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Maleimides

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 58
- Carboxylic Acids: 83
  - Acyclic Acids
    - Dicarboxylic Acids: 76
      - Maleates: 3
        Maleimides: 4
        Ethylmaleimide: 129
        maleimide: 89
        bisindolylmaleimide I: 85
        ruboxistaurin: 67
        N-(1-anilinonaphthalyl)-4-maleimide: 49
        bisindolylmaleimide: 44
        N-(7-dimethylamino-4-methylcoumarinyl)maleimide: 11
        3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione: 10
        SB 216763: 9
        2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide: 7
        MP4 maleimide-polyethylene glycol-modified hemoglobin: 4
        sulfosuccinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate: 4
        bisindolylmaleimide IX: 3
        bisindolylmaleimide VIII: 3
        N-(4-iodophenethyl)maleimide: 3
        adamantyl maleimide: 2
        bisindolylmaleimide II: 2
        N-(beta-(4-diazophenyl)ethyl)maleimide: 2
        N-phenylmaleimide: 2
        1-(4-(5-maleimidopentyl)aminobenzyl)ethylenediaminetetraacetic acid: 1
        4-(4-N-maleimidomethyl)cyclohexane-1-carboxyl hydrazide: 1
        4-maleimidohippuric acid: 1
        antrodin C: 1
        arcyriacyanin A: 1
        bis(maleimidoethoxy)propane: 1
        bis(N-maleimidomethyl)ether: 1
        CJC 1131: 1
        monomaleimido gold: 1
        N-(2-(4-18F-fluorobenzamido)ethyl)maleimide: 1
        N-(3-pyrene)maleimide: 1
        N-(6-(4-fluorobenzylidene)aminooxyhexyl)maleimide: 1
        N-1-(3,5-dimethyladamantyl)maleimide: 1
        N-methylmaleimide: 1
        naphthalene-1,5-dimaleimide: 1
        Ro 31-7549: 1
        TAN 1813: 1
        1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-n-(4-(p-maleimidophenyl)butyramide)
        1,3,5,7-tetramethyl-8-phenyl-(2-maleimide)-difluoroboradiaza-s-indacene
        1,6-bismaleimidohexane
        1-(3-dimethylaminopropyl)-1H-pyrrole-2,5-dione
        1-(4-Cl-benzyl)-3-Cl-4-(CF3-phenylamino)-1H-pyrrol-2.5-dione
        1-maleimidopyrene-3,6,8-trisulfonate
        1H-3-(4-sulfamoylphenyl)-4-phenyl-pyrrole-2,5-dione
        2-(1-(3-aminopropyl)indol-3-yl)-3-(indol-3-yl)-N-methylmaleimide
        2-(1H-indol-3-yl)-3-pentylamino-maleimide
        2-(3-maleimidopropanamido)-9-(((succinimido)oxycarbonyl)oxymethyl)-7-sulfofluorene
        2-(4-N-maleimidophenyl)-6-methoxybenzofuran
        2-(4-N-maleimidophenyl)-6-methylbenzothiazole
        2-ethyl-3-methylmaleimide
        3-(1-methyl-1H-indol-3-yl)-1-phenyl-4-(1-(3-(piperidin-1-yl)propyl)-1H-pyrazolo(3,4-b)pyridin-3-yl)-1H-pyrrole-2,5-dione
        3-(indole-3-yl)-4-(3,4,5-trimethoxyphenyl)-1H-pyrrole-2,5-dione
        3-(N-maleimidopropionyl)biocytin
        3-bromo-1-methyl-4-(2-methylindolyl)maleimide
        3-methyl-2-vinylmaleimide
        4,4'-bismaleimidodiphenylmethane
        4-(2,3-dimethylmaleimido)hippuric acid
        4-(4-N-maleimidophenyl)butyric acid hydrazide
        4-bromo-3-(1'H-indol-3'-yl)maleimide
        4-fluorobenzaldehyde-O-(2-(2-(2-(pyrrol-2,5-dione-1-yl)ethoxy)ethoxy)ethyl)oxime
        4-maleimide-2,2,6,6-tetramethyl-4-piperidine-N-oxide
        4-maleimidophenyl isocyanate
        4-methyl-3-(1'H-indol-3'-yl)maleimide
        4-nitrobenzylmaleimide
        4-phenylazophenylmaleimide
        5-(N-maleimido)-3-oxapentyl-(2-((3-carboxybenzoyl)thio)acetyl)glycyl-glycyl-glycinate
        5-maleimidyl-2-(m-methylphenyl)benzoxazol
        Alexa Fluor 488 C5-maleimide
        antrocinnamomin A
        antrocinnamomin B
        antrocinnamomin C
        antrocinnamomin D
        antrodin B
        aqabamycin A
        aqabamycin B
        aqabamycin C
        aqabamycin D
        aqabamycin E
        aqabamycin F
        aqabamycin G
        AX4697
        benzophenone-4-maleimide
        bimane-C3-maleimide
        bis(maleidophenyl)PEG2000
        bis(maleimido)ethane
        bisarylmaleimide
        bisindolylmaleimide III
        bisindolylmaleimide V
        bodipy FL N-(2-aminoethyl)maleimide
        butadiene-N-(acetoxyphenyl)maleimide
        citraconimide
        compound 371196
        dextran-maleimide
        ergosterimide
        ethyl 4-(3-methyl-2,5-dioxo(3-pyrrolinyl)amino)-2-(trifluoromethyl)pyrimidine-5-carboxylate
        farinomalein
        fluorodeoxyglucose F18-maleimidehexyloxime
        glutathione hexane maleimide
        glutathione maleimide
        GSK 3987
        hematinic acid
- Imides: 16
  - Maleimides: 4
Heterocyclic Compounds: 60
- 1-Ring Heterocyclic Compounds
  - Azoles: 413
    - Pyrroles: 16
      - Maleimides: 4
        Ethylmaleimide: 129
        maleimide: 89
        bisindolylmaleimide I: 85
        ruboxistaurin: 67
        N-(1-anilinonaphthalyl)-4-maleimide: 49
        bisindolylmaleimide: 44
        N-(7-dimethylamino-4-methylcoumarinyl)maleimide: 11
        3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione: 10
        SB 216763: 9
        2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide: 7
        MP4 maleimide-polyethylene glycol-modified hemoglobin: 4
        sulfosuccinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate: 4
        bisindolylmaleimide IX: 3
        bisindolylmaleimide VIII: 3
        N-(4-iodophenethyl)maleimide: 3
        adamantyl maleimide: 2
        bisindolylmaleimide II: 2
        N-(beta-(4-diazophenyl)ethyl)maleimide: 2
        N-phenylmaleimide: 2
        1-(4-(5-maleimidopentyl)aminobenzyl)ethylenediaminetetraacetic acid: 1
        4-(4-N-maleimidomethyl)cyclohexane-1-carboxyl hydrazide: 1
        4-maleimidohippuric acid: 1
        antrodin C: 1
        arcyriacyanin A: 1
        bis(maleimidoethoxy)propane: 1
        bis(N-maleimidomethyl)ether: 1
        CJC 1131: 1
        monomaleimido gold: 1
        N-(2-(4-18F-fluorobenzamido)ethyl)maleimide: 1
        N-(3-pyrene)maleimide: 1
        N-(6-(4-fluorobenzylidene)aminooxyhexyl)maleimide: 1
        N-1-(3,5-dimethyladamantyl)maleimide: 1
        N-methylmaleimide: 1
        naphthalene-1,5-dimaleimide: 1
        Ro 31-7549: 1
        TAN 1813: 1
        1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-n-(4-(p-maleimidophenyl)butyramide)
        1,3,5,7-tetramethyl-8-phenyl-(2-maleimide)-difluoroboradiaza-s-indacene
        1,6-bismaleimidohexane
        1-(3-dimethylaminopropyl)-1H-pyrrole-2,5-dione
        1-(4-Cl-benzyl)-3-Cl-4-(CF3-phenylamino)-1H-pyrrol-2.5-dione
        1-maleimidopyrene-3,6,8-trisulfonate
        1H-3-(4-sulfamoylphenyl)-4-phenyl-pyrrole-2,5-dione
        2-(1-(3-aminopropyl)indol-3-yl)-3-(indol-3-yl)-N-methylmaleimide
        2-(1H-indol-3-yl)-3-pentylamino-maleimide
        2-(3-maleimidopropanamido)-9-(((succinimido)oxycarbonyl)oxymethyl)-7-sulfofluorene
        2-(4-N-maleimidophenyl)-6-methoxybenzofuran
        2-(4-N-maleimidophenyl)-6-methylbenzothiazole
        2-ethyl-3-methylmaleimide
        3-(1-methyl-1H-indol-3-yl)-1-phenyl-4-(1-(3-(piperidin-1-yl)propyl)-1H-pyrazolo(3,4-b)pyridin-3-yl)-1H-pyrrole-2,5-dione
        3-(indole-3-yl)-4-(3,4,5-trimethoxyphenyl)-1H-pyrrole-2,5-dione
        3-(N-maleimidopropionyl)biocytin
        3-bromo-1-methyl-4-(2-methylindolyl)maleimide
        3-methyl-2-vinylmaleimide
        4,4'-bismaleimidodiphenylmethane
        4-(2,3-dimethylmaleimido)hippuric acid
        4-(4-N-maleimidophenyl)butyric acid hydrazide
        4-bromo-3-(1'H-indol-3'-yl)maleimide
        4-fluorobenzaldehyde-O-(2-(2-(2-(pyrrol-2,5-dione-1-yl)ethoxy)ethoxy)ethyl)oxime
        4-maleimide-2,2,6,6-tetramethyl-4-piperidine-N-oxide
        4-maleimidophenyl isocyanate
        4-methyl-3-(1'H-indol-3'-yl)maleimide
        4-nitrobenzylmaleimide
        4-phenylazophenylmaleimide
        5-(N-maleimido)-3-oxapentyl-(2-((3-carboxybenzoyl)thio)acetyl)glycyl-glycyl-glycinate
        5-maleimidyl-2-(m-methylphenyl)benzoxazol
        Alexa Fluor 488 C5-maleimide
        antrocinnamomin A
        antrocinnamomin B
        antrocinnamomin C
        antrocinnamomin D
        antrodin B
        aqabamycin A
        aqabamycin B
        aqabamycin C
        aqabamycin D
        aqabamycin E
        aqabamycin F
        aqabamycin G
        AX4697
        benzophenone-4-maleimide
        bimane-C3-maleimide
        bis(maleidophenyl)PEG2000
        bis(maleimido)ethane
        bisarylmaleimide
        bisindolylmaleimide III
        bisindolylmaleimide V
        bodipy FL N-(2-aminoethyl)maleimide
        butadiene-N-(acetoxyphenyl)maleimide
        citraconimide
        compound 371196
        dextran-maleimide
        ergosterimide
        ethyl 4-(3-methyl-2,5-dioxo(3-pyrrolinyl)amino)-2-(trifluoromethyl)pyrimidine-5-carboxylate
        farinomalein
        fluorodeoxyglucose F18-maleimidehexyloxime
        glutathione hexane maleimide
        glutathione maleimide
        GSK 3987
        hematinic acid

Experts

1.	Cechinel-Filho, Valdir: 2 articles (01/2015 - 09/2004)
2.	Campos-Buzzi, Fatima: 1 article (01/2015)
3.	Winter, Evelyn: 1 article (01/2015)
4.	Creczynski-Pasa, Tania B: 1 article (01/2015)
5.	Noldin, Vania F: 1 article (01/2015)
6.	Rosolen, Daiane: 1 article (01/2015)
7.	Filippin-Monteiro, Fabiola B: 1 article (01/2015)
8.	Santos-Silva, Maria Cláudia: 1 article (12/2013)
9.	de Moraes, Ana Carolina Rabello: 1 article (12/2013)
10.	Gaspar, Pâmela Cristina: 1 article (12/2013)

Related Diseases

1.	Necrosis 01/01/2015 - "Caspases activities and caspase-independent key genes related to apoptosis were not altered by maleimides, suggesting necrosis as the main cell death process. "
2.	Melanoma (Melanoma, Malignant) 09/01/2004 - "We now show the effects of several related cyclic imides: maleimides (S2, S2.1, S2.2, S3), glutarimides (S4, S5, S6), 4-aminoantipyrine derivatives (L1, F1, AL1, F1.14, F1.2) and sulfonated succinimides (RO1, FA, FE, FD, MC, DMC) on isolated rat liver mitochondria, B16-F10 melanoma cell line, peritoneal macrophages and different bacterial streams. "
3.	Leukemia 12/16/2013 - "Apoptotic events induced by maleimides on human acute leukemia cell lines."
4.	Type 2 Diabetes Mellitus (MODY) 04/01/2003 - "Finally, since increased GSK-3 activity may be linked to pathology in diseases such as Alzheimer's disease and non-insulin-dependent diabetes mellitus, several new GSK-3 inhibitors, such as the aloisines, the paullones and the maleimides, have been developed. "
5.	Alzheimer Disease (Alzheimer's Disease) 04/01/2003 - "Finally, since increased GSK-3 activity may be linked to pathology in diseases such as Alzheimer's disease and non-insulin-dependent diabetes mellitus, several new GSK-3 inhibitors, such as the aloisines, the paullones and the maleimides, have been developed. "

Related Drugs and Biologics

1.	Glycogen Synthase Kinase 3
2.	Caspases
3.	Succinimides
4.	Imides
5.	Ampyrone
6.	chlorfenethol (DMC)