Lip Neoplasms (Neoplasms, Lip)

02/01/2009 - "During transplant function, lip cancer risk is associated with the duration of immunosuppression, receipt of specific immunosuppressive agents, and UV exposure."
06/01/1996 - "Renal transplant recipients (RTR) represent a large and growing population of individuals on potent immunosuppressant therapy who are at significantly greater risk of developing lip and oral mucosal disease, including lip cancer. "

03/01/2022 - "Analysis was carried out using SAS Enterprise Guidev7.1 and STATAv15.Results Relative incidence of SCC, BCC and lip cancer was significantly elevated with every use of HCTZ. "
10/01/2020 - "For lip cancer (45 cases), ever-use of HCTZ yielded an OR of 2.6 (95% CI: 1.4-5.0) and high HCTZ use (≥25 000 mg) an OR of 4.7 (95% CI: 1.6-13.7). "
01/01/2020 - "Hydrochlorothiazide exposure was associated with an increased risk of SCC, BCC and lip cancer that is not explained following adjustment for smoking and BMI. "
01/01/2020 - "The overall number needed to harm with high-dose cumulative hydrochlorothiazide exposure was: 804 for SCC; 2463 for BCC, and 200 000 for lip cancer but varied by age and sex. "
10/01/2017 - "Hydrochlorothiazide use is strongly associated with an increased risk of lip cancer."

01/01/2022 - "The PICOS outline (Population: lip cancer patients; Intervention: immunostaining with biomarkers in surgical specimens; Comparisons: ANTE versus LC; Outcomes: primary-to identify the immunohistochemical pattern of peritumoral epithelium and secondary-to assess the immunoreactivity of LC epithelium; and Study design: cross-sectional, case-control and cohort studies). "
01/01/2022 - "To identify the immunohistochemical pattern of non-tumoral epithelium adjacent to lip cancer (ANTE) to unveil molecular alterations and potential biomarkers in lip cancer patients. "
01/01/2020 - "The proliferation marker Ki-67 was the most studied biomarker and we observed, through meta-analysis, that it was differently expressed between AC and lip cancer, but not in AC subgroups. "
11/21/2013 - "To estimate the diagnostic accuracy of conventional oral examination (COE), vital rinsing, light-based detection, biomarkers and mouth self examination (MSE), used singly or in combination, for the early detection of PMD or cancer of the lip and oral cavity in apparently healthy adults. "
12/01/2021 - "This literature review is an exhaustive compilation of the research work performed on the role of DNA damage and repair responses in lip carcinoma which will pave a path for researchers to identify predictive DNA repair biomarker/s for lip cancer, and its diagnosis, prevention, and treatment."

09/10/2012 - "In this study, we further characterized the risk of lip cancer associated with these and other commonly used antihypertensive drugs. "
09/10/2012 - "Antihypertensive drugs and lip cancer in non-Hispanic whites."
09/10/2012 - "Sun protection for all: but especially for those receiving certain hypertensive medications: comment on "Antihypertensive drugs and lip cancer in non-Hispanic whites"."
10/01/2018 - "The aim of this article is to summarize the current evidence about the association of antihypertensive use with risk of non-melanoma skin cancer, melanoma, lip cancer and cutaneous lymphoma. "
10/01/2017 - "No association with lip cancer was seen with use of other diuretics or nondiuretic antihypertensives. "

09/01/2013 - "This study investigated the immunohistochemical expression of hMLH1 and hMSH2 proteins in lower lip squamous cell carcinoma (SCC) and actinic cheilitis (AC), to contribute to the understanding of the development of lower lip cancer. "
03/01/2002 - "The results show that there is no correlation to the expression of VEGF, EGFR and P16 protein in OSCC and lip cancers. "
03/01/2002 - "Expression of VEGF, EGFR, p16 protein in OSCC and lip cancers was respectively 71.01%, 46.37%, 28.98% and there were no significance between their positive expressions (P > 0.05) as well as in different sites of them (P > 0.05). "
06/01/2017 - "Podoplanin, ezrin, and Rho-A proteins may have joint participation in tumor invasion of lip cancer."
03/01/2002 - "To detect the expression of vascular endothelial growth factor (VEGF), epidermal growth factor receptor (EGFR), p16 protein in lip cancers and oral squamous cell carcinoma (OSCC) as well as their clinicopathological significance. "

05/23/2022 - "Thiazide diuretic use was also associated with a higher risk of lip cancer (5 studies; n = 161,491; pooled adjusted OR, 1.92; 95% CI, 1.52−2.42; p < 0.001; strength of evidence, very low; small harmful effect), whereas other secondary outcomes were inconclusive. "

12/01/2001 - "This non-randomized Phase II study aimed to estimate the complete response (CR) rate to Foscan-mediated photodynamic therapy (Foscan-PDT) in patients with primary cancer of the lip, duration of CR, and the tolerability and safety of Foscan-PDT. "

02/01/1983 - "The risk of cancer of the lip, however, is greater by a factor of almost 2 than the national average, which is consistent with results from other studies."

12/01/2001 - "This non-randomized Phase II study aimed to estimate the complete response (CR) rate to Foscan-mediated photodynamic therapy (Foscan-PDT) in patients with primary cancer of the lip, duration of CR, and the tolerability and safety of Foscan-PDT. "

05/01/1953 - "Radium treatment of cutaneous and lip cancer."
01/01/1971 - "[Interstitial radiotherapy of lower lip neoplasms using radium]."
06/01/1968 - "Combined x-ray and gamma-radium ray therapy for cancer of the lip."

03/01/2010 - "Our findings confirm that brachytherapy is an effective treatment for lip cancer. "
05/22/2020 - "The present study aimed to report the efficacy and toxicity of our high-dose-rate (HDR) brachytherapy for early stage lip cancer (LC) using customized dental spacers. "
04/01/2019 - "The purpose of this study was to report clinical outcomes of patients treated with pulse-dose-rate brachytherapy (PDR-BT) for lip cancer after insufficient surgery. "
07/01/2023 - "Low-dose-rate brachytherapy (LDR-BT) is a well-established treatment for lip cancer. "
07/01/2023 - "Interstitial Brachytherapy for Lip Cancer: Technical Aspects to Individualize Treatment Approach and Optimize Outcomes."

01/11/2023 - "Definitive radiotherapy is an effective treatment for early-stage lip cancer. "
05/01/2016 - "(R) • Early stage lip cancer can be treated equally well by surgery or radiation therapy. "
04/01/2007 - "Lip cancer is frequently treated with surgery although radiation therapy offers comparable results. "
09/01/1998 - "Radiotherapy for cancer of the lip. "
08/01/1993 - "Based on the excellent results of this review, we would continue to recommend radiation therapy as an effective treatment modality for patients with lip cancer because of the ease by which the entire tumour can be encompassed whilst maintaining excellent cosmetic and functional outcome."

11/01/2017 - "To fabricate and evaluate the efficacy of individualized intraoral stents to minimize the potential side effects of radiation on oral tissues in patients with early stages of lip cancer. "
11/01/2017 - "However, studies investigating the efficacy of individualized intraoral stents in patients with lip cancer have not been reported in the literature. "
11/01/2017 - "Intraoral stents in preventing adverse radiotherapeutic effects in lip cancer patients."
11/01/2017 - "The use of individualized intraoral stents was shown to be promising in reducing the adverse effects of radiation therapy in lip cancer patients. "
11/01/2017 - "Six patients with early stage lip cancer were eligible for curative radiotherapy and personalized intraoral stents. "

01/01/2020 - "This therapy may be a treatment option in lower lip cancers with unresectable lesions, or in those patients who are unwilling to undergo resection."
01/01/2017 - "Resection of lip cancer with negative margins remains the mainstay of therapy. "
03/01/2012 - "The accepted method of therapy for lip cancer is surgical excision and reconstruction. "
10/01/1999 - "T1 and T2 lip cancer: a superselective method of facial arterial infusion therapy--preliminary experience."
01/01/1992 - "[Treatment concepts in surgical therapy of lip cancer]."

12/02/2023 - "The Y-shaped anastomosis is an innovative approach aimed at enhancing the efficiency of microvascular free flap surgeries for improved lip cancer reconstruction outcomes. "
10/31/2023 - "Generally, if the size of a lip cancer defect exceeds 30% of the lower lip, a local flap or free flap is recommended. "