Lysine (L-Lysine)

04/20/2011 - "Tumor uptake was significantly improved from the 50% ID/g at 24 h observed with diabodies that were pegylated on surface lysine residues. "
05/01/2014 - "We describe here an MHC class II binding peptide from the tumor protein p53, which possesses an acetylated lysine at position 120 (p53110-124/AcK120) that is effective in eliciting CD4(+) T cell responses specific for the acetylated peptide. "
04/01/2015 - "Lysine deacetylases inhibitors (KDACIs) are used in basic research, and many are being investigated in clinical trials for treatment of cancer and other diseases. "
01/01/2015 - "Numerous studies have addressed lysine methylation in the realm of cancer biology. "
01/01/2015 - "The prognostic value of lysine-specific demethylase 1 (LSD1) overexpression in various cancers has been investigated by many studies with inconsistent results. "

11/01/1987 - "This information is important, considering the conflicting results obtained previously by researchers investigating the efficacy of lysine therapy for herpes infections. "
01/01/1987 - "L-Lysine appears to be an effective agent for reduction of occurrence, severity and healing time for recurrent HSV infection."
01/01/2015 - "Finally, and most importantly, several clinical studies with cats have shown that lysine is not effective for the prevention or the treatment of feline herpesvirus 1 infection, and some even reported increased infection frequency and disease severity in cats receiving lysine supplementation. "
07/01/1998 - "These studies permitted the following conclusions: (i) the pK sequence is not essential for gB processing or function in virus infection, (ii) the lysine-rich sequence of gB is responsible for HS binding, and (iii) binding to HS is cooperatively linked to the process of efficient virus entry and lateral spread but is not absolutely required for virus infectivity."
04/01/1994 - "Additional studies showed that neither soluble 30/35 FN nor nonspecific binding of hematopoietic cells to poly-L-lysine-coated plates had any appreciable effect on the infection efficiency of these cells. "

06/01/2014 - "Weight gain (WG), feed intake and feed efficiency were significantly improved with increasing levels of lysine up to 12.9 g kg(-1) diet and thereafter declined (P < 0.05). "
04/01/1991 - "Combining all data gave a significant improvement in both weight gain and FCR with increasing intake of dietary lysine. "
05/01/2004 - "Supplementing the diets with blood meal resulted in higher live weight gains (p<0.001) and improved feed conversion ratios (p<0.001) than supplementing with lysine. "
10/01/2002 - "The efficiency of lysine utilization for overall weight gain (Ln, P < 0.001) and lean accretion (Ln, P < 0.05) improved as the amino acid content of G diets decreased. "
06/01/2004 - "Hen weight gain was improved (P < or = 0.03) by increased dietary lysine (94.2 vs. 135.2 g weight gain/hen). "

08/01/2003 - "Body weight gain as well as feed and ME conversion rate were improved when lysine : ME ratio increased from 0.34 to 0.50, whereby all parameters showed a significant ratio x sex interaction. "
10/01/2003 - "Body weight gain and mortality were not altered as dietary lysine increased; however, feed conversion linearly improved. "
01/01/2000 - "Increasing dietary levels of lysine from 0.62 to 0.78% continuously increased daily body weight gains and improved feed conversion efficiency as well as carcass characteristics. "
10/01/1984 - "When voluntary food intake was used as a covariate in the statistical analysis, increased dietary lysine improved the efficiency of food use for body weight, dry matter, crude protein and ash gains. "
06/01/1983 - "Supplementation of lysine (lys) alone did not improve the gain in body weight in either APC or FAPC, but the addition of lysine improved the feed efficiency of chicks fed the FAPC + Met (.323)."

09/02/2015 - "Moreover, FAP-1 can visualize endogenous FA produced by lysine-specific demethylase 1 in a breast cancer cell model, presaging the potential utility of this chemical approach to probe RCS biology. "
01/01/2015 - "When G9a lysine methyltransferase activity was chemically inhibited in the ER(+) breast cancer cell line MCF7, Sox2 protein levels were decreased. "
01/01/1998 - "VIP analogs, which contain a single lysine amino acid, were synthesized and evaluated using breast cancer cells. "
11/01/1986 - "Evaluation of polyinosinic-polycytidylic and poly-L-lysine in metastatic breast cancer."
01/01/2009 - "Tumors sections from control and SMAR1 treated mice as well as tissues sections from different grades of human breast cancer on poly L-lysine coated slides were used for AFM and SEM studies. "