Magnesium

A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.

Networked: 12037 relevant articles (663 outcomes, 2249 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Guerrero-Romero, Fernando: 33 articles (10/2022 - 04/2003)
2.	Song, Yiqing: 26 articles (11/2022 - 01/2004)
3.	Dai, Qi: 25 articles (11/2021 - 09/2007)
4.	Saver, Jeffrey L: 24 articles (01/2022 - 05/2004)
5.	Starkman, Sidney: 21 articles (01/2022 - 05/2004)
6.	Barbagallo, Mario: 20 articles (10/2022 - 02/2003)
7.	Conwit, Robin: 20 articles (01/2022 - 01/2009)
8.	Crowther, Caroline A: 20 articles (01/2022 - 08/2007)
9.	Hamilton, Scott: 20 articles (01/2022 - 01/2009)
10.	Sanossian, Nerses: 20 articles (01/2022 - 01/2009)

Related Diseases

1.	Pain (Aches) 01/01/2020 - "Future, larger-sized trials with good assay sensitivity and better safety assessment and reporting, as well as careful attention to formulations with optimal bioavailability, will serve to better define the role of magnesium in the management of chronic pain." 01/01/2015 - "Intra-articular magnesium resulted in a significant reduction in pain scores in group M compared with group C 1 h, 2 h, 6 h, 8 h and 12 h after the end of surgery, respectively, at rest and with passive motion. " 03/01/2013 - "In the magnesium group, the patients' numerical rating scales revealed a significant reduction in pain intensity. " 07/01/2009 - "Intravenous magnesium significantly improved pain, impairment and quality of life and was well tolerated. " 09/01/2006 - "Intra-articular magnesium administration resulted in a significant reduction in pain scores in Group M compared with Group C 1, 2, 6 and 8 h after the end of surgery [1.7 (0.59), 2.2 (0.69), 2.8 (1.01) and 3.5 (1.10) in Group M; 8.0 (1.25), 5.9 (1.12), 4.4 (0.67) and 4.5 (1.13) in Group C, respectively]. "
2.	Eclampsia 10/01/2010 - "Simulation training is superior to traditional lecture alone for teaching crucial skills for the optimal management of both eclampsia and magnesium toxicity, 2 life-threatening obstetric emergencies." 10/10/2023 - "Despite the number of trials evaluating various magnesium sulphate regimens for eclampsia prophylaxis and treatment, there is still no compelling evidence that one particular regimen is more effective than another. " 09/01/2013 - "The purpose of this study was to determine whether a shortened postpartum course of magnesium sulphate is as effective as the standard Pritchard regimen in controlling fits in eclampsia Between January and June 2011, 98 eclamptic mothers presenting at the labour ward of the University of Maiduguri Teaching Hospital were randomised to receive either the standard Pritchard regimen of magnesium sulphate or a shortened postpartum course in which only two doses of intramuscular magnesium sulphate is given four hours apart. " 04/01/2018 - "Impact statement What is already known on this subject: Efficacy of therapeutic short regime magnesium sulphate in eclampsia has already been reported. " 09/08/2015 - "Magnesium was given in 100% of patients with eclampsia and was effective in controlling convulsions. "
3.	Migraine Disorders (Migraine) 10/01/2021 - "Is high-dose magnesium supplementation helpful in adolescents with migraine?" 11/01/2017 - "After 6 months of magnesium prophylaxis, disability due to migraine significantly decreased, whereas physical and psychosocial well-being improved. " 06/01/1996 - "High-dose oral magnesium appears to be effective in migraine prophylaxis." 06/01/1992 - "On the other hand, there was a significantly greater erythrocyte magnesium deficit in persons suffering from migraine than in controls (in both female and male subjects). " 01/01/2021 - "Clinical trials have demonstrated magnesium supplements to be effective for prophylactic treatment of migraine. "
4.	Asthma (Bronchial Asthma) 11/08/2016 - "While the use of intravenous magnesium sulphate (MgSO4) is an accepted part of the pharmacological management of patients with asthma, there is conflicting information about whether it is beneficial in its nebulised form." 12/01/2009 - "We hypothesized that smooth muscle cell relaxation by magnesium might also be beneficial in chronic severe asthma with persistent airflow limitation. " 09/01/2009 - "Magnesium seems to be beneficial in the treatment of moderate to severe asthma in children. " 09/01/1999 - "At 30 minutes, compared with the placebo group, the magnesium sulphate receiving group had lower clinical asthma scores (4.0+/-0.5 vs. 5.5+/-0.5, p = 0.0002) and a significantly greater percentage of improvement from baseline in PEFR (43.0+/-6.3% vs. 14.6+/-3.7%, p = 0.0002). " 12/01/1996 - "Children treated with intravenous magnesium infusions for moderate to severe asthma had significantly greater improvement in short-term pulmonary function without any significant alteration in blood pressure, suggesting a role for this agent as an adjunct in the treatment of such patients."
5.	Insulin Resistance 12/01/2006 - "Improved insulin sensitivity may be one mechanism by which higher dietary magnesium intake may reduce the risk of developing type 2 DM." 02/06/2017 - "In addition, magnesium supplementation was shown to improve blood pressure control, insulin sensitivity, and endothelial function. " 09/01/2014 - "Magnesium supplements modestly improved fasting glycemia without effect on insulin resistance. " 10/01/2022 - "This study provides evidence of the positive effects of magnesium intervention on insulin sensitivity and oxidative stress in GDM patients." 01/01/2020 - "The aim of this study was to investigate the relationship between serum magnesium levels with insulin resistance in apparently healthy adults. "

Related Drugs and Biologics

1.	Calcium
2.	Potassium
3.	Zinc
4.	Phosphates (Orthophosphate)
5.	Ketamine
6.	Sodium
7.	Phosphorus (Red Phosphorus)
8.	Salts
9.	Analgesics (Analgesic Drugs)
10.	Lidocaine (Xylocaine)

Related Therapies and Procedures

1.	Therapeutics
2.	Coronary Artery Bypass (Coronary Artery Bypass Surgery)
3.	Stents
4.	Intravenous Administration
5.	Drug Therapy (Chemotherapy)