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Mechlorethamine (Nitrogen Mustard)

A biologic alkylating agent that exerts its cytotoxic effects by forming DNA ADDUCTS and DNA interstrand crosslinks, thereby inhibiting rapidly proliferating cells. The hydrochloride is an antineoplastic agent used to treat HODGKIN DISEASE and LYMPHOMA.
Also Known As:
Nitrogen Mustard; Chlormethine; Mustargen; Mustine; Bis(2-chloroethyl)methylamine; Caryolysine; Cloramin; Embichin; Mechlorethamine Hydrochloride; Mechlorethamine Hydrochloride N-Oxide; Mechlorethamine N-Oxide; Methylchlorethamine; Mitomen; NSC-10107; NSC-762; Nitrogranulogen; Nitromin; Hydrochloride N-Oxide, Mechlorethamine; Hydrochloride, Mechlorethamine; Mechlorethamine Hydrochloride N Oxide; Mechlorethamine N Oxide; N-Oxide, Mechlorethamine Hydrochloride; N-Oxide, Nitrogen Mustard; NSC 10107; NSC 762; NSC10107; NSC762; Nitrogen Mustard N Oxide; Chlorethazine; Mechlorethamine Oxide; Nitrogen Mustard N-Oxide; Ethanamine, 2-chloro-N-(2-chloroethyl)-N-methyl-
Networked: 1690 relevant articles (74 outcomes, 158 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Laskin, Jeffrey D: 17 articles (05/2021 - 01/2011)
2. Laskin, Debra L: 15 articles (01/2021 - 01/2011)
3. Gow, Andrew J: 12 articles (01/2021 - 01/2011)
4. Tewari-Singh, Neera: 10 articles (01/2022 - 10/2012)
5. Venosa, Alessandro: 10 articles (01/2021 - 12/2012)
6. Agarwal, Rajesh: 9 articles (01/2022 - 10/2012)
7. Malaviya, Rama: 9 articles (11/2020 - 12/2012)
8. Querfeld, Christiane: 8 articles (07/2022 - 09/2020)
9. Geskin, Larisa J: 8 articles (05/2022 - 05/2020)
10. Kim, Youn H: 7 articles (07/2022 - 01/2003)

Related Diseases

1. Hodgkin Disease (Hodgkin's Disease)
2. Neoplasms (Cancer)
3. Mycosis Fungoides
4. Lymphoma (Lymphomas)
5. Leukemia

Related Drugs and Biologics

1. Procarbazine (Matulane)
2. Prednisone (Sone)
3. Vincristine (Oncovin)
4. Doxorubicin (Adriamycin)
5. Bleomycin (Blenoxane)
6. Vinblastine (Vinblastine Sulfate)
7. Dacarbazine (DIC)
8. Cyclophosphamide (Cytoxan)
9. Lomustine (CCNU)
10. Chlorambucil (Leukeran)

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Therapeutics
3. Radiotherapy
4. Combination Drug Therapy (Combination Chemotherapy)
5. Salvage Therapy