestrel (Plan B)
5.	Oral Contraceptives
6.	Estradiol (Estrace)
7.	Fluorouracil (Carac)
8.	Oxygen
9.	Collagenases (Collagenase)
10.	Mitomycin (Mitomycin-C)

Related Therapies and Procedures

1.	Aftercare (After-Treatment)
2.	Intrauterine Devices (Intrauterine Device)
3.	Hormone Replacement Therapy (Therapy, Hormone Replacement)
4.	Injections
5.	Contraception (Birth Control)