Protein-Lysine 6-Oxidase (Lysyl Oxidase)

09/01/2014 - "In addition, lysyl oxidase (LOX) protein expression was dramatically reduced in the scar of KO hearts. "
10/01/2006 - "This suggests a role for lysyl oxidase in scar formation."
03/01/1999 - "Lysyl oxidase transcripts in peritoneal adhesions and incisional scars."
02/01/1997 - "The lysyl oxidase substrates were observed in parallel, resulting in the stabilization of a scar-like peritumor barrier. "
10/01/2006 - "In late-gestation E19 scarring fetal wounds, lysyl oxidase increased 1.8-fold at 8 hours and 2-fold at 12 hours, which was significantly greater than the changes observed in E17 scarless wounds (p < 0.01 for each). "

06/01/2012 - "The purpose of this study was to investigate the expression of fibulin-5 and lysyl oxidase-like 1 (LOXL1), which play an essential role in the synthesis and assembly of elastic fibers, in the uterosacral ligaments of women with advanced pelvic organ prolapse (POP) compared with controls. "
07/01/2009 - "The purpose of this study was to investigate expression of fibulin-5 and lysyl oxidase-like 1, which play an essential role in synthesis and assembly of elastic fibers in the uterosacral ligament, in samples taken from women with advanced pelvic organ prolapse compared with controls. "
09/01/2014 - "Validation of genetically matched wild-type strain and lysyl oxidase-like 1 knockout mouse model of pelvic organ prolapse."
07/01/2010 - "Suppression of lysyl oxidase gene expression by methylation in pelvic organ prolapse."
07/01/2009 - "Changes in expression of fibulin-5 and lysyl oxidase-like 1 associated with pelvic organ prolapse."

10/01/2006 - "In E17 early-gestation scarless fetal wounds, lysyl oxidase had small increases (<1.5-fold) in expression from 1 to 12 hours. "
10/01/2006 - "Early-gestation fetal scarless wounds have less lysyl oxidase expression."
03/01/1999 - "To evaluate the role of lysyl oxidase in postsurgical adhesion formation and incision wound repair. "
01/01/1982 - "The breaking strength of excised wounds, the isometric shrink tension of skin, and the lysyl oxidase activity of normal and repairing skin were determined. "
10/01/2006 - "In late-gestation E19 scarring fetal wounds, lysyl oxidase increased 1.8-fold at 8 hours and 2-fold at 12 hours, which was significantly greater than the changes observed in E17 scarless wounds (p < 0.01 for each). "

02/01/2013 - "Lysyl oxidase (LOX) is a hypoxia-responsive gene. "
12/01/2012 - "Lysyl oxidase may play a critical role in hypoxia-induced NSCLC cells invasion and migration."
10/01/2012 - "Real-time polymerase chain reaction was performed for hypoxia inducible factor-1α and lysyl oxidase. "
10/06/2011 - "Here, we report the characterization of lysyl oxidase-like protein-2 (LOXL2) as a hypoxia-target expressed in neovessels and accumulated in the endothelial ECM. "
01/01/2011 - "In endothelial cells hypoxia up-regulates lysyl oxidase (LOX), a key enzyme in ECM assembly, relevant to vascular homeostasis. "

01/01/2014 - "A novel function for lysyl oxidase in pluripotent mesenchymal cell proliferation and relevance to inflammation-associated osteopenia."
02/01/2003 - "We suggest that increased crosslinking of mature collagen in the synovial tissue of RA is related to an inflammation-dependent regulation of collagen synthesis in activated synovial fibroblasts, in which lysyl oxidase represents the final enzymatic step for crosslinking."
12/01/2014 - "Lysyl oxidase promotes bleomycin-induced lung fibrosis through modulating inflammation."
02/01/2010 - "Lysyl oxidase resolves inflammation by reducing monocyte chemoattractant protein-1 in abdominal aortic aneurysm."
07/01/1998 - "Inflammation-associated lysyl oxidase protein expression in vivo, and modulation by FGF-2 plus IGF-1."