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Discoid Lupus Erythematosus

A chronic form of cutaneous lupus erythematosus (LUPUS ERYTHEMATOSUS, CUTANEOUS) in which the skin lesions mimic those of the systemic form but in which systemic signs are rare. It is characterized by the presence of discoid skin plaques showing varying degrees of edema, erythema, scaliness, follicular plugging, and skin atrophy. Lesions are surrounded by an elevated erythematous border. The condition typically involves the face and scalp, but widespread dissemination may occur.
Also Known As:
Lupus Erythematosus, Discoid; Lupus Erythematosus, Chronic Cutaneous; Lupus Erythematosus, Cutaneous, Chronic
Networked: 531 relevant articles (29 outcomes, 42 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Systemic Lupus Erythematosus (Libman-Sacks Disease)
2. Prurigo
3. Lichen Planus (Lichen Ruber Planus)
4. Erythema Nodosum
5. Alopecia (Baldness)

Experts

1. Wenzel, Joerg: 3 articles (01/2022 - 01/2002)
2. Werth, V P: 3 articles (01/2022 - 05/2012)
3. Meggitt, S J: 3 articles (12/2018 - 09/2013)
4. Werth, Victoria P: 3 articles (01/2017 - 03/2009)
5. Ordi-Ros, J: 3 articles (08/2016 - 06/2000)
6. Linder, Keith E: 3 articles (05/2015 - 02/2012)
7. Olivry, Thierry: 3 articles (05/2015 - 02/2012)
8. Chong, Benjamin F: 3 articles (06/2014 - 01/2014)
9. Chen, Kaili: 2 articles (10/2022 - 01/2022)
10. Li, Qianwen: 2 articles (10/2022 - 01/2022)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Discoid Lupus Erythematosus:
1. Thalidomide (Thalomid)FDA Link
2. Antimalarials (Antimalarial Agents)IBA
3. Sulfasalazine (Azulfidine)FDA LinkGeneric
4. pimecrolimus (Elidel)FDA Link
5. Antinuclear AntibodiesIBA
6. Clofazimine (Lamprene)FDA Link
7. AcitretinFDA Link
8. GoldIBA
9. AntibodiesIBA
10. Vitamin EFDA LinkGeneric

Therapies and Procedures

1. Therapeutics
2. Lasers (Laser)
3. Dye Lasers
4. Aftercare (After-Treatment)
5. Traction
12/01/2019 - "Certain types of alopecia, such as traction alopecia, discoid lupus erythematosus, and central centrifugal cicatricial alopecia, occur more commonly in African-American individuals than in those of other ethnicities. "
09/01/2014 - "Controls included 30 dermatoscopic images from histologically proven cases of scarring traction alopecia and discoid lupus erythematosus. "
11/01/2013 - "The patterns were compared against the diagnosis obtained by independent expert clinical review, including central centrifugal cicatricial alopecia (CCCA), lichen planopilaris, traction alopecia, frontal fibrosing alopecia, discoid lupus erythematosus, and tufted folliculitis. "
04/01/2014 - "The type and its patient number of alopecia investigated in the study were as below: alopecia areata (n=81), trichotillomania (n=24), tinea captis (n=13), traction alopecia (n=12), lichen planopilaris (n=8), discoid lupus erythematosus (n=7), congenital triangular alopecia (n=2) and pseudopelade of Brocq (n=1). "
09/01/2015 - "We retrospectively, independently and blindly reviewed the trichoscopic images of 454 consecutive patients with alopecia areata (99 cases), trichotillomania (n = 20), acute chemotherapy-induced alopecia (n = 6), acute radiotherapy-induced alopecia (n = 2), tinea capitis (n = 13), lichen planopilaris (n = 33), frontal fibrosing alopecia (n = 60), discoid lupus erythematosus (n = 30), dissecting cellulitis (n = 11), central centrifugal cicatricial alopecia (n = 94) and traction alopecia (n = 86) for the presence of flame hairs. "