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Mastocytosis

A rare neoplastic disorder characterized by a clonal proliferation of MAST CELLS, associated with KIT-D816 mutations, and accompanied by aberrant mast cell activation. The abnormal increase of MAST CELLS may occur in only the skin (MASTOCYTOSIS, CUTANEOUS), in extracutaneous tissues involving multiple organs (MASTOCYTOSIS, SYSTEMIC), or in solid tumors (MASTOCYTOMA).
Networked: 940 relevant articles (58 outcomes, 79 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Anaphylaxis (Anaphylactic Shock)
2. Hypersensitivity (Allergy)
3. Systemic Mastocytosis
4. Neoplasms (Cancer)
5. Osteoporosis

Experts

1. Valent, Peter: 43 articles (01/2022 - 02/2002)
2. Akin, Cem: 42 articles (01/2022 - 01/2002)
3. Metcalfe, Dean D: 39 articles (01/2022 - 01/2002)
4. Hermine, Olivier: 25 articles (04/2022 - 04/2008)
5. Arock, Michel: 25 articles (01/2022 - 02/2002)
6. Bonadonna, Patrizia: 21 articles (01/2022 - 08/2010)
7. Horny, Hans-Peter: 21 articles (01/2022 - 02/2002)
8. Sperr, Wolfgang R: 21 articles (01/2022 - 06/2002)
9. Orfao, Alberto: 19 articles (06/2022 - 02/2002)
10. Brockow, Knut: 19 articles (01/2022 - 01/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Mastocytosis:
1. Tryptases (Tryptase)IBA
2. Omalizumab (Xolair)FDA Link
3. Histamine (Histamine Dihydrochloride)FDA Link
4. Histamine Antagonists (Antihistamines)IBA
5. Immunoglobulin E (IgE)IBA
6. AllergensIBA
7. masitinibIBA
8. Epinephrine (Adrenaline)FDA LinkGeneric
9. Diphosphonates (Bisphosphonates)IBA
10. Immunoglobulin G (IgG)IBA

Therapies and Procedures

1. Therapeutics
2. Immunotherapy
3. Drug Therapy (Chemotherapy)
4. Bone Marrow Transplantation (Transplantation, Bone Marrow)
5. Anesthesia