Linseed Oil (Flaxseed Oil)

The fixed oil obtained from the dried ripe seed of linseed, Linum usitatissimum (L. Linaceae). It is used as an emollient in liniments, pastes, and medicinal soaps, and in veterinary medicine as a laxative. It is also called flaxseed oil. (Dorland, 28th ed)

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Networked: 284 relevant articles (32 outcomes, 68 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Asemi, Zatollah: 8 articles (01/2022 - 09/2017)
2.	Taghizadeh, Mohsen: 8 articles (01/2022 - 05/2014)
3.	Deng, Qianchun: 7 articles (10/2018 - 07/2012)
4.	Thompson, Lilian U: 7 articles (01/2018 - 03/2006)
5.	Memarzadeh, Mohammad Reza: 5 articles (01/2022 - 09/2017)
6.	Chen, Jianmin: 5 articles (01/2015 - 03/2006)
7.	Wang, Hao: 4 articles (01/2022 - 02/2017)
8.	Zhang, Xiaoxia: 4 articles (01/2022 - 02/2017)
9.	Babajafari, Siavash: 4 articles (01/2020 - 01/2018)
10.	Liu, Liegang: 4 articles (10/2018 - 07/2012)

Related Diseases

1.	Inflammation (Inflammations) 01/01/2019 - "The present study evaluates the effect of flaxseed oil (FXO) supplementation on adipose tissue macrophages (ATM's), E and D series resolvin (Rv) levels and adipose tissue inflammation. " 01/01/2023 - "Short-term flaxseed oil, rich in omega 3, protects mice against metabolic damage caused by high-fat diet, but not inflammation." 01/01/2022 - "It showed that flaxseed oil supplementation cannot improve body composition and inflammation." 01/01/2019 - "Alteration of adipose tissue immune cell milieu towards the suppression of inflammation in high fat diet fed mice by flaxseed oil supplementation." 01/01/2018 - "Flaxseed oil rich in omega-3 protects aorta against inflammation and endoplasmic reticulum stress partially mediated by GPR120 receptor in obese, diabetic and dyslipidemic mice models."
2.	Atherosclerosis 11/01/2009 - "In conclusion, flaxseed, FLC, and SDG, but not flaxseed oil, suppress atherosclerosis, and FLC and SDG slow progression of atherosclerosis but have no effect on regression. " 01/01/1969 - "Effect of linseed oil on experimental atherosclerosis." 11/01/2022 - "Previous studies reported that flaxseed oil (FO) can alleviate age-related diseases, including improving alcoholic liver disease, atherosclerosis and diabetes. " 06/30/2015 - "Flaxseed oil is characterized by high content of essential polyunsaturated fatty acids (PUFA) promoted as a human dietary supplement protecting against atherosclerosis. " 04/04/2014 - "A combination of flaxseed oil and astaxanthin alleviates atherosclerosis risk factors in high fat diet fed rats."
3.	Keratoconjunctivitis Sicca 01/03/2013 - "The objective of this study was to evaluate the effectiveness of various linseed oil (LO) preparations (oral, topical, oral and topical combined) in treating experimentally induced keratoconjunctivitis sicca (KCS) in rabbits. " 01/03/2013 - "Use of linseed oil to treat experimentally induced keratoconjunctivitis sicca in rabbits." 01/01/2017 - "The objective of this study was to compare the efficacy of two sources of omega 3 and 6, fish oil (FO) and linseed oil (LO), orally administered, alone or in combination, for treating experimentally induced keratoconjunctivitis sicca (KCS) in rabbits. " 07/01/2007 - "Therapy with oral flaxseed oil capsules 1 or 2 g/day reduces ocular surface inflammation and ameliorates the symptoms of keratoconjunctivitis sicca in Sjögren's syndrome patients. " 07/01/2007 - "To evaluate if oral flaxseed oil (Linum usitatissimum), which reduces the inflammation in rheumatoid arthritis, may help keratoconjunctivitis sicca's treatment in Sjögren's syndrome patients. "
4.	Insulin Resistance 10/17/2018 - "Flaxseed Oil Attenuates Hepatic Steatosis and Insulin Resistance in Mice by Rescuing the Adaption to ER Stress." 01/01/2019 - "18 weeks) till they developed insulin resistance and 4, 8 or 16 mg/kg group (HFD group later orally supplemented with 4, 8 or 16 mg/kg body weight flaxseed oil) for 4 weeks.The" 01/01/2016 - "Flaxseed oil during lactation leads to gender-specific effects with more adiposity and dyslipidemia in male and insulin resistance in female. " 01/01/2015 - "Partial Reversal of Obesity-Induced Insulin Resistance Owing to Anti-Inflammatory Immunomodulatory Potential of Flaxseed Oil." 04/01/2018 - "After the 12-week intervention, compared to the placebo, flaxseed oil omega-3 supplementation significantly decreased insulin values (-2.6±7.7 vs.+1.3±3.9 µIU/mL, P=0.01), homeostasis model of assessment-estimated insulin resistance (-0.7±1.7 vs.+0.3±0.9, P=0.01), mF-G scores (-1.2±1.7 vs. -0.1±0.4, P=0.001), and increased quantitative insulin sensitivity check index (+0.01±0.02 vs. -0.01±0.02, P=0.01). "
5.	Obesity 10/09/2021 - "High-intensity interval training (HIIT) and linseed oil (LO) supplementation are effective strategies to reduce obesity-induced oxidative stress. " 10/09/2021 - "Beneficial Effects of High Intensity Interval Training and/or Linseed Oil Supplementation to Limit Obesity-Induced Oxidative Stress in High Fat Diet-Fed Rats." 08/01/2012 - "The results suggest that, due to its ability to improve adipocyte function, ALA-rich flaxseed oil confers health benefits in obesity." 01/01/2015 - "Partial Reversal of Obesity-Induced Insulin Resistance Owing to Anti-Inflammatory Immunomodulatory Potential of Flaxseed Oil." 11/08/2023 - "Dietary flaxseed oil, which is rich in α-linolenic acid, did not induce obesity. "

Related Drugs and Biologics

1.	Fish Oils
2.	Lipids
3.	Olive Oil
4.	Apolipoproteins E (ApoE)
5.	alpha-Linolenic Acid (Linolenic Acid)
6.	Corn Oil (Oil, Corn)
7.	Cholesterol
8.	Omega-3 Fatty Acids (Omega 3 Fatty Acids)
9.	Lignans
10.	lard

Related Therapies and Procedures

1.	Therapeutics
2.	Renal Dialysis (Hemodialysis)
3.	Surgical Instruments (Clip)
4.	Diet Therapy (Therapy, Diet)
5.	Oral Administration