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Mansonelliasis

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Infection with nematodes of the genus MANSONELLA. Symptoms include pruritus, headache, and articular swelling.

Also Known As:

Mansonella perstans Infections; Mansonellosis; Infection, Mansonella perstans; Infections, Mansonella perstans; Mansonella perstans Infection; Mansonelliases; Mansonelloses; perstans Infection, Mansonella; perstans Infections, Mansonella

Networked: 20 relevant articles (1 outcomes, 3 trials/studies)

Relationship Network

Disease Context: Research Results

Parasitic Diseases: 854
- Helminthiasis: 304
  - Nematode Infections: 547
    - Secernentea Infections
      - Spirurida Infections: 3
        Filariasis: 1118
        Mansonelliasis: 20

Related Diseases

1.	Onchocerciasis
2.	Body Weight (Weight, Body)
3.	Infection
4.	Loiasis
5.	Helminthiasis (Helminthiases)

Experts

1.	Nutman, Thomas B: 3 articles (10/2009 - 01/2003)
2.	Klion, Amy D: 2 articles (10/2009 - 01/2003)
3.	Konate, Siaka: 2 articles (10/2009 - 07/2009)
4.	Diallo, Abdallah A: 2 articles (10/2009 - 07/2009)
5.	Coulibaly, Yaya I: 2 articles (10/2009 - 07/2009)
6.	Doumbia, Salif S: 2 articles (10/2009 - 07/2009)
7.	Coulibaly, Siaka Y: 2 articles (10/2009 - 07/2009)
8.	Antony, Justin S: 1 article (11/2014)
9.	Kreidenweiss, Andrea: 1 article (11/2014)
10.	Bélard, Sabine: 1 article (11/2014)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Mansonelliasis:

1.	Ivermectin (Mectizan)FDA Link 12/01/2003 - "Impact of long-term ivermectin (Mectizan) on Wuchereria bancrofti and Mansonella perstans infections in Burkina Faso: strategic and policy implications." 12/01/1999 - "Ivermectin treatment of mansonellosis in Trinidad." 09/01/1998 - "Single dose of ivermectin to control mansonellosis in Trinidad: a four-years follow-up study." 12/01/1996 - "Ivermectin treatment of mansonellosis in Blanchisseuse, Trinidad, West Indies." 03/01/1993 - "Efficacy of ivermectin in the treatment of concomitant Mansonella perstans infections in onchocerciasis patients."
2.	Doxycycline (Vibramycin)FDA LinkGeneric 10/08/2009 - "A randomized trial of doxycycline for Mansonella perstans infection." 01/21/2010 - "Doxycycline for Mansonella perstans infection."
3.	Albendazole (Albenza)FDA Link 03/01/2009 - "A randomised, double-blind field trial of ivermectin alone and in combination with albendazole for the treatment of Mansonella perstans infections in Uganda." 03/01/2009 - "The effect of a single dose of ivermectin alone (150-200microg/kg body weight) or in combination with albendazole (total of 400mg) in Mansonella perstans infection was assessed in a randomised, double-blind field trial in two endemic communities in Mukono and Luwero districts of Uganda. "
4.	Anti-Bacterial Agents (Antibiotics)IBA 11/15/2014 - "Before generalizing the use of antibiotics for mansonellosis, further clarification of the obligatory nature of the endosymbiosis in this nematode is needed. " 08/01/2003 - "The absence of Wolbachia in both filarial species therefore discourages the use of antibiotics as an adjunct or alternative approach to current treatment concepts for both loiasis and mansonelliasis perstans."
5.	Collagen Type IV (Type IV Collagen)IBA 09/01/1994 - "This pattern of reactivity was characteristic for onchocerciasis: sera from patients with mansonellosis reacted strongly with collagen type IV but only weakly with laminin. "
6.	Interleukin-13IBA 12/16/2010 - "Maternal Mansonella perstans infection was associated with higher interleukin (IL)-10 responses to both immunogens but no reduction in gamma interferon (IFN-γ), IL-5 and IL-13 responses; other maternal helminth infections showed little effect. "
7.	CytokinesIBA 07/15/2009 - "Cytokines were measured from plasma and Ag-stimulated whole blood from individuals with Wuchereria bancrofti and/or Mansonella perstans infections (Fil(+); n = 19) and those without evidence of filarial infection (Fil(-); n = 19). "
8.	SaponinsIBA 12/01/1990 - "Comparison of thick blood smear and saponin haemolysis for the detection of Loa loa and Mansonella perstans infections."
9.	Retinaldehyde (Retinal)IBA 11/01/2002 - "A case of Mansonella perstans infection with visual impairment and a retinal lesion is described. "
10.	NeurotoxinsIBA 06/01/2013 - "Further research is recommended on the association of Nodding Syndrome with onchocerciasis/mansonelliasis and neurotoxins in plant materials used for food."