Maneb

03/01/2014 - "This study examined whether exposure of mice to concentrated ambient ultrafine particles (CAPS; <100nm diameter) during the first two weeks of life would alter susceptibility to induction of the Parkinson's disease phenyotype (PDP) in a pesticide-based paraquat and maneb (PQ+MB) model during adulthood utilizing i.p. "
06/01/2011 - "Epidemiological and in vivo studies have demonstrated that exposure to the pesticides paraquat (PQ) and maneb (MB) increase the risk of developing Parkinson's disease (PD) and cause dopaminergic cell loss, respectively. "
09/01/2008 - "The present study was undertaken to investigate the gene expression patterns of the striatum of control and maneb + paraquat-induced Parkinson's disease (PD) phenotype in mouse to identify the differentially expressed transcripts. "
06/10/2005 - "This study analyzed the role of oxidative stress as a mechanism of the dopaminergic neurotoxicity produced by the combined paraquat and maneb model of the Parkinson disease phenotype. "
08/01/2003 - "The current study tested this hypothesis by exposing C57BL/6 mice that were 6 weeks, 5 months or 18 months old to the herbicide paraquat, the fungicide maneb or paraquat + maneb, a combination that produces a Parkinson's disease phenotype in young adult mice. "

01/01/2004 - "Maneb, a widely used fungicide, has been associated with Parkinsonism in humans. "
08/01/1994 - "To our knowledge, this is the second report on parkinsonism associated with exposure to maneb. "
05/01/2013 - "Neuroprotective role of Withania somnifera root extract in maneb-paraquat induced mouse model of parkinsonism."
01/01/2003 - "Manganese ethylene-bis-dithiocarbamate (Mn-EBDC) is the major active element of maneb, a pesticide linked to parkinsonism in certain individuals upon chronic exposure. "
01/01/1996 - "Agricultural exposure to the organomanganese fungicide MANEB (manganese-ethylene-bis-dithiocarbamate) may induce an extrapyramidal syndrome resembling parkinsonism. "

01/01/1980 - "Dose-response relationship in delayed type contact sensitivity with maneb: an experimental model of "simple chemicals"."
08/01/1988 - "Contact dermatitis due to Ziram and Maneb."
01/01/1979 - "Three cases of contact dermatitis caused by Maneb, manganous-ethylene-bis (dithiocarbamate), are described. "
07/05/1976 - "Experimental study on contact dermatitis caused by dithiocarbamates maneb, mancozeb, zineb, and their related compounds."
03/01/1987 - "In particular case reports are mentioned on contact dermatitis due to Metham-sodium, Dazomet, Zineb and Maneb, Benomyl, Captan, Propachlor, Phenmedipham, 2,4-D and 2,4,5-T, Dichlorvos, Parathionmethyl, Trichlorfon. "

08/01/1980 - "Tumor incidence was 94% in controls and 98% in maneb-treated newts. "
08/01/1980 - "No differences in tumor incidence were found between control and maneb-treated animals of either population. "
04/30/1979 - "Percutaneous exposure of adult newts to the fungicide manganese ethylenebisdithiocarbamate (maneb) at 3 concentration levels (0.5, 2.5 and 5.0 ppm) for a total of 19.23 weeks did not result in the induction of any neoplasms."
06/15/2003 - "Exposure of highly purified NK cells to 10 microM atrazine, maneb, or metiram inhibited K562 tumor cell lysis by 63+/-25, 95+/-4, and 50+/-6%, respectively, after a 24 h exposure and by 83+/-21, 70+/-39, and 48+/-41% after a 6-day exposure. "
06/15/2003 - "In this study, we examined the effects of atrazine, maneb, metiram, zineb, and ziram on the ability of human NK cells to lyse tumor cells. "

01/01/2012 - "In the current studies we have analyzed the ability of maneb and paraquat, separately and together, to induce synucleinopathy and tauopathy in wild type mice. "
01/01/2012 - "Paraquat, but not maneb, induces synucleinopathy and tauopathy in striata of mice through inhibition of proteasomal and autophagic pathways."