Linseed Oil (Flaxseed Oil)

The fixed oil obtained from the dried ripe seed of linseed, Linum usitatissimum (L. Linaceae). It is used as an emollient in liniments, pastes, and medicinal soaps, and in veterinary medicine as a laxative. It is also called flaxseed oil. (Dorland, 28th ed)

Also Known As:

Networked: 145 relevant articles (14 outcomes, 27 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Thompson, Lilian U: 6 articles (01/2015 - 03/2006)
2.	Chen, Jianmin: 5 articles (01/2015 - 03/2006)
3.	Deng, Qianchun: 4 articles (01/2015 - 01/2012)
4.	Prasad, Kailash: 3 articles (01/2015 - 09/2003)
5.	Yang, Wei: 3 articles (01/2014 - 01/2012)
6.	Xu, Jiqu: 3 articles (01/2014 - 01/2012)
7.	Huang, Fenghong: 3 articles (01/2014 - 01/2012)
8.	Huang, Qingde: 3 articles (01/2014 - 01/2012)
9.	Dwivedi, Chandradhar: 3 articles (01/2011 - 01/2005)
10.	Grummer, R R: 3 articles (10/2009 - 01/2005)

Related Diseases

1.	Inflammation 01/01/2014 - "Dietary flaxseed oil altered the expression of genes involved in inflammation in white blood cells. " 06/15/2011 - "Dietary fish oil and flaxseed oil suppress inflammation and immunity in cats." 02/01/2009 - "Fish oil, but not flaxseed oil, decreases inflammation and prevents pressure overload-induced cardiac dysfunction." 07/01/2007 - "Therapy with oral flaxseed oil capsules 1 or 2 g/day reduces ocular surface inflammation and ameliorates the symptoms of keratoconjunctivitis sicca in Sjögren's syndrome patients. " 01/01/2015 - "Results demonstrated that flaxseed oil containing ALA-PS was synergistically interaction in ameliorating atherosclerosis as well as optimizing overall lipid levels, inhibiting inflammation and reducing oxidative stress. "
2.	Insulin Resistance 01/01/2015 - "Partial Reversal of Obesity-Induced Insulin Resistance Owing to Anti-Inflammatory Immunomodulatory Potential of Flaxseed Oil." 03/01/2009 - "Flaxseed oil prevents trans-10, cis-12-conjugated linoleic acid-induced insulin resistance in mice." 04/01/2006 - "Finally, the "linseed oil" diet decreased the insulin resistance index (-80 %, P<0.001) with a more marked effect in males, in relation to their higher hepatic PPARgamma expression (+90 %, P=0.012). " 11/01/2011 - "Similar results were found in studies conducted with flaxseed oil (predominantly ALA), but the favorable role of flaxseed oil was more obvious in various pathologic conditions (kidney disease, obesity with insulin resistance), resulting in improved bone properties. " 07/01/2009 - "In the omega3-depleted rats given access to the flaxseed oil-enriched diet, both body weight and adipose tissue mass underwent a rapid, pronounced and sustained increase, whilst the plasma glucose concentration and insulin resistance index decreased similarly to those in the control rats. "
3.	Neoplasms (Cancer) 01/01/2011 - "The possible chemopreventive effects of natural Egyptian flaxseed oil on preneoplasia and cancer formation were investigated in a rat medium-term colon carcinogenesis bioassay. " 01/01/2011 - "Cancer chemopreventive potential of the Egyptian flaxseed oil in a rat colon carcinogenesis bioassay--implications for its mechanism of action." 01/01/2005 - "Chemopreventive effects of dietary flaxseed oil on colon tumor development." 12/01/2000 - "At the high dose (0.2 ml) of flaxseed oil, when the omega-6: omega-3 PUFA ratio was closer to 1, there was some delay in the growth of mammary tumors. " 12/01/2000 - "The time course of the mammary tumor incidence pattern was advanced by flaxseed oil compared to the control. "
4.	Atherosclerosis 11/01/2009 - "In conclusion, flaxseed, FLC, and SDG, but not flaxseed oil, suppress atherosclerosis, and FLC and SDG slow progression of atherosclerosis but have no effect on regression. " 11/01/2009 - "Flaxseed, flaxseed with very low ALA, flaxseed oil, flax lignan complex (FLC), and SDG reduce the development of hypercholesterolemic atherosclerosis by 46%, 69%, 0%, 73%, and 34%, respectively, in the rabbit model. " 01/01/1969 - "Effect of linseed oil on experimental atherosclerosis." 01/01/2015 - "Results demonstrated that flaxseed oil containing ALA-PS was synergistically interaction in ameliorating atherosclerosis as well as optimizing overall lipid levels, inhibiting inflammation and reducing oxidative stress. " 01/01/2015 - "This study was designed to evaluate the effects of flaxseed oil containing α-linolenic acid ester of PS (ALA-PS) on atherosclerosis and investigate the underlying mechanisms. "
5.	Breast Neoplasms (Breast Cancer) 08/01/2010 - "Flaxseed oil (FO), which is rich in n-3 fatty acid, is commonly consumed by breast cancer patients because of its potential anti-cancer effects. " 01/01/2015 - "Flaxseed oil (FSO) reduces breast tumorigenesis and HER2 expression in animal models of luminal breast cancer. " 01/01/2015 - "Flaxseed oil enhances the effectiveness of trastuzumab in reducing the growth of HER2-overexpressing human breast tumors (BT-474)." 10/01/2010 - "Flaxseed oil reduces the growth of human breast tumors (MCF-7) at high levels of circulating estrogen." 08/01/2010 - "Flaxseed oil-trastuzumab interaction in breast cancer."

Related Drugs and Biologics

1.	Apolipoproteins E (ApoE)
2.	alpha-Linolenic Acid (Linolenic Acid)
3.	Corn Oil (Oil, Corn)
4.	olive oil
5.	lard
6.	Cholesterol
7.	Mineral Oil (Liquid Paraffin)
8.	Isoproterenol (Isoprenaline)
9.	Omega-3 Fatty Acids (Omega 3 Fatty Acids)
10.	secoisolariciresinol diglucoside

Related Therapies and Procedures

1.	Surgical Instruments (Clip)
2.	Renal Dialysis (Hemodialysis)
3.	Renal Replacement Therapy (Therapies, Renal Replacement)
4.	Transplants (Transplant)
5.	Nephrectomy