Lupus Vulgaris

A form of cutaneous tuberculosis. It is seen predominantly in women and typically involves the NASAL MUCOSA; BUCCAL MUCOSA; and conjunctival mucosa.

Networked: 180 relevant articles (4 outcomes, 4 trials/studies)

Relationship Network

Disease Context: Research Results

Infections: 526564
- Infectious Skin Diseases: 45
  - Bacterial Skin Diseases: 20
    - Cutaneous Tuberculosis: 396
      - Lupus Vulgaris: 180
- Bacterial Infections and Mycoses: 1
  - Bacterial Infections: 24368
    - Bacterial Skin Diseases: 20
      - Cutaneous Tuberculosis: 396
        Lupus Vulgaris: 180
Skin and Connective Tissue Diseases
- Skin Diseases: 13127
  - Infectious Skin Diseases: 45
    - Bacterial Skin Diseases: 20
      - Cutaneous Tuberculosis: 396
        Lupus Vulgaris: 180

Related Diseases

1.	Cutaneous Tuberculosis (Scrofuloderma)
2.	Pulmonary Tuberculosis
3.	Tuberculosis (Tuberculoses)
4.	Granuloma
5.	Sarcoidosis (Schaumann Disease)

Experts

1.	Sardana, Kabir: 2 articles (01/2019 - 01/2008)
2.	Ghorpade, A: 2 articles (04/2006 - 09/2003)
3.	Abualiat, Abdullah Sabra: 1 article (10/2021)
4.	Alfadni, Salaheldin Ahmed: 1 article (10/2021)
5.	Bhat, Yasmeen Jabeen: 1 article (10/2021)
6.	Daing, Amanullah: 1 article (10/2021)
7.	Edris, HalaElbedry: 1 article (10/2021)
8.	Elhag, Omer Elgaili Yousif: 1 article (10/2021)
9.	Nabi, Nahida: 1 article (10/2021)
10.	Nassar, Ahmed Helmy: 1 article (10/2021)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Lupus Vulgaris:

1.	Vitamin D FDA LinkGeneric 08/09/1946 - "Vitamin D as a remedy for lupus vulgaris." 12/01/1948 - "Lupus vulgaris and vitamin D." 03/06/1948 - "Lupus Vulgaris and Vitamin D." 02/15/1952 - "[Current vitamin D therapy of lupus vulgaris]." 11/01/1949 - "[Lupus vulgaris treated with vitamin D shock]."
2.	Ergocalciferols (Ergocalciferol)FDA LinkGeneric 10/01/1957 - "The present status of vitamin D2 in the treatment of lupus vulgaris." 01/01/1953 - "[Cases of lupus vulgaris resistant to vitamin D2 in the Bratislava region]." 10/01/1950 - "[Treatment of lupus vulgaris by vitamin D2 (calciferol)]." 01/01/1950 - "[Lupus vulgaris treated locally with vitamin D2]." 12/01/1949 - "[Skin eruption in facial lupus vulgaris treated with massive doses of vitamin D2]."
3.	Isonicotinic Acids (Isonicotinic Acid)IBA 08/01/1953 - "Lupus vulgaris treated with isonicotinic acid hydrazid (rimifon)." 08/01/1953 - "Lupus vulgaris responsive to isoniazid (rimifon; isonicotinic acid hydrazid)." 07/01/1961 - "[Studies on nucleic acids in lupus vulgaris treated with isonicotinic acid hydrazine (INH)]."
4.	Nucleic AcidsIBA 07/01/1961 - "[Studies on nucleic acids in lupus vulgaris treated with isonicotinic acid hydrazine (INH)]."
5.	hydrazine (hydrazine dihydrochloride)IBA 07/01/1961 - "[Studies on nucleic acids in lupus vulgaris treated with isonicotinic acid hydrazine (INH)]."
6.	Isoniazid (Ftivazide)FDA LinkGeneric 05/01/1969 - "Isoniazid treatment of lupus vulgaris. " 01/01/1966 - "[The treatment of lupus vulgaris with isoniazid]." 05/01/1965 - "[TREATMENT AND FOLLOW-UP OF LUPUS VULGARIS WITH ISONIAZID ONLY]." 10/20/1956 - "Lupus vulgaris treated with isoniazid; present status of the disease." 10/01/1954 - "Isonicotinic Acid Hydrazide in the Treatment of Lupus Vulgaris."
7.	Tuberculin (PPD)IBA 10/01/1997 - "The histopathologic picture was similar to lupus vulgaris and the intradermal tuberculin test showed a strongly positive vesiculobullous reaction after forty-eight hours. " 01/01/1951 - "The response to depot tuberculin studied in patients with lupus vulgaris." 11/01/1936 - "Lupus Vulgaris of the Nose under treatment with Tuberculin." 07/09/1898 - "Short Notes on the Treatment of Lupus Vulgaris with "T.R." Tuberculin." 07/24/1897 - "Six Cases of Lupus Vulgaris Treated by Koch's New Tuberculin: A Preliminary Note."
8.	Streptomycin (Streptomycin Sulfate)FDA Link 04/01/1951 - "Report of a case of lupus vulgaris treated with streptomycin." 01/01/1951 - "[Intracutaneous administration and local infiltration of streptomycin in lupus vulgaris]." 08/01/1949 - "Lupus vulgaris, resistant to calciferol; treated with streptomycin and calciferol." 12/18/1948 - "Combined calciferol and streptomycin in lupus vulgaris." 02/01/1953 - "[Parenteral therapy of lupus vulgaris with streptomycin]."
9.	DNA (Deoxyribonucleic Acid)IBA 01/01/1997 - "Polymerase chain reaction and reverse cross blot hybridization assay for detection of mycobacterial DNA in lupus vulgaris." 02/01/1993 - "Identification of Mycobacterium tuberculosis DNA in a case of lupus vulgaris." 02/01/1993 - "tuberculosis complex DNA was demonstrated in archival skin biopsy specimens from the lesion of lupus vulgaris. " 01/01/1996 - "The PCR has been successfully applied to detect DNA from M tuberculosis in lupus vulgaris and several other forms of skin tuberculosis. " 04/01/2009 - "The tuberculous origin of this ulcerative skin tumor-the lupus vulgaris-as an endogenous reinfection of pulmonary tuberculosis manifestation was confirmed by the detection of Mycobacterium tuberculosis DNA in polymerase chain reaction and the growth of Mycobacterium tuberculosis colonies in the bacterial culture (skin biopsy and bronchial secretion). "
10.	VaccinesIBA 09/01/2021 - "Bacillus Calmette-Guérin vaccine-induced lupus vulgaris in a 3-year-old child." 12/01/2009 - "Bacillus Calmette-Guérin vaccine- induced lupus vulgaris in a child." 09/01/2007 - "This occurrence demonstrates the need for heightened surveillance of Bacillus Calmette-Guérin vaccine-induced lupus vulgaris, given the increasing numbers of overseas adoptions taking place in the United States. " 09/01/2007 - "Bacillus Calmette-Guérin vaccine-induced lupus vulgaris in a child adopted from China." 10/01/2021 - "Bacillus Calmette-Guérin Vaccine-Induced Lupus Vulgaris in a Child with Bronchial Asthma."

Therapies and Procedures

1.	Therapeutics 09/16/2015 - "The lesion improved after antituberculous therapy, confirming the diagnosis of lupus vulgaris." 11/01/2013 - "A therapeutic trial of antituberculous therapy for suspected lupus vulgaris: How long does it take to see clinical improvement?" 01/01/1950 - "[Experimental studies on tubercle bacilli isolated from cutaneous lesions of lupus vulgaris during calciferol therapy]." 03/01/2015 - "We present the case of a 59-year-old man with lupus vulgaris who experienced a paradoxical deterioration of cutaneous lesions after starting antituberculosis therapy. " 03/01/2015 - "Paradoxical reaction to antituberculosis therapy in a patient with lupus vulgaris."
2.	Tattooing 09/01/2015 - "Tattoo inoculation lupus vulgaris in two brothers." 04/01/2006 - "Tattoo inoculation lupus vulgaris in two Indian ladies." 09/01/2003 - "Lupus vulgaris developing after tattooing and remaining exclusively confined to it, in a 40-year-old-lady is reported. " 09/01/2003 - "Lupus vulgaris over a tattoo mark--inoculation tuberculosis." 02/15/2021 - "These include autoimmune diseases (vitiligo), cutaneous disorders (Darier disease), dermal conditions (granuloma faciale), dermal depositions (amyloid, calcinosis cutis, cutaneous focal mucinosis, osteoma cutis, and tattoo), dermatitis, miscellaneous conditions (rhinophyma, sarcoidal reaction, and varicose veins), scars, surgical sites, systemic diseases (sarcoidosis), systemic infections (leischmaniasis, leprosy and lupus vulgaris), and ulcers. "
3.	Phototherapy (Light Therapy) 08/01/2004 - "Niels Ryberg Finsen who won the Nobel Prize in Medicine in 1903 for introducing phototherapy for lupus vulgaris. " 03/01/1948 - "Lupus vulgaris; successful phototherapy." 06/01/2005 - "In 1903, Niels Ryberg Finsen was awarded the Nobel Prize for his invention of light therapy for skin tuberculosis (lupus vulgaris). " 05/01/1997 - "In 1903, Niels Finsen was awarded the Nobel Prize in medicine or physiology for his "Finsen light therapy" for infectious diseases, especially lupus vulgaris. "
4.	Radiotherapy 01/01/1952 - "[Biophysical problems in radiotherapy of lupus vulgaris]." 11/01/1982 - "We encountered those problems severally after radiotherapy of the middle face, for instance for lupus vulgaris or basal cell carcinoma. " 01/01/1979 - "The irradiation had been given for tuberculous lymph-adenitis in 6 of the patients, for lupus vulgaris in one, and thyrotoxicosis in another; the other 3 patients had received radiotherapy for malignant tumours. "
5.	Body Piercing (Piercing, Body) 07/01/2019 - "Herein, we reported the case of a 37-year-old female presenting with lupus vulgaris of the left pinna with a history of ear piercing. " 01/01/2014 - "Lupus vulgaris in a child: a complication of ear piercing."