Lypressin

The porcine antidiuretic hormone (VASOPRESSINS). It is a cyclic nonapeptide that differs from ARG-VASOPRESSIN by one amino acid, containing a LYSINE at residue 8 instead of an ARGININE. Lys-vasopressin is used to treat DIABETES INSIPIDUS or to improve vasomotor tone and BLOOD PRESSURE.

Also Known As:

Networked: 123 relevant articles (2 outcomes, 6 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1.	Dębowski, Dawid: 1 article (03/2022)
2.	Gitlin-Domagalska, Agata: 1 article (03/2022)
3.	Glavaš, Mladena: 1 article (03/2022)
4.	Ptaszyńska, Natalia: 1 article (03/2022)
5.	Rolka, Krzysztof: 1 article (03/2022)
6.	Łęgowska, Anna: 1 article (03/2022)
7.	Cheng, Jilin: 1 article (10/2016)
8.	Jiang, Jingbo: 1 article (10/2016)
9.	Jiang, Liping: 1 article (10/2016)
10.	Lin, Xiaozhu: 1 article (10/2016)

Related Diseases

1.	Amnesia (Dissociative Amnesia) 07/01/1977 - "A single injection of lysine vasopressin (1 microgram/rat SC) administered 1 hr prior to either the acquisition trial or 24 hr retention trial antagonized the amnesia." 05/01/1985 - "Arginine- and lysine-vasopressin also reversed the amnesia at a dose of 100 micrograms/body. " 03/01/1982 - "Amnesia in mice for a passive avoidance response induced by anisomycin injection immediately after training was reversed by 40 micrograms of lysine-vasopressin given one hour before testing. " 03/01/1982 - "Alleviation of anisomycin-induced amnesia by pre-test treatment with lysine- vasopressin." 03/01/1980 - "The effect of lysine vasopressin on diethyldithiocarbamate-induced amnesia for a step-through passive avoidance task was studied in rats. "
2.	Diabetes Insipidus 02/01/1966 - "Diabetes insipidus: a two year study with 8-lysine vasopressin." 01/01/1982 - "Effects of lysine-vasopressin and 1-deamino-8-D-arginine-vasopressin on memory in healthy individuals and diabetes insipidus patients." 10/19/1964 - "THE TREATMENT OF DIABETES INSIPIDUS WITH SYNTHETIC LYSINE-VASOPRESSIN BY INHALATION." 08/10/1963 - "Diabetes insipidus treated with synthetic lysine vasopressin." 07/01/2006 - "In a retrospective study of infants with diabetes insipidus, we examined outcome using subcutaneous (sc) DDAVP, and compared this to infants treated with intranasal lysine vasopressin or DDAVP. "
3.	Body Weight (Weight, Body) 08/01/1981 - "Synthetic lysine-vasopressin (2 IU/kg body weight) terminated pregnancy in the rabbit when administered im on day 20, but not when administered on days 8 through 11 of gestation. " 01/01/1986 - "At menstruation, during recording of intrauterine pressure (18 recording sessions in 11 women), intravenous infusion of lysine vasopressin (LVP, 1 ng/min/kg/body weight) induced an increase of the uterine activity and dysmenorrhoea-like symptoms. " 04/01/1997 - "The women participated on days 1, 2 or 3 of two menstrual cycles, with intrauterine pressure recordings and intravenous bolus injections of 10 pmol/kg body weight of lysine vasopressin given 1 h before and at 1, 2 and 3 h after oral administration of 300 mg of the study drug or of placebo. " 09/01/1988 - "The effect of lysine vasopressin infusion (1 pmol/kg body-weight per min) and of bolus injection of a synthetic oxytocin analogue, 1-deamino-2-D-Tyr(OEt)-4-Thr-8-Orn-oxytocin (10 nmol/kg body-weight), were studied. " 01/01/1987 - "In order to test possible effects of lysine-vasopressin (LVP) on basal and LH-RH-stimulated LH and FSH release, an intravenous bolus of LVP (0.06 IU/kg body weight) was injected alone or 10 min before LH-RH (100 micrograms i.v.) in 33 normal women in the follicular, periovulatory and luteal phase of their menstrual cycle. "
4.	Neoplasms (Cancer) 05/01/1969 - "[In vitro action of lysine-vasopressin on the concentration of ribo- and deoxyribonucleic acids in malignant cerebral tumors. " 10/18/1965 - "[Effects of lysine-vasopressin on the nucleic acid content of cancer tissues in vitro]." 04/01/1994 - "In this study we have investigated the responsiveness of the pituitary-adrenocortical axis to intravenous administration of CRH or lysine vasopressin (LVP) in 16 control dogs, 22 dogs with pituitary-dependent hyperadrenocorticism and five dogs with hyperadrenocorticism due to an adrenocortical tumor, using doses of CRH and LVP that caused equivalent ACTH responses in the control dogs. " 06/05/1999 - "DYNAMIC TESTS: The physiological response of ACTH and also AVP to corticotropin releasing hormone (CRH) in the petrous sinus, the unusual responses of certain corticotropic tumors to dDAVP, or certain forms of ACTH-independent hypercortisolism to lysine vasopressin (LVP) suggest excessive or ectopic expression of RV in corticotropic or adrenal cells: tumorgenesis of these cells could also depend, at least partially, on AVP." 01/01/1980 - "Angiography was performed before and after intraarterial administration of prostaglandin F2 alpha, 8-lysine vasopressin, oxytocin, methylergometrine, noradrenalin, and bradykinin in 62 women with various pelvic tumors. "
5.	Adrenocortical Hyperfunction (Adrenal Gland Hyperfunction) 03/01/1979 - "Eight out of the nine dogs responded to tetracosactide administration, three responded supranormally, It is concluded that in the dog, in contrast to man, the lysine-vasopressin test cannot be used to differentiate between pituitary-dependent hyperadrenocorticism and hyperadrenocorticism due to an adenocortical tumour. " 04/01/1994 - "In this study we have investigated the responsiveness of the pituitary-adrenocortical axis to intravenous administration of CRH or lysine vasopressin (LVP) in 16 control dogs, 22 dogs with pituitary-dependent hyperadrenocorticism and five dogs with hyperadrenocorticism due to an adrenocortical tumor, using doses of CRH and LVP that caused equivalent ACTH responses in the control dogs. " 03/01/1979 - "The response has been studied in nine dogs with hyperadrenocorticism due to adrenocortical tumours to the administration of dexamethasone, insulin, lysine-vasopressin and tetracosactide by measuring the changes in plasma cortisol concentration. "

Related Drugs and Biologics

1.	Arginine Vasopressin (Argipressin)
2.	Puromycin
3.	Peptides (Polypeptides)
4.	Arginine (L-Arginine)
5.	Vasotocin (Argiprestocin)
6.	Posterior Pituitary Hormones
7.	carbobenzoxyprolyl-leucyl-glycinamide
8.	cyclo(leucylglycine)
9.	Adrenocorticotropic Hormone (ACTH)
10.	Hydrocortisone (Cortisol)

Related Therapies and Procedures

1.	Oral Administration
2.	Intravenous Administration
3.	Catheters
4.	Injections
5.	Intravenous Infusions