Malocclusion (Crossbite)

Such malposition and contact of the maxillary and mandibular teeth as to interfere with the highest efficiency during the excursive movements of the jaw that are essential for mastication. (Jablonski, Illustrated Dictionary of Dentistry, 1982)

Also Known As:

Networked: 1753 relevant articles (63 outcomes, 275 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Facial Asymmetry (Hemifacial Microsomia)
2.	Overbite
3.	Retrognathism
4.	Obstructive Sleep Apnea
5.	Wounds and Injuries (Trauma)

Experts

1.	Janson, Guilherme: 21 articles (12/2014 - 04/2003)
2.	Franchi, Lorenzo: 17 articles (11/2015 - 07/2004)
3.	Henriques, José Fernando Castanha: 17 articles (12/2014 - 05/2002)
4.	Pancherz, Hans: 12 articles (09/2015 - 10/2003)
5.	Cozza, Paola: 11 articles (11/2015 - 04/2004)
6.	McNamara, James A: 11 articles (09/2015 - 07/2004)
7.	Baccetti, Tiziano: 11 articles (07/2011 - 07/2004)
8.	Paiva, Saul Martins: 9 articles (05/2015 - 07/2008)
9.	Baek, Seung-Hak: 9 articles (11/2014 - 02/2006)
10.	de Freitas, Marcos Roberto: 9 articles (11/2014 - 04/2003)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Malocclusion:

1.	Stainless Steel (Steel, Stainless)IBA 12/01/2010 - "The sample consisted of 24 Korean adults with Class I malocclusion and minimal crowding, treated by first premolar extractions, sliding mechanics (0.022-in MBT brackets [3M Unitek, Monrovia, Calif] with 0.019 × 0.025-in stainless steel wire) and moderate anchorage. " 01/01/1996 - "Chief disadvantages of the reversed stainless steel crown method for crossbite correction are the difficulty in adapting a preformed crown to fit the tooth in crossbite and the metallic appearance of the steel crown form. " 03/01/1983 - "Anterior crossbite correction in the primary dentition using reversed stainless steel crowns." 01/01/2013 - "If multiple teeth are in crossbite, after opening the bite usual step is to ligate forward or advancement arch made of 0.018" or 0.020" stainless steel or NiTi wire main arch that must be kept separated 2 mm from the slot ofupper incisor braces. " 06/01/1999 - "This study investigated time to first failure of stainless steel orthodontic first permanent molar tubes (Ormco Corp) bonded with a light-cured resin adhesive (Transbond) and assessed whether this was related to patient gender, age of the patient at the start of treatment, the presenting malocclusion, or the operator. "
2.	TransbondIBA 06/01/1999 - "This study investigated time to first failure of stainless steel orthodontic first permanent molar tubes (Ormco Corp) bonded with a light-cured resin adhesive (Transbond) and assessed whether this was related to patient gender, age of the patient at the start of treatment, the presenting malocclusion, or the operator. " 08/01/1998 - "The purpose of this study was to investigate the time to first failure of stainless steel orthodontic brackets (Ormco Corp, Glendora, Calif) bonded with a light-cured resin adhesive (Transbond, 3M Unitek, Monrovia, Calif) and assess whether time to failure was related to the patient's age at the start of treatment or sex, the proficiency of the individual placing the brackets, or the presenting malocclusion. "
3.	isopropyl methylphosphonic acidIBA 03/01/2010 - "(1) The constructed artificial neural network in this study was effective, with 80% accuracy, in determining whether extraction or nonextraction treatment was best for malocclusion patients between 11 and 15 years old; (2) when the clinician is predicting whether an orthodontic treatment requires extraction, the indices "anterior teeth uncovered by incompetent lips" and "IMPA (L1-MP)" should be taken into consideration first." 04/01/1982 - "Treatment variations of IMPA in relation to extraction areas, and the class of malocclusion." 04/01/2007 - "Activator and high-pull headgear combination treatment in these growing patients resulted in a correction of the skeletal Class II relationship (ANB -3.4 degrees), a restriction of maxillary growth (SNA -2.0 degrees, OLp-A -2.3 mm), an advancement of the mandibular structures (SNB +2.6 degrees, FH-NPg +2.3 degrees, OLp-B +2.7 mm, OLp-Pg +2.2 mm), an increase in lower face height (ANS-Me +3.9 mm), a correction of the overjet (-5.4 mm), an improvement in overbite (-2.2 mm), uprighting of the maxillary incisors (U1-FH -5.3 degrees, OLp-U1 -2.5 mm), protrusion of the mandibular incisors (IMPA +2.0 degrees, OLp-L1 +2.7 mm), and a correction of the dental Class II malocclusion (OLp-L6 +3.5 mm). " 03/01/2004 - "These entities summarize the clinical features of a patient's condition with a quantifiable, objective list of target disorders that represent the common elements of an orthodontic diagnosis: overjet, overbite, anterior open bite, lateral open bite, crowding, occlusion, lingual posterior crossbite, buccal posterior crossbite, ANB angle, IMPA, and SN-GoGn angle. "
4.	OxygenIBA 01/01/2015 - "Occlusal reconstruction can increase blood flow velocity of middle cerebral artery and cerebral oxygen saturation and improve oxygen supply of the brain in patients with malocclusion." 01/01/2015 - "To investigate the effect of occlusal reconstruction on blood flow velocity and cerebral oxygen saturation in patients with malocclusion. " 01/01/2015 - "[Effect of occlusal reconstruction on cerebral blood flow and cerebral oxygen saturation in patients with malocclusion]." 11/01/2015 - "The results of this study showed that when rapid maxillary expansion is performed in subjects having posterior crossbite, oxygen saturation is improved. "
5.	Guanosine Diphosphate (GDP)IBA 01/01/2001 - "It guided the general dental practitioner (GDP) through the assessment of a patient's malocclusion and helped ensure that all relevant clinical observations were made and details recorded. " 03/01/1990 - "If a GDP is presented with a malocclusion beyond the scope of normal orthodontic treatment, then referral to an oral surgery/orthodontic clinic is indicated. "
6.	1-phenyl-3,3-dimethyltriazene (PDT)IBA 01/01/2013 - "The PDT protocol is effective in early treatment of skeletal Class II malocclusion." 09/01/2011 - "Group test was composed of 10 patients with functional posterior crossbite treated with PDT. "
7.	Myosin Type I (Myosin IA)IBA 10/01/2013 - "In the total population, expressions of HDAC4 (P = 0.03) and KAT6B (P = 0.004) were significantly greater in subjects with sagittal Class III than in Class II malocclusion, whereas HDAC4 tended to correlate negatively with slow myosin type I and positively with fast myosin gene, especially type IIX. These data support other published reports of epigenetic regulation in the determination of skeletal muscle fiber phenotypes and bone growth. "
8.	Myosins (Myosin)IBA 10/01/2013 - "In the total population, expressions of HDAC4 (P = 0.03) and KAT6B (P = 0.004) were significantly greater in subjects with sagittal Class III than in Class II malocclusion, whereas HDAC4 tended to correlate negatively with slow myosin type I and positively with fast myosin gene, especially type IIX. These data support other published reports of epigenetic regulation in the determination of skeletal muscle fiber phenotypes and bone growth. "
9.	AlloysIBA 01/01/2005 - "The clearance of the various AW sizes and alloys changed with malocclusion. "
10.	TitaniumIBA 04/01/2006 - "The aim of this study was to evaluate skeletal stability after double jaw surgery for correction of skeletal Class III malocclusion to assess if there were any differences between resorbable plate and screws and titanium rigid fixation of the maxilla. " 03/01/2015 - "We report two cases having class III malocclusion with maxillary deficiency treated by using titanium miniplates. " 01/01/2015 - "We found significant differences in the incidence of dental malocclusion (p=0.03) and exposure of the titanium plate (p=0.009). " 06/01/2012 - "From a cohort of subjects requiring the extraction of both upper first premolars and pre-adjusted edgewise appliances to correct their malocclusion, a total of 30 were randomly allocated to receive two different forms of anchorage reinforcement: group A--receiving mini-screw implant and group B--receiving a transpalatal arch Group A subjects received titanium mini-screw implants placed at the start of treatment between the maxillary second premolar and maxillary first molar. " 04/01/2006 - "Stability of skeletal Class III malocclusion after combined maxillary and mandibular procedures: titanium versus resorbable plates and screws for maxillary fixation."

Therapies and Procedures

1.	Functional Orthodontic Appliances (Herbst Appliance) 06/01/1999 - "The results of this study revealed that the Herbst appliance is most effective in the treatment of Class II malocclusion in young adults. " 09/01/1997 - "In conclusion, it was found that the Herbst appliance is most effective in the therapy of Class II, Division 2 malocclusions. " 01/01/1985 - "The Herbst appliance is most effective in the treatment of Class II malocclusions, provided it is used as indicated. " 08/01/2011 - "The mandible moved posteriorly by 1.6 mm, and the mandibular incisors moved forward by 0.2 mm. Change in molar relationship was reduced to 2.2 mm. The maxillary molars moved backward by 0.2 mm, and the mandibular molars moved forward by 0.8 mm. Overcorrection of Class II malocclusion with the edgewise crowned Herbst appliance in the early mixed dentition resulted in a significant reduction in overjet and correction of the molar relationship. " 08/01/1992 - "The sample consisted of 32 subjects (16 boys and 16 girls) with a Class II, division 1 malocclusion treated successfully with the Herbst appliance for an average period of 7 months. "
2.	Palatal Expansion Technique 01/01/2015 - "We conducted a comprehensive meta-analysis of 12 studies to examine whether maxillary protraction face mask associated with rapid maxillary expansion (FM/RME) could be an effective treatment for Class III malocclusion and to evaluate the effect of timing on treatment response. " 03/01/2014 - " reported cases show good results, with bodily maxillary expansion and cross-bite correction without any problems or complications. " 05/01/2005 - "To separate subjects with anterior crossbite and mild maxillary deficiency into two groups: those that can be treated successfully with a 2 x 4 appliance and those that should be treated with reverse headgear and maxillary expansion. " 08/01/2012 - "The null hypothesis was that SME and RME are equally effective in producing skeletal maxillary expansion in patients with posterior crossbite. " 03/01/2000 - "Maxillary expansion is a very useful procedure for arch length augmentation, posterior crossbite treatment and removing cross arch interferences. "
3.	Activator Appliances (Function Activator) 03/01/2013 - "It was demonstrated that the Jasper Jumper is an efficient alternative to Class II malocclusion treatment, providing improvement in the facial profile, although the changes are more dentoalveolar than skeletal." 11/01/2006 - "Both the Twin-block and bionator appliances were effective in correcting molar relationships and reducing overjets in Class II Division 1 malocclusion subjects. " 06/01/2004 - "The activator appliance was effective in treating growing patients with mandibular deficiency: activator therapy corrected Class II malocclusions by a combination of skeletal and dental changes and improved the soft tissue facial profile." 09/01/2015 - "This study suggests that bionator treatment of Class II malocclusion produces favorable results over the long term with a combination of skeletal and dentoalveolar shape changes." 12/01/2014 - "The aim of this study was to evaluate the effects of Class II malocclusion treatment with the Jasper Jumper and the Bionator, associated with fixed appliances. "
4.	Orthodontics 03/01/2010 - "The PAR index is clinically useful to evaluate malocclusion, and the perception of treatment needs was significantly greater when the maxillary protrusion cast had a PAR index of more than 20 and overjet above 5.0 mm. Perceived needs for orthodontic treatment for maxillary protrusion changed with increasing experience and skills in dentistry and orthodontics." 09/01/2007 - "When combined with orthodontics, selective periodontal decortication has been shown to be clinically effective in eliminating severe malocclusions three to four times more rapidly than conventional orthodontic treatment. " 01/01/1997 - "Overall, orthodontics was a readily accepted, cost-effective aspect of treatment that substantially improved the esthetics and function of patients with moderate to severe CPE malocclusion." 04/01/2015 - "Among important areas for attention identified were need for multiscale and multispecies modeling and experimentation for interspecies translation of results; large-scale collaborative efforts within the profession to address the need for adequate sample sizes for future genetic studies of complex traits such as malocclusion; a consortium approach to improve new technologies such as intra-oral scanning and 3D imaging by establishing standards; and harnessing the growing body of knowledge about bone biology for application in orthodontics. " 04/01/2014 - "The purpose of this study was to compare stability after mandibular setback surgery in patients with skeletal Class III malocclusion with and without presurgical orthodontics. "
5.	Osteotomy 11/01/2013 - "Maxillary osteotomies and genioplasty may be effective for the correction of malocclusion and for aesthetics. " 07/01/2003 - "This report demonstrates that osteotomy and realignment of the mandible are effective for the secondary correction of malocclusion after mandibular reconstruction with the free fibula osteoseptocutaneous flap." 06/01/1990 - "We present 2 cases in which we improved facial aesthetics and mandibular function by surgically correcting malocclusion with a Le Fort I osteotomy and maxillary intrusion in patients with manifestations of scleroderma in the face and neck." 07/01/2015 - "The aim of this study was to present the authors' experience with a new surgical technique to correct mild laterognathia and malocclusion by means of an L-inverted midline osteotomy. " 12/01/2014 - "Thirty patients diagnosed with skeletal class III malocclusion and underwent sagittal split ramus osteotomy (SSRO) were enrolled in this study. "