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Leukotriene B4

The major metabolite in neutrophil polymorphonuclear leukocytes. It stimulates polymorphonuclear cell function (degranulation, formation of oxygen-centered free radicals, arachidonic acid release, and metabolism). (From Dictionary of Prostaglandins and Related Compounds, 1990)
Also Known As:
Leukotriene B; Leukotriene B-4; Leukotrienes B; 5,12 HETE; 5,12 diHETE; B-4, Leukotriene; Leukotriene B 4; 5,12-HETE; 5,12-diHETE; LTB4; 6,8,10,14-Eicosatetraenoic acid, 5,12-dihydroxy-, (S-(R*,S*-(E,Z,E,Z)))-
Networked: 2114 relevant articles (88 outcomes, 242 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Yokomizo, Takehiko: 23 articles (10/2020 - 08/2002)
2. Haribabu, Bodduluri: 19 articles (01/2020 - 02/2004)
3. Kim, Jae-Hong: 18 articles (12/2021 - 03/2002)
4. Haeggström, Jesper Z: 15 articles (01/2019 - 06/2002)
5. Luster, Andrew D: 13 articles (01/2018 - 10/2003)
6. Shimizu, Takao: 12 articles (01/2018 - 08/2002)
7. Bäck, Magnus: 11 articles (10/2018 - 07/2004)
8. Werz, Oliver: 10 articles (10/2020 - 04/2009)
9. Jala, Venkatakrishna R: 10 articles (01/2018 - 02/2004)
10. Sadik, Christian D: 9 articles (01/2022 - 08/2010)

Related Diseases

1. Inflammation (Inflammations)
2. Colitis
3. Asthma (Bronchial Asthma)
4. Infections
5. Pleurisy (Pleuritis)

Related Drugs and Biologics

1. Leukotriene B4
2. Dinoprostone (PGE2)
3. Leukotriene C4
4. Carrageenan
5. Arachidonate 5-Lipoxygenase (5 Lipoxygenase)
6. Interleukin-8 (Interleukin 8)
7. Peroxidase (Myeloperoxidase)
8. Leukotriene D4
9. Thromboxane A2 (A2, Thromboxane)
10. 6-Ketoprostaglandin F1 alpha (6 Ketoprostaglandin F1 alpha)

Related Therapies and Procedures

1. Therapeutics
2. Oral Administration
3. Renal Dialysis (Hemodialysis)
4. Intraperitoneal Injections
5. Investigational Therapies (Experimental Therapy)