Mastitis

02/15/2021 - "When this issue has been addressed, the available evidence on the best treatment practice of Gram-negative-caused mastitis cases can be applied properly, reducing the volume of antibiotic treatments with limited expected effect. "
01/01/2021 - "Seeking safe and effective mastitis prevention strategies is urgent since food safety and drug residues in milk remain an enormous concern, despite the contribution of antibiotics to control mastitis. "
05/19/2017 - "Antibiotics are often used in the treatment of mastitis, but have not been popular or proven effective as a preventative agent. "
01/01/2016 - "Infectious mastitis was observed in three patients (3%), who were treated successfully with antibiotics. "
07/01/2001 - "The efficacy of an intramammary antibiotic dry cow preparation with significant gram-negative spectrum (product A; Leo Red Dry Cow, Leo Animal Health, UK) was compared with a product with no gram-negative efficacy (product B; Orbenin Extra DC, Pfizer Ltd, UK) as assessed by control of coliform mastitis in the first 100 d of the lactation. "

05/01/2019 - "Multiple factors account for the lack of protection, including inadequate vaccine targets, high diversity among mastitis-provoking strains, cow-to-cow variation in immune response, and a failure to elicit an immune response that is appropriate for protection against a highly complex pathogen. "
11/01/1993 - "These vaccines doubtless will prove beneficial on well managed dairies that have eradicated contagious mastitis pathogens. "
07/01/1989 - "coli J5 vaccine is protective against natural challenge to gram-negative bacteria, and reduces the incidence of clinical gram-negative mastitis in dairy cows during the first three months of lactation."
01/01/2002 - "Potential mechanism of action of J5 vaccine in protection against severe bovine coliform mastitis."
12/01/1996 - "To assess the efficacy of a new staphylococcal mastitis vaccine under commercial dairying conditions. "

01/01/2020 - "To evaluate the protective effects of ATC on mastitis and investigate its active mechanism, a lipopolysaccharide (LPS)-induced rat mastitis model was used in two experiments. "
12/01/2022 - "Lipopolysaccharide (LPS) is an important inflammatory and infected factor of bacterial mastitis, which treated bovine mammary epithelial cells (MAC-T) in our previous studies, as mastitis cells model in vitro. "
12/01/2021 - "In this study, primary goat mammary epithelial cells (GMECs) were treated with 10 μg/mL lipopolysaccharide (LPS) for 14 d to mimic the in vivo mastitis environment. "
11/19/2021 - "To elucidate whether isolated perfused bovine udders can be used to study early inflammatory events of mastitis, 1 mg of lipopolysaccharide (LPS) was instilled into quarters of 10 isolated perfused bovine udders. "
01/01/2021 - "The purpose of this study was to investigate the protective effect and mechanism of MNK against lipopolysaccharide (LPS)-induced mastitis in vitro. "

12/01/2019 - "We also conclude that, although ceftiofur is 100% effective in vitro, when used in ewes with mastitis, the efficacy did not exceed 70%, and was more efficient when administered via the intramammary route."
08/01/2004 - "Ceftiofur should be effective against a wide range of contagious and environmental mastitis pathogens. "
12/01/2011 - "The objective of this study was to evaluate the efficacy of intramammary treatment with ceftiofur hydrochloride of nonsevere, clinical coliform mastitis. "
10/01/2002 - "The objectives of this study were to determine the efficacy of intramuscular administration of ceftiofur to reduce the incidence of case-related death and culling following severe clinical mastitis in lactating dairy cattle. "
12/01/2011 - "Randomized clinical trial to evaluate the efficacy of a 5-day ceftiofur hydrochloride intramammary treatment on nonsevere gram-negative clinical mastitis."

12/30/2021 - "Antimicrobial Selection for the Treatment of Clinical Mastitis and the Efficacy of Penicillin Treatment Protocols in Large Estonian Dairy Herds."
01/01/2003 - "Efficacy of targeted 5-day combined parenteral and intramammary treatment of clinical mastitis caused by penicillin-susceptible or penicillin-resistant Staphylococcus aureus."
10/01/1947 - "Efficacy of intramammary infusion with penicillin and diluents on streptococcic mastitis."
03/01/1955 - "[Puerperal mastitis in the penicillin era; studies on 1100 cases in Leipzig]."
01/01/1946 - "Studies in infectious mastitis; penicillin as a therapeutic agent."

06/01/2001 - "Efficacy of a new premilking teat disinfectant containing a phenolic combination for the prevention of mastitis."
01/01/1993 - "The objective of this study was to evaluate the efficacy of a premilking teat disinfectant for the prevention of mastitis in dairy cows under natural exposure conditions. "
04/01/2013 - "Defining standardized protocols for determining the efficacy of a postmilking teat disinfectant following experimental exposure of teats to mastitis pathogens."
09/01/2009 - "These findings call for use of udder disinfectants and improved milking hygiene as intervention strategies to control mastitis on the smallholder dairy farms in Tanzania."
05/01/2019 - "The objective of this study was to screen commercial teat disinfectants for inhibition against mastitis-associated bacteria isolated from various types of milk samples. "

11/01/2014 - "Efficacy of standard vs. extended intramammary cefquinome treatment of clinical mastitis in cows with persistent high somatic cell counts."
02/01/1997 - "This study supported the efficacy of cefquinome in the treatment of clinical coliform mastitis in dairy cows."
01/01/2017 - "Efficacy of Cefquinome against Escherichia coli Environmental Mastitis Assessed by Pharmacokinetic and Pharmacodynamic Integration in Lactating Mouse Model."
08/01/2013 - "Efficacy of extended cefquinome treatment of clinical Staphylococcus aureus mastitis."
08/01/2011 - "Efficacy of conventional and extended intra-mammary treatment of persistent sub-clinical mastitis with cefquinome in lactating dairy cows."

02/01/2018 - "Yet, the outstanding clinical and bacteriological cure rates obtained for enro-C for nonsevere cases of mastitis is superior to previously reported data for parenteral enrofloxacin and other antibacterial-intramammary treatments. "
04/09/2015 - "Enrofloxacin concentrations were effective in the entire glandular tissue against the main pathogens causing mastitis in sheep. "
06/27/2015 - "The aim of this double-blinded field trial was to investigate the efficacy of enrofloxacin compared with placebo, with a special focus on survival, in dairy cows with acute clinical mastitis caused by E. "
06/27/2015 - "Efficacy of enrofloxacin for the treatment of acute clinical mastitis caused by Escherichia coli in dairy cows."
05/01/2010 - "Efficacy of enrofloxacin in the treatment of naturally occurring acute clinical Escherichia coli mastitis."

08/01/1994 - "The mice vaccinated with FnBP fusion proteins showed a decreased number of bacteria recovered from the mammary glands and significantly reduced cases of severe mastitis. "
12/06/2022 - "In this study, EC and pH values in milk were significantly increased (p < 0.0001), whereas fat (p < 0.04) and protein (p < 0.0002) significantly decreased in animals with subclinical mastitis in comparison to healthy animals. "
01/01/2022 - "The present study was designed to evaluate the association of polymorphisms in bovine trafficking protein particle complex subunit 9 (TRAPPC9) and cluster of differentiation 4 (CD4) genes with milk production and mastitis resistance phenotypic traits in a different cattle population. "
01/01/2021 - "In this study, changes in the abundance of proteins of milk and serum, caused by naturally occurring mastitis have been characterised by proteomics using a quantitative approach and both subclinical and clinical cases of mastitis have been investigated. "
01/01/2021 - "The study was based on records on milk yield (MY), protein yield (PY), fat yield (FY), somatic cell score (SCS), and mastitis (MAST) from 73,695 first-lactation dairy cows in 130 Danish herds applying systematic crossbreeding programs. "

06/11/2023 - "As a result, the extracts of pomegranate flowers showed a high antioxidant and antibacterial potential against the examined mastitis pathogens."
03/30/2020 - "The efficacy of mastitis treatments affected the reproduction indices: in cows requiring prolonged treatment with antioxidants, a shorter time to first insemination was needed than in other groups (p <  0.05). "
03/01/2008 - "In vitro and in vivo studies suggest that the use of antioxidants and other protective compounds in mastitis control programs is worth investigating, because they may aid in alleviating damage to secretory cells and thus reduce subsequent milk loss."
03/29/2022 - "To alleviate oxidative stress and subsequent mastitis, antioxidants are supplemented to dairy cattle from an external source. "
08/01/2021 - "In contrast, total antioxidant capacity and MDA concentration in subclinical mastitis cows without spontaneous cure significantly increased with time (P < 0.05). "

03/01/2003 - "Ultimately, the best outcome of mastitis therapy is a positive effect on the amount of marketed milk harvested and long-term survival of the cow. "
11/03/2020 - "The obtained data can be very helpful in assessing internal mastitis scenarios and the effect of measures and therapies."
02/01/1991 - "Results from these preliminary in vitro data suggest that rBoIFN-gamma therapy may modulate mammary gland neutrophil functions in vivo and possibly facilitate the rapid clearance of mastitis-causing pathogens mammary glands during the periparturient period."
06/01/2021 - "Dry cow therapy (DCT) can be an effective treatment of mastitis that has not responded to conventional treatment during lactation. "
12/01/2019 - "A systematic review and network meta-analysis were conducted to assess the relative efficacy of antimicrobial therapy for clinical mastitis in lactating dairy cattle. "

11/03/2023 - "The Initial Efficacy of Comprehensive Treatment of External Treatment of Traditional Chinese Medicine on Acute Mastitis During Lactation and its Influence on Patients' Symptoms."
01/01/2021 - "The purpose of this study was to explore the relationship between acute mastitis and the constitution of traditional Chinese medicine (TCM) and the potential risk factors of acute mastitis in Chinese breastfeeding mothers. "
09/26/2021 - "Treatment of bilateral granulomatous lobular mastitis during lactation with traditional Chinese medicine: A case report."
08/10/2021 - "(genus Hypericum, family Hypericaceae) has a long history as a traditional Chinese medicine, which was traditionally used for the treatment of emotional distress, cardiothoracic depression, and acute mastitis. "
05/01/2021 - "A set of 60 cases diagnosed with non-lactational mastitis who had received surgical treatment at the Department of Thoracic and Breast Surgery of Xiamen Hospital of Traditional Chinese Medicine (Xiamen, China) between July 2017 and June 2019 were included. "

01/01/2008 - "Adult sheep were the most common age group treated with injectable antimicrobials and the most frequent reason for injectable antimicrobial use was mastitis followed by respiratory problems. "
03/01/2016 - "In low-consuming herds, most antimicrobials were being used for dry-cow therapy, whereas in high-consuming herds, most antimicrobials were being used as injectable or intramammary mastitis therapy. "
10/09/2022 - "Comparison of the Efficacy of Intramammary or Injectable Antibiotic Administration against Staphylococcal Mastitis in Ewes."
01/21/2023 - "Intramammary injections of rifaximin have a beneficial effect on dairy cow mastitis, especially for mastitis caused by E. "
07/25/2022 - "The self-reported adoption of culture-based mastitis treatment practices was statistically significantly associated with higher numbers of injectable and intramammary doses of antibiotics used on the participants' farms. "

06/01/2016 - "Previous studies have shown the efficacy of oral administration of selected lactobacilli strains to treat mastitis. "
03/01/2016 - "Previous studies have shown that oral administration of lactobacilli can be an efficient approach to treat lactational infectious mastitis. "
11/01/2023 - "These findings suggest that the oral administration of LPSpa may prevent mastitis by increasing the concentration of GBD1 in milk."
01/01/2022 - "Furthermore, the abundance of Stenotrophomonas was increased in the rumen of SARA cows, and mastitis was induced by oral administration of Stenotrophomonas in lactating mice. "
01/01/2022 - "After oral administration of probiotics, the counts of bacteria in the milk of healthy people and mastitis patients were both significantly reduced (in healthy people: MD: -0.19, 95% CI: -0.23 to -0.16, p<0.00001; in mastitis patients: MD: -0.89, 95% CI: -1.34 to -0.43, p = 0.0001). "

12/01/2004 - "Based on the widespread use of homeopathy in treatment of animal disease and the poor documentation of its possible effects and consequences, a clinical trial was carried out in order to evaluate the efficacy of homeopathy in treatment of clinical mastitis in dairy cows and a design for clinical studies on homeopathic treatment, taking into account the guidelines for randomized-clinical trials (RCT) as well as the basic principles of homeopathy. "
01/01/2018 - "The study results implied that the effectiveness of individualised homeopathy does not go beyond a placebo effect and successful treatment is highly dependent on the specific mastitis pathogen. "
01/01/2018 - "Based on the widespread use of homeopathy in dairy farm practice when treating mastitis, a blind randomised controlled trial (RCT) was conducted to assess the effectiveness of homeopathic treatment of clinical mastitis on four dairy farms. "
07/13/2022 - "Persistence of Staphylococcus spp. in milk from cows undergoing homeopathy to control subclinical mastitis."
06/01/2017 - "Dairy cows with acute mastitis were randomly allocated to homeopathy (n = 70) or placebo (n = 92), for a total of 162 animals. "